6MD0

Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Oleic Acid

Summary for 6MD0

Entry DOI	10.2210/pdb6md0/pdb
Descriptor	Peroxisome proliferator-activated receptor gamma, OLEIC ACID (3 entities in total)
Functional Keywords	nuclear receptors, tzds, drug design, therapeutic targets, transcription
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	63463.96
Authors	Shang, J.,Kojetin, D.J. (deposition date: 2018-09-03, release date: 2019-01-09, Last modification date: 2023-10-11)
Primary citation	Shang, J.,Brust, R.,Mosure, S.A.,Bass, J.,Munoz-Tello, P.,Lin, H.,Hughes, T.S.,Tang, M.,Ge, Q.,Kamekencka, T.M.,Kojetin, D.J. Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma. Elife, 7:-, 2018 Cited by PubMed: 30575522 DOI: 10.7554/eLife.43320 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation