human RANTES complexed to heparin-derived disaccharide I-S

Summary for 1U4L

Related1hrj 1rtn 1rto 1b3a 1eqt 1u4r 1u4m 1u4p
Related PRD IDPRD_900026
DescriptorSmall inducible cytokine A5, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ACETIC ACID, ... (4 entities in total)
Functional Keywordschemoattractant, cytokine, chemokine, rantes, glycosaminoglycan, protein-heparin disaccharide complex, attractant
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total molecular weight16361.54
Shaw, J.P.,Johnson, Z.,Borlat, F.,Zwahlen, C.,Kungl, A.,Roulin, K.,Harrenga, A.,Wells, T.N.C.,Proudfoot, A.E.I. (deposition date: 2004-07-26, release date: 2004-11-09, Last modification date: 2020-07-29)
Primary citation
Shaw, J.P.,Johnson, Z.,Borlat, F.,Zwahlen, C.,Kungl, A.,Roulin, K.,Harrenga, A.,Wells, T.N.,Proudfoot, A.E.
The X-ray structure of RANTES: heparin-derived disaccharides allows the rational design of chemokine inhibitors.
Structure, 12:2081-2093, 2004
PubMed: 15530372 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2004.08.014
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers80 0.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-12-02