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PDB: 793 件

4ZR1
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Hydroxylase domain of scs7p
分子名称: Ceramide very long chain fatty acid hydroxylase SCS7, TRIDECANE, ZINC ION, ...
著者Zhu, G, Koszelak-Rosenblum, M, Malkowski, M.G, Membrane Protein Structural Biology Consortium (MPSBC)
登録日2015-05-11
公開日2015-07-29
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.6008 Å)
主引用文献The Crystal Structure of an Integral Membrane Fatty Acid alpha-Hydroxylase.
J.Biol.Chem., 290, 2015
4ZR0
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Full length scs7p (only hydroxylase domain visible)
分子名称: Ceramide very long chain fatty acid hydroxylase SCS7, ZINC ION
著者Zhu, G, Koszelak-Rosenblum, M, Malkowski, M.G, Membrane Protein Structural Biology Consortium (MPSBC)
登録日2015-05-11
公開日2015-07-29
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献The Crystal Structure of an Integral Membrane Fatty Acid alpha-Hydroxylase.
J.Biol.Chem., 290, 2015
5XNY
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BU of 5xny by Molmil
Crystal structure of CreD
分子名称: CreD
著者Katsuyama, Y, Sato, Y, Sugai, Y, Higashiyama, Y, Senda, M, Senda, T, Ohnishi, Y.
登録日2017-05-25
公開日2018-03-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Crystal structure of the nitrosuccinate lyase CreD in complex with fumarate provides insights into the catalytic mechanism for nitrous acid elimination
FEBS J., 285, 2018
6F6Y
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BU of 6f6y by Molmil
Crystal structure of galectin-3 CRD in complex with galactopentaose
分子名称: Galectin-3, beta-D-galactopyranose-(1-4)-beta-D-galactopyranose
著者Hakansson, M, Andersen, M.C.F, Clausen, M.H, Logan, D.T.
登録日2017-12-06
公開日2018-12-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Beta-(1-4)-d-galactans: synthesis and binding interactions with galectin-3
To Be Published
7E4D
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BU of 7e4d by Molmil
Crystal structure of PlDBR
分子名称: Double Bond Reductase
著者Sugimoto, K, Senda, M, Senda, T.
登録日2021-02-11
公開日2022-02-02
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Exploration and structure-based engineering of alkenal double bond reductases catalyzing the C alpha C beta double bond reduction of coniferaldehyde.
N Biotechnol, 68, 2022
3N23
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BU of 3n23 by Molmil
Crystal structure of the high affinity complex between ouabain and the E2P form of the sodium-potassium pump
分子名称: MAGNESIUM ION, Na+/K+ ATPase gamma subunit transcript variant a, OUABAIN, ...
著者Yatime, L, Laursen, M, Morth, J.P, Esmann, M, Nissen, P, Fedosova, N.U.
登録日2010-05-17
公開日2011-01-19
最終更新日2014-09-17
実験手法X-RAY DIFFRACTION (4.6 Å)
主引用文献Structural insights into the high affinity binding of cardiotonic steroids to the Na+,K+-ATPase.
J.Struct.Biol., 174, 2011
4H9G
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Probing EF-Tu with a very small brominated fragment library identifies the CCA pocket
分子名称: 5-bromofuran-2-carboxylic acid, AMMONIUM ION, Elongation factor Tu-A, ...
著者Groftehauge, M.K, Therkelsen, M, Taaning, R.H, Skrydstrup, T, Morth, J.P, Nissen, P.
登録日2012-09-24
公開日2013-09-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Identifying ligand-binding hot spots in proteins using brominated fragments.
Acta Crystallogr.,Sect.F, 69, 2013
4HHR
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Crystal Structure of fatty acid alpha-dioxygenase (Arabidopsis thaliana)
分子名称: Alpha-dioxygenase, CALCIUM ION, CHLORIDE ION, ...
著者Goulah, C.C, Zhu, G, Koszelak-Rosenblum, M, Malkowski, M.G.
登録日2012-10-10
公開日2013-02-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献The crystal structure of alpha-Dioxygenase provides insight into diversity in the cyclooxygenase-peroxidase superfamily.
Biochemistry, 52, 2013
3L9J
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BU of 3l9j by Molmil
Selection of a novel highly specific TNFalpha antagonist: Insight from the crystal structure of the antagonist-TNFalpha complex
分子名称: MAGNESIUM ION, TNFalpha, Tumor necrosis factor, ...
著者Byla, P, Andersen, M.H, Thogersen, H.C, Gad, H.H, Hartmann, R.
登録日2010-01-05
公開日2010-02-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Selection of a novel and highly specific TNF{alpha} antagonist: insight from the crystal structure of the antagonist-TNF{alpha} complex
J.Biol.Chem., 285, 2010
6ISV
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BU of 6isv by Molmil
Structure of acetophenone reductase from Geotrichum candidum NBRC 4597 in complex with NAD
分子名称: Acetophenone reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION
著者Koesoema, A.A, Sugiyama, Y, Senda, M, Senda, T, Matsuda, T.
登録日2018-11-19
公開日2019-09-11
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for a highly (S)-enantioselective reductase towards aliphatic ketones with only one carbon difference between side chain.
Appl.Microbiol.Biotechnol., 103, 2019
6K4H
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BU of 6k4h by Molmil
Crystal structure of the PI5P4Kbeta-AMPPNP complex
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
著者Takeuchi, K, Senda, M, Senda, T.
登録日2019-05-23
公開日2020-05-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The GTP responsiveness of PI5P4K beta evolved from a compromised trade-off between activity and specificity.
Structure, 2022
6TRI
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BU of 6tri by Molmil
CI-MOR repressor-antirepressor complex of the temperate bacteriophage TP901-1 from Lactococcus lactis
分子名称: CI, MOR, SULFATE ION
著者Rasmussen, K.K, Blackledge, M, Herrmann, T, Jensen, M.R, Lo Leggio, L.
登録日2019-12-18
公開日2020-08-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.277 Å)
主引用文献Revealing the mechanism of repressor inactivation during switching of a temperate bacteriophage.
Proc.Natl.Acad.Sci.USA, 117, 2020
4IL3
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BU of 4il3 by Molmil
Crystal Structure of S. mikatae Ste24p
分子名称: Ste24p, ZINC ION
著者Pryor Jr, E.E, Horanyi, P.S, Clark, K, Fedoriw, N, Connelly, S.M, Koszelak-Rosenblum, M, Zhu, G, Malkowski, M.G, Dumont, M.E, Wiener, M.C, Membrane Protein Structural Biology Consortium (MPSBC)
登録日2012-12-28
公開日2013-02-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.102 Å)
主引用文献Structure of the integral membrane protein CAAX protease Ste24p.
Science, 339, 2013
6GJE
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BU of 6gje by Molmil
Structure of the Amnionless(20-357)-Cubilin(36-135) complex
分子名称: Cubilin, Protein amnionless
著者Larsen, C, Etzerodt, A, Madsen, M, Skjoedt, K, Moestrup, S.K, Andersen, C.B.F.
登録日2018-05-16
公開日2018-12-19
最終更新日2019-06-12
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural assembly of the megadalton-sized receptor for intestinal vitamin B12uptake and kidney protein reabsorption.
Nat Commun, 9, 2018
6K4G
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BU of 6k4g by Molmil
Crystal structure of the PI5P4Kbeta-GMPPNP complex
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
著者Takeuchi, K, Senda, M, Senda, T.
登録日2019-05-23
公開日2020-05-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The GTP responsiveness of PI5P4K beta evolved from a compromised trade-off between activity and specificity.
Structure, 2022
6ZMV
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BU of 6zmv by Molmil
Structure of muramidase from Trichobolus zukalii
分子名称: GLYCEROL, SULFATE ION, muramidase
著者Moroz, O.V, Blagova, E, Taylor, E, Turkenburg, J.P, Skov, L.K, Gippert, G.P, Schnorr, K.M, Ming, L, Ye, L, Klausen, M, Cohn, M.T, Schmidt, E.G.W, Nymand-Grarup, S, Davies, G.J, Wilson, K.S.
登録日2020-07-04
公開日2021-07-14
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Fungal GH25 muramidases: New family members with applications in animal nutrition and a crystal structure at 0.78 angstrom resolution.
Plos One, 16, 2021
5MM9
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BU of 5mm9 by Molmil
VIM-2_2b. Metallo-beta-Lactamase Inhibitors by Bioisosteric Replacement: Preparation, Activity and Binding
分子名称: (2~{R})-2-diethoxyphosphoryl-5-phenyl-pentane-1-thiol, MAGNESIUM ION, Metallo-beta-lactamase VIM-17, ...
著者Skagseth, S, Akhter, S, Paulsen, M.H, Samuelsen, O, Muhammad, Z, Leiros, H.-K.S, Bayer, A.
登録日2016-12-08
公開日2017-03-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Metallo-beta-lactamase inhibitors by bioisosteric replacement: Preparation, activity and binding.
Eur J Med Chem, 135, 2017
6VJT
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BU of 6vjt by Molmil
Co-crystals of broadly neutralizing antibody with the linear epitope from Hepatitis B surface antigen
分子名称: Heavy Chain Fab Fragment of Monoclonal Ab15, Light Chain Fab Fragment of Monoclonal antibody A15, antigenic region 139-148 of Hepatitis B surface antigen protein
著者Oren, D.A, Nussenzweig, M.C, Wang, Q.
登録日2020-01-17
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.782 Å)
主引用文献A Combination of Human Broadly Neutralizing Antibodies against Hepatitis B Virus HBsAg with Distinct Epitopes Suppresses Escape Mutations.
Cell Host Microbe, 28, 2020
7AJ0
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BU of 7aj0 by Molmil
Crystal structure of PsFucS1 sulfatase from Pseudoalteromonas sp.
分子名称: Arylsulfatase, CALCIUM ION, CHLORIDE ION
著者Roret, T, Mikkelsen, M.D, Czjzek, M, Meyer, A.S.
登録日2020-09-28
公開日2021-09-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A novel thermostable prokaryotic fucoidan active sulfatase PsFucS1 with an unusual quaternary hexameric structure.
Sci Rep, 11, 2021
6VR0
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Agrobacterium Tumefaciens ADP-glucose pyrophosphorylase W106A
分子名称: GLYCEROL, Glucose-1-phosphate adenylyltransferase, SULFATE ION
著者Mascarenhas, R.N, Liu, D, Ballicora, M, Iglesias, A, Asencion, M, Figueroa, C.
登録日2020-02-06
公開日2021-02-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Agrobacterium Tumefaciens ADP-glucose pyrophosphorylase W106A
To Be Published
6WO0
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human Artemis/SNM1C catalytic domain, crystal form 1
分子名称: GLYCEROL, Protein artemis, ZINC ION
著者Karim, F, Liu, S, Laciak, A.R, Volk, L, Rosenblum, M, Curtis, R, Huang, N, Carr, G, Zhu, G.
登録日2020-04-23
公開日2020-07-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural analysis of the catalytic domain of Artemis endonuclease/SNM1C reveals distinct structural features.
J.Biol.Chem., 295, 2020
8PXL
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BU of 8pxl by Molmil
Structure of NADH-DEPENDENT FERREDOXIN REDUCTASE, BPHA4, solved at wavelength 1.37 A
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, FORMIC ACID, Ferredoxin reductase, ...
著者El Omari, K, Duman, R, Mykhaylyk, V, Orr, C, Senda, M, Matsugaki, N, Kawano, Y, Wagner, A.
登録日2023-07-23
公開日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Experimental phasing opportunities for macromolecular crystallography at very long wavelengths.
Commun Chem, 6, 2023
8PXK
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Structure of NADH-DEPENDENT FERREDOXIN REDUCTASE, BPHA4, solved at wavelength 5.76 A
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Ferredoxin reductase
著者El Omari, K, Duman, R, Mykhaylyk, V, Orr, C, Senda, M, Matsugaki, N, Kawano, Y, Wagner, A.
登録日2023-07-23
公開日2023-10-25
実験手法X-RAY DIFFRACTION (3.77 Å)
主引用文献Experimental phasing opportunities for macromolecular crystallography at very long wavelengths.
Commun Chem, 6, 2023
6WNL
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BU of 6wnl by Molmil
human Artemis/SNM1C catalytic domain, crystal form 2
分子名称: Protein artemis, ZINC ION
著者Karim, F, Liu, S, Laciak, A.R, Volk, L, Rosenblum, M, Curtis, R, Huang, N, Carr, G, Zhu, G.
登録日2020-04-22
公開日2020-07-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Structural analysis of the catalytic domain of Artemis endonuclease/SNM1C reveals distinct structural features.
J.Biol.Chem., 295, 2020
3K8G
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Structure of crystal form I of TP0453
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 30kLP
著者Zhu, G, Luthra, A, Desrosiers, D, Koszelak-Rosenblum, M, Mulay, V, Radolf, J.D, Malkowski, M.G.
登録日2009-10-14
公開日2010-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Transition from Closed to Open Conformation of Treponema pallidum Outer Membrane-associated Lipoprotein TP0453 Involves Membrane Sensing and Integration by Two Amphipathic Helices.
J.Biol.Chem., 286, 2011

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