6ISV

Structure of acetophenone reductase from Geotrichum candidum NBRC 4597 in complex with NAD

Summary for 6ISV

Entry DOI	10.2210/pdb6isv/pdb
Descriptor	Acetophenone reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION, ... (4 entities in total)
Functional Keywords	nad binding, oxidoreductase
Biological source	Geotrichum candidum (Oospora lactis)
Total number of polymer chains	2
Total formula weight	82268.10
Authors	Koesoema, A.A.,Sugiyama, Y.,Senda, M.,Senda, T.,Matsuda, T. (deposition date: 2018-11-19, release date: 2019-09-11, Last modification date: 2024-03-27)
Primary citation	Koesoema, A.A.,Sugiyama, Y.,Xu, Z.,Standley, D.M.,Senda, M.,Senda, T.,Matsuda, T. Structural basis for a highly (S)-enantioselective reductase towards aliphatic ketones with only one carbon difference between side chain. Appl.Microbiol.Biotechnol., 103:9543-9553, 2019 Cited by PubMed: 31482280 DOI: 10.1007/s00253-019-10093-w PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation