6ISV

Structure of acetophenone reductase from Geotrichum candidum NBRC 4597 in complex with NAD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Acetophenone reductase	polymer	375	40339.8	2	UniProt (M5A8V4) Pfam (PF08240) Pfam (PF00107) In PDB	Geotrichum candidum (Oospora lactis)
2	A, B	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
3	A, B	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
4		water	water		18.0	48	Chemie (HOH)

Sequence modifications

A, B: 1 - 342 (UniProt: M5A8V4)

PDB	External Database	Details
Met 343	-	expression tag
Ala 344	-	expression tag
Ser 345	-	expression tag
Met 346	-	expression tag
Thr 347	-	expression tag
Gly 348	-	expression tag
Gly 349	-	expression tag
Gln 350	-	expression tag
Gln 351	-	expression tag
Met 352	-	expression tag
Gly 353	-	expression tag
Arg 354	-	expression tag
Asp 355	-	expression tag
Pro 356	-	expression tag
Asn 357	-	expression tag
Ser 358	-	expression tag
Ser 359	-	expression tag
Ser 360	-	expression tag
Val 361	-	expression tag
Asp 362	-	expression tag
Lys 363	-	expression tag
Leu 364	-	expression tag
Ala 365	-	expression tag
Ala 366	-	expression tag
Ala 367	-	expression tag
Leu 368	-	expression tag
Glu 369	-	expression tag
His 370	-	expression tag
His 371	-	expression tag
His 372	-	expression tag
His 373	-	expression tag
His 374	-	expression tag
His 375	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	80679.6
Non-Polymers*	Number of molecules	6
	Total formula weight	1588.5
All*	Total formula weight	82268.1

*Water molecules are not included.