6J7W
| Crystal Structure of Human BCMA in complex with UniAb(TM) VH | Descriptor: | Tumor necrosis factor receptor superfamily member 17, UniAb | Authors: | Clarke, S.C, Ma, B, Trinklein, N.D, Schellenberger, U, Osborn, M, Ouisse, L, Boudreau, A, Davison, L, Harris, K.E, Ugamraj, H, Balasubramani, A, Dang, K, Jorgensen, B, Ogana, H, Pham, D, Pratap, P, Sankaran, P, Anegon, I, van Schooten, W, Bruggemann, M, Buelow, R, Force Aldred, S. | Deposit date: | 2019-01-18 | Release date: | 2019-02-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Multispecific Antibody Development Platform Based on Human Heavy Chain Antibodies Front Immunol, 9, 2018
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5JX7
| Cysteine mutant (C224A) structure of As (III) S-adenosyl methyltransferase | Descriptor: | Arsenic methyltransferase, CALCIUM ION | Authors: | Packianathan, C, Marapakala, K, Ajees, A.A, Kandavelu, P, Sankaran, B, Rosen, B.P. | Deposit date: | 2016-05-12 | Release date: | 2017-05-17 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Cysteine mutant (C224A) structure of As (III) S-adenosyl methyltransferase To be Published
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7AG5
| Structure of the Laspartomycin C double mutant G4D D-allo-Thr9D-Dap in complex with Geranyl phosphate | Descriptor: | (~{E})-13-methyltetradec-2-enoic acid, CALCIUM ION, Geranyl phosphate, ... | Authors: | Zeronian, M.R, Pearce, N.M, Wood, T.M, Martin, N.I, Janssen, B.J.C. | Deposit date: | 2020-09-21 | Release date: | 2022-02-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.04 Å) | Cite: | Mechanistic insights into the C55-P targeting lipopeptide antibiotics revealed by structure-activity studies and high-resolution crystal structures Chem Sci, 13, 2022
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6FFY
| Structure of the mouse SorCS2-NGF complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-nerve growth factor, VPS10 domain-containing receptor SorCS2, ... | Authors: | Leloup, N.O.L, Janssen, B.J.C. | Deposit date: | 2018-01-09 | Release date: | 2018-08-01 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Structural insights into SorCS2-Nerve Growth Factor complex formation. Nat Commun, 9, 2018
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8P6I
| Crystal structure of the 139H2 Fab fragment bound to Muc1 peptide epitope | Descriptor: | 139H2 HC, 139H2 LC, Mucin-1 | Authors: | Beugelink, J.W, Peng, W, Siborova, M, Pronker, M.F, Snijder, J, Janssen, B.J.C. | Deposit date: | 2023-05-26 | Release date: | 2024-04-03 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Reverse-engineering the anti-MUC1 antibody 139H2 by mass spectrometry-based de novo sequencing. Life Sci Alliance, 7, 2024
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4FS8
| The structure of an As(III) S-adenosylmethionine methyltransferase: insights into the mechanism of arsenic biotransformation | Descriptor: | Arsenic methyltransferase, CALCIUM ION | Authors: | Ajees, A.A, Marapakala, K, Packianathan, C, Sankaran, B, Rosen, B.P. | Deposit date: | 2012-06-27 | Release date: | 2012-07-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structure of an As(III) S-Adenosylmethionine Methyltransferase: Insights into the Mechanism of Arsenic Biotransformation. Biochemistry, 51, 2012
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5NMR
| Monomeric mouse Sortilin extracellular domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Leloup, N.O.L, Loessl, P, Meijer, D.H.M, Heck, A.J.R, Thies-Weesie, D.M.E, Janssen, B.J.C. | Deposit date: | 2017-04-07 | Release date: | 2017-12-06 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release. Nat Commun, 8, 2017
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4RSR
| ArsM arsenic(III) S-adenosylmethionine methyltransferase with trivalent phenyl arsencial derivative-Roxarsone | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 4-arsanyl-2-nitrophenol, Arsenic methyltransferase, ... | Authors: | Packianathan, C, Marapakala, K, Ajees, A.A, Kandavelu, P, Rosen, B.P. | Deposit date: | 2014-11-10 | Release date: | 2014-12-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | A disulfide-bond cascade mechanism for arsenic(III) S-adenosylmethionine methyltransferase. Acta Crystallogr.,Sect.D, 71, 2015
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7NP5
| ROR(gamma)t ligand binding domain in complex with allosteric ligand FM216 | Descriptor: | 4-[[3-[2-chloranyl-6-(trifluoromethyl)phenyl]-5-(1~{H}-pyrrol-3-yl)-1,2-oxazol-4-yl]methoxy]-2-fluoranyl-benzoic acid, Nuclear receptor ROR-gamma | Authors: | Oerlemans, G.J.M, Somsen, B.A, de Vries, R.M.J.M, Meijer, F.A, Brunsveld, L. | Deposit date: | 2021-02-26 | Release date: | 2021-06-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structure-Activity Relationship Studies of Trisubstituted Isoxazoles as Selective Allosteric Ligands for the Retinoic-Acid-Receptor-Related Orphan Receptor gamma t. J.Med.Chem., 64, 2021
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7NP6
| ROR(gamma)t ligand binding domain in complex with allosteric ligand FM257 | Descriptor: | 4-[[3-[2-chloranyl-6-(trifluoromethyl)phenyl]-5-(1~{H}-pyrazol-4-yl)-1,2-oxazol-4-yl]methoxy]benzoic acid, Nuclear receptor ROR-gamma | Authors: | Oerlemans, G.J.M, Somsen, B.A, de Vries, R.M.J.M, Meijer, F.A, Brunsveld, L. | Deposit date: | 2021-02-26 | Release date: | 2021-06-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Structure-Activity Relationship Studies of Trisubstituted Isoxazoles as Selective Allosteric Ligands for the Retinoic-Acid-Receptor-Related Orphan Receptor gamma t. J.Med.Chem., 64, 2021
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8RMO
| Crystal structure of anti-FLAG M2 Fab fragment bound to FLAG-tag peptide epitope | Descriptor: | CHLORIDE ION, FLAG-tag, anti-FLAG M2 heavy chain, ... | Authors: | Beugelink, J.W, Janssen, B.J.C, Pronker, M.F. | Deposit date: | 2024-01-08 | Release date: | 2024-04-03 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (1.163 Å) | Cite: | Structural Basis for Recognition of the FLAG-tag by Anti-FLAG M2. J.Mol.Biol., 436, 2024
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5HCW
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7O74
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5AMO
| Structure of a mouse Olfactomedin-1 disulfide-linked dimer of the Olfactomedin domain and part of the coiled coil | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Pronker, M.F, Bos, T.G.A.A, Sharp, T.H, Thies-Weesie, D.M, Janssen, B.J.C. | Deposit date: | 2015-03-11 | Release date: | 2015-04-29 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Olfactomedin-1 Has a V-Shaped Disulfide-Linked Tetrameric Structure. J.Biol.Chem., 290, 2015
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3B8E
| Crystal structure of the sodium-potassium pump | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, MAGNESIUM ION, Na+/K+ ATPase gamma subunit transcript variant a, ... | Authors: | Morth, J.P, Pedersen, P.B, Toustrup-Jensen, M.S, Soerensen, T.L.M, Petersen, J, Andersen, J.P, Vilsen, B, Nissen, P. | Deposit date: | 2007-11-01 | Release date: | 2007-12-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Crystal structure of the sodium-potassium pump. Nature, 450, 2007
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4K1C
| VCX1 Calcium/Proton Exchanger | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, IODIDE ION, ... | Authors: | Waight, A.B, Pedersen, B.P, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP) | Deposit date: | 2013-04-04 | Release date: | 2013-05-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for alternating access of a eukaryotic calcium/proton exchanger. Nature, 499, 2013
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6RPB
| Crystal structure of the T-cell receptor NYE_S1 bound to HLA A2*01-SLLMWITQV | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | Authors: | Coles, C.H, Mulvaney, R, Malla, S, Lloyd, A, Smith, K, Chester, F, Knox, A, Stacey, A.R, Dukes, J, Baston, E, Griffin, S, Vuidepot, A, Jakobsen, B.K, Harper, S. | Deposit date: | 2019-05-14 | Release date: | 2020-01-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide-HLA Complex. J Immunol., 204, 2020
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6RP9
| Crystal structure of the T-cell receptor NYE_S3 bound to HLA A2*01-SLLMWITQV | Descriptor: | Beta-2-microglobulin, Cancer/testis antigen 1, HLA class I histocompatibility antigen, ... | Authors: | Coles, C.H, Mulvaney, R, Malla, S, Lloyd, A, Smith, K, Chester, F, Knox, A, Stacey, A.R, Dukes, J, Baston, E, Griffin, S, Vuidepot, A, Jakobsen, B.K, Harper, S. | Deposit date: | 2019-05-14 | Release date: | 2020-01-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.12 Å) | Cite: | TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide-HLA Complex. J Immunol., 204, 2020
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6RPA
| Crystal structure of the T-cell receptor NYE_S2 bound to HLA A2*01-SLLMWITQV | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | Authors: | Coles, C.H, Mulvaney, R, Malla, S, Lloyd, A, Smith, K, Chester, F, Knox, A, Stacey, A.R, Dukes, J, Baston, E, Griffin, S, Vuidepot, A, Jakobsen, B.K, Harper, S. | Deposit date: | 2019-05-14 | Release date: | 2020-01-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide-HLA Complex. J Immunol., 204, 2020
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5C6X
| Crystal structure of C-As lyase with Co(II) | Descriptor: | COBALT (II) ION, GLYCEROL, Glyoxalase/bleomycin resistance protein/dioxygenase, ... | Authors: | Venkadesh, S, Yoshinaga, M, Sankaran, B, Kandavelu, P, Rosen, B.P. | Deposit date: | 2015-06-23 | Release date: | 2016-07-13 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of C-As lyase with Co(II) To Be Published
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5CB9
| Crystal structure of C-As lyase with mercaptoethonal | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Glyoxalase/bleomycin resistance protein/dioxygenase, ... | Authors: | Venkadesh, S, Yoshinaga, M, Sankaran, B, Kandavelu, P, Rosen, B.P. | Deposit date: | 2015-06-30 | Release date: | 2016-07-13 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of C-As lyase with mercaptoethonal To Be Published
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4FB3
| Polyomavirus T-ag binds symmetrical repeats at the viral origin in an asymmetrical manner | Descriptor: | Large T antigen, ORI DNA oligonucleotide-Crick strand, ORI DNA oligonucleotide-Watson strand | Authors: | Bohm, A, Harrison, C.J, Schaffhausen, B.S, Jiang, T. | Deposit date: | 2012-05-22 | Release date: | 2013-10-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.79 Å) | Cite: | Polyomavirus large T antigen binds symmetrical repeats at the viral origin in an asymmetrical manner. J.Virol., 87, 2013
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4FSD
| ArsM arsenic(III) S-adenosylmethionine methyltransferase with As(III) | Descriptor: | ARSENIC, Arsenic methyltransferase, CALCIUM ION, ... | Authors: | Ajees, A.A, Marapakala, K, Packianathan, C, Sankaran, B, Rosen, B.P. | Deposit date: | 2012-06-27 | Release date: | 2012-07-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure of an As(III) S-Adenosylmethionine Methyltransferase: Insights into the Mechanism of Arsenic Biotransformation. Biochemistry, 51, 2012
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6STK
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6STE
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