7AG5

Structure of the Laspartomycin C double mutant G4D D-allo-Thr9D-Dap in complex with Geranyl phosphate

Summary for 7AG5

Entry DOI	10.2210/pdb7ag5/pdb
Descriptor	Laspartomycin C double mutant G4D D-allo-Thr9D-Dap, CALCIUM ION, Geranyl phosphate, ... (5 entities in total)
Functional Keywords	antibiotic, calcium-dependent antibiotic, bacterial cell wall biosynthesis inhibitor, lipopeptide antibiotic
Biological source	Streptomyces viridochromogenes
Total number of polymer chains	1
Total formula weight	1641.85
Authors	Zeronian, M.R.,Pearce, N.M.,Wood, T.M.,Martin, N.I.,Janssen, B.J.C. (deposition date: 2020-09-21, release date: 2022-02-02, Last modification date: 2024-01-31)
Primary citation	Wood, T.M.,Zeronian, M.R.,Buijs, N.,Bertheussen, K.,Abedian, H.K.,Johnson, A.V.,Pearce, N.M.,Lutz, M.,Kemmink, J.,Seirsma, T.,Hamoen, L.W.,Janssen, B.J.C.,Martin, N.I. Mechanistic insights into the C55-P targeting lipopeptide antibiotics revealed by structure-activity studies and high-resolution crystal structures Chem Sci, 13:2985-2991, 2022 Cited by DOI: 10.1039/D1SC07190D PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.04 Å)

Structure validation