1K7K
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![BU of 1k7k by Molmil](/molmil-images/mine/1k7k) | crystal structure of RdgB- inosine triphosphate pyrophosphatase from E. coli | 分子名称: | Hypothetical protein yggV | 著者 | Sanishvili, R, Joachimiak, A, Edwards, A, Savchenko, A, Skarina, T, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2001-10-19 | 公開日 | 2002-08-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Molecular basis of the antimutagenic activity of the house-cleaning inosine triphosphate pyrophosphatase RdgB from Escherichia coli. J.Mol.Biol., 374, 2007
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1M3S
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![BU of 1m3s by Molmil](/molmil-images/mine/1m3s) | Crystal structure of YckF from Bacillus subtilis | 分子名称: | Hypothetical protein yckf | 著者 | Sanishvili, R, Wu, R, Kim, D.E, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2002-06-28 | 公開日 | 2003-01-21 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure of Bacillus subtilis YckF: structural and functional evolution. J.Struct.Biol., 148, 2004
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1NI9
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![BU of 1ni9 by Molmil](/molmil-images/mine/1ni9) | 2.0 A structure of glycerol metabolism protein from E. coli | 分子名称: | Protein glpX, SULFATE ION | 著者 | Sanishvili, R, Brunzelle, J, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2002-12-23 | 公開日 | 2003-07-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural and Biochemical Characterization of the Type II Fructose-1,6-bisphosphatase GlpX from Escherichia coli. J.Biol.Chem., 284, 2009
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1MKZ
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![BU of 1mkz by Molmil](/molmil-images/mine/1mkz) | Crystal structure of MoaB protein at 1.6 A resolution. | 分子名称: | ACETIC ACID, Molybdenum cofactor biosynthesis protein B, SULFATE ION | 著者 | Sanishvili, R, Skarina, T, Joachimiak, A, Edwards, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2002-08-29 | 公開日 | 2003-04-22 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The crystal structure of Escherichia coli MoaB suggests a probable role in molybdenum cofactor synthesis. J.Biol.Chem., 279, 2004
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1M33
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![BU of 1m33 by Molmil](/molmil-images/mine/1m33) | Crystal Structure of BioH at 1.7 A | 分子名称: | 1,2-ETHANEDIOL, 3-HYDROXY-PROPANOIC ACID, BioH protein | 著者 | Sanishvili, R, Savchenko, A, Skarina, T, Edwards, A, Joachimiak, A, Yakunin, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2002-06-26 | 公開日 | 2003-01-21 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Integrating structure, bioinformatics, and enzymology to discover function: BioH, a new carboxylesterase from Escherichia coli. J.Biol.Chem., 278, 2003
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1NIG
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![BU of 1nig by Molmil](/molmil-images/mine/1nig) | |
1CRC
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![BU of 1crc by Molmil](/molmil-images/mine/1crc) | CYTOCHROME C AT LOW IONIC STRENGTH | 分子名称: | CYTOCHROME C, HEME C | 著者 | Sanishvili, R, Volz, K.W, Westbrook, E.M, Margoliash, E. | 登録日 | 1995-03-22 | 公開日 | 1996-03-08 | 最終更新日 | 2021-03-10 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | The low ionic strength crystal structure of horse cytochrome c at 2.1 A resolution and comparison with its high ionic strength counterpart. Structure, 3, 1995
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1YB2
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![BU of 1yb2 by Molmil](/molmil-images/mine/1yb2) | Structure of a putative methyltransferase from Thermoplasma acidophilum. | 分子名称: | hypothetical protein Ta0852 | 著者 | Cuff, M.E, Xu, X, Edwards, A, Savchenko, A, Sanishvili, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2004-12-18 | 公開日 | 2005-02-01 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Structure of a putative methyltransferase from Thermoplasma acidophilum. To be Published
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5EDV
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![BU of 5edv by Molmil](/molmil-images/mine/5edv) | Structure of the HOIP-RBR/UbcH5B~ubiquitin transfer complex | 分子名称: | E3 ubiquitin-protein ligase RNF31, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D2, ... | 著者 | Lechtenberg, B.C, Mace, P.D, Sanishvili, R, Riedl, S.J. | 登録日 | 2015-10-22 | 公開日 | 2016-01-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.48 Å) | 主引用文献 | Structure of a HOIP/E2~ubiquitin complex reveals RBR E3 ligase mechanism and regulation. Nature, 529, 2016
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4LMG
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![BU of 4lmg by Molmil](/molmil-images/mine/4lmg) | Crystal structure of AFT2 in complex with DNA | 分子名称: | 5'-D(*AP*AP*GP*TP*GP*CP*AP*CP*CP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*TP*GP*GP*GP*TP*GP*CP*AP*CP*T)-3', Iron-regulated transcriptional activator AFT2, ... | 著者 | Poor, C.B, Sanishvili, R, Schuermann, J.P, He, C. | 登録日 | 2013-07-10 | 公開日 | 2014-03-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Molecular mechanism and structure of the Saccharomyces cerevisiae iron regulator Aft2. Proc.Natl.Acad.Sci.USA, 111, 2014
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4Y0I
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![BU of 4y0i by Molmil](/molmil-images/mine/4y0i) | GABA-aminotransferase inactivated by conformationally-restricted inactivator | 分子名称: | 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC ACID, 4-aminobutyrate aminotransferase, mitochondrial, ... | 著者 | Wu, R, Sanishvili, R, Lee, H.V, Dustin, D.H, Emma, D, Neil, K, Silverman, R.B, Liu, D. | 登録日 | 2015-02-06 | 公開日 | 2016-02-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.662 Å) | 主引用文献 | GABA-aminotransferase inactivated by conformationally-restricted inactivator To Be Published
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4ZSW
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![BU of 4zsw by Molmil](/molmil-images/mine/4zsw) | Pig Brain GABA-AT inactivated by (E)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic acid | 分子名称: | (1S)-4-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]cyclopent-3-ene-1,3-dicarboxylic acid, 4-aminobutyrate aminotransferase, mitochondrial, ... | 著者 | Wu, R, Lee, H, Le, H.V, Doud, E, Sanishvili, R, Compton, P, Kelleher, N.L, Silverman, R.B, Liu, D. | 登録日 | 2015-05-14 | 公開日 | 2015-07-08 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid. Acs Chem.Biol., 10, 2015
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4ZSY
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![BU of 4zsy by Molmil](/molmil-images/mine/4zsy) | Pig Brain GABA-AT inactivated by (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic acid. | 分子名称: | (1S)-4-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]cyclopent-3-ene-1,3-dicarboxylic acid, 4-aminobutyrate aminotransferase, mitochondrial, ... | 著者 | Wu, R, Lee, H, Le, H.V, Doud, E, Sanishvili, R, Compton, P, Kelleher, N.L, Silverman, R.B, Liu, D. | 登録日 | 2015-05-14 | 公開日 | 2015-07-08 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid. Acs Chem.Biol., 10, 2015
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6AUN
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![BU of 6aun by Molmil](/molmil-images/mine/6aun) | calcium-independent phospholipase A2 beta | 分子名称: | PLA2G6, iPLA2beta | 著者 | Malley, K, Koroleva, O, Miller, I, Sanishvili, R, Jenkins, C.M, Gross, R.W, Korolev, S. | 登録日 | 2017-09-01 | 公開日 | 2018-03-07 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.951 Å) | 主引用文献 | The structure of iPLA2beta reveals dimeric active sites and suggests mechanisms of regulation and localization. Nat Commun, 9, 2018
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1SRV
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![BU of 1srv by Molmil](/molmil-images/mine/1srv) | THERMUS THERMOPHILUS GROEL (HSP60 CLASS) FRAGMENT (APICAL DOMAIN) COMPRISING RESIDUES 192-336 | 分子名称: | PROTEIN (GROEL (HSP60 CLASS)) | 著者 | Walsh, M.A, Dementieva, I, Evans, G, Sanishvili, R, Joachimiak, A. | 登録日 | 1999-03-02 | 公開日 | 1999-03-12 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Taking MAD to the extreme: ultrafast protein structure determination. Acta Crystallogr.,Sect.D, 55, 1999
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5T4J
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![BU of 5t4j by Molmil](/molmil-images/mine/5t4j) | PLP and GABA Trigger GabR-Mediated Transcription Regulation in Bacillus subsidies via External Aldimine Formation | 分子名称: | GAMMA-AMINO-BUTANOIC ACID, HTH-type transcriptional regulatory protein GabR, PYRIDOXAL-5'-PHOSPHATE | 著者 | Wu, R, Sanishvili, R, Belitsky, B.R, Juncosa, J.I, Le, H.V, Lehrer, H.J.S, Farley, M, Silverman, R.B, Petsko, G.A, Ringe, D, Liu, D. | 登録日 | 2016-08-29 | 公開日 | 2017-03-29 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.231 Å) | 主引用文献 | PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5T4L
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![BU of 5t4l by Molmil](/molmil-images/mine/5t4l) | PLP and GABA Trigger GabR-Mediated Transcription Regulation in Bacillus subsidies via External Aldimine Formation | 分子名称: | (4R)-4-amino-6-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}hexanoic acid, Aspartate aminotransferase | 著者 | Wu, R, Sanishvili, R, Belitsky, B.R, Juncosa, J.I, Le, H.V, Lehrer, H.J.S, Farley, M, Silverman, R.B, Petsko, G.A, Ringe, D, Liu, D. | 登録日 | 2016-08-29 | 公開日 | 2017-03-29 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5T4K
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![BU of 5t4k by Molmil](/molmil-images/mine/5t4k) | PLP and GABA Trigger GabR-Mediated Transcription Regulation in Bacillus subsidies via External Aldimine Formation | 分子名称: | (4S)-5-fluoro-4-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanoic acid, HTH-type transcriptional regulatory protein GabR | 著者 | Wu, R, Sanishvili, R, Belitsky, B.R, Juncosa, J.I, Le, H.V, Lehrer, H.J.S, Farley, M, Silverman, R.B, Petsko, G.A, Ringe, D, Liu, D. | 登録日 | 2016-08-29 | 公開日 | 2017-03-29 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.245 Å) | 主引用文献 | PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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2O4H
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![BU of 2o4h by Molmil](/molmil-images/mine/2o4h) | Human brain aspartoacylase complex with intermediate analog (N-phosphonomethyl-L-aspartate) | 分子名称: | Aspartoacylase, N-[HYDROXY(METHYL)PHOSPHORYL]-L-ASPARTIC ACID, ZINC ION | 著者 | Le Coq, J, Pavlovsky, A, Sanishvili, R, Viola, R.E. | 登録日 | 2006-12-04 | 公開日 | 2007-11-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Examination of the Mechanism of Human Brain Aspartoacylase through the Binding of an Intermediate Analogue. Biochemistry, 47, 2008
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2O53
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![BU of 2o53 by Molmil](/molmil-images/mine/2o53) | Crystal structure of apo-Aspartoacylase from human brain | 分子名称: | Aspartoacylase, PHOSPHATE ION, ZINC ION | 著者 | Le Coq, J, Pavlovsky, A, Sanishvili, R, Viola, R.E. | 登録日 | 2006-12-05 | 公開日 | 2007-11-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Examination of the Mechanism of Human Brain Aspartoacylase through the Binding of an Intermediate Analogue. Biochemistry, 47, 2008
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1US0
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![BU of 1us0 by Molmil](/molmil-images/mine/1us0) | Human Aldose Reductase in complex with NADP+ and the inhibitor IDD594 at 0.66 Angstrom | 分子名称: | ALDOSE REDUCTASE, CITRIC ACID, IDD594, ... | 著者 | Howard, E.I, Sanishvili, R, Cachau, R.E, Mitschler, A, Chevrier, B, Barth, P, Lamour, V, Van Zandt, M, Sibley, E, Bon, C, Moras, D, Schneider, T.R, Joachimiak, A, Podjarny, A. | 登録日 | 2003-11-16 | 公開日 | 2004-05-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (0.66 Å) | 主引用文献 | Ultrahigh Resolution Drug Design I: Details of Interactions in Human Aldose Reductase-Inhibitor Complex at 0.66 A. Proteins, 55, 2004
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2R4S
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![BU of 2r4s by Molmil](/molmil-images/mine/2r4s) | Crystal structure of the human beta2 adrenoceptor | 分子名称: | Beta-2 adrenergic receptor, antibody for beta2 adrenoceptor, heavy chain, ... | 著者 | Rasmussen, S.G.F, Choi, H.J, Rosenbaum, D.M, Kobilka, T.S, Thian, F.S, Edwards, P.C, Burghammer, M, Ratnala, V.R, Sanishvili, R, Fischetti, R.F, Schertler, G.F, Weis, W.I, Kobilka, B.K. | 登録日 | 2007-08-31 | 公開日 | 2007-11-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Crystal structure of the human beta2 adrenergic G-protein-coupled receptor. Nature, 450, 2007
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2R4R
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![BU of 2r4r by Molmil](/molmil-images/mine/2r4r) | Crystal structure of the human beta2 adrenoceptor | 分子名称: | Beta-2 adrenergic receptor, antibody for beta2 adrenoceptor, heavy chain, ... | 著者 | Rasmussen, S.G.F, Choi, H.J, Rosenbaum, D.M, Kobilka, T.S, Thian, F.S, Edwards, P.C, Burghammer, M, Ratnala, V.R, Sanishvili, R, Fischetti, R.F, Schertler, G.F, Weis, W.I, Kobilka, B.K. | 登録日 | 2007-08-31 | 公開日 | 2007-11-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Crystal structure of the human beta2 adrenergic G-protein-coupled receptor. Nature, 450, 2007
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2OBZ
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1I3W
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![BU of 1i3w by Molmil](/molmil-images/mine/1i3w) | ACTINOMYCIN D BINDING TO CGATCGATCG | 分子名称: | 5'-D(*C*GP*AP*TP*CP*GP*AP*(BRU)P*CP*GP)-3', ACTINOMYCIN D | 著者 | Robinson, H, Gao, Y.-G, Yang, X.-L, Sanishvili, R, Joachimiak, A, Wang, A.H.-J. | 登録日 | 2001-02-17 | 公開日 | 2001-05-21 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystallographic Analysis of a Novel Complex of Actinomycin D Bound to the DNA Decamer Cgatcgatcg. Biochemistry, 40, 2001
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