2R4R

Crystal structure of the human beta2 adrenoceptor

Summary for 2R4R

Related2R4S
DescriptorBeta-2 adrenergic receptor, antibody for beta2 adrenoceptor, light chain, antibody for beta2 adrenoceptor, heavy chain (3 entities in total)
Functional Keywordstransmembrane helix, g-protein coupled receptor, glycoprotein, lipoprotein, palmitate, phosphorylation, receptor, transducer, signaling protein
Biological sourceHomo sapiens (human)
More
Cellular locationCell membrane; Multi-pass membrane protein P07550
Total number of polymer chains3
Total molecular weight88420.37
Authors
Primary citation
Rasmussen, S.G.F.,Choi, H.J.,Rosenbaum, D.M.,Kobilka, T.S.,Thian, F.S.,Edwards, P.C.,Burghammer, M.,Ratnala, V.R.,Sanishvili, R.,Fischetti, R.F.,Schertler, G.F.,Weis, W.I.,Kobilka, B.K.
Crystal structure of the human beta2 adrenergic G-protein-coupled receptor.
Nature, 450:383-387, 2007
PubMed: 17952055 (PDB entries with the same primary citation)
DOI: 10.1038/nature06325
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.4 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.271575.9%11.3%10.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report