1G62
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![BU of 1g62 by Molmil](/molmil-images/mine/1g62) | CRYSTAL STRUCTURE OF S.CEREVISIAE EIF6 | Descriptor: | RIBOSOME ANTI-ASSOCIATION FACTOR EIF6 | Authors: | Groft, C.M, Beckmann, R, Sali, A, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2000-11-02 | Release date: | 2000-11-22 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of ribosome anti-association factor IF6. Nat.Struct.Biol., 7, 2000
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1A5T
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![BU of 1a5t by Molmil](/molmil-images/mine/1a5t) | CRYSTAL STRUCTURE OF THE DELTA PRIME SUBUNIT OF THE CLAMP-LOADER COMPLEX OF ESCHERICHIA COLI DNA POLYMERASE III | Descriptor: | DELTA PRIME, ZINC ION | Authors: | Guenther, B, Onrust, R, Sali, A, O'Donnell, M, Kuriyan, J. | Deposit date: | 1998-02-18 | Release date: | 1998-05-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the delta' subunit of the clamp-loader complex of E. coli DNA polymerase III. Cell(Cambridge,Mass.), 91, 1997
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1I9A
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![BU of 1i9a by Molmil](/molmil-images/mine/1i9a) | STRUCTURAL STUDIES OF CHOLESTEROL BIOSYNTHESIS: MEVALONATE 5-DIPHOSPHATE DECARBOXYLASE AND ISOPENTENYL DIPHOSPHATE ISOMERASE | Descriptor: | ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE, MANGANESE (II) ION | Authors: | Bonanno, J.B, Edo, C, Eswar, N, Pieper, U, Romanowski, M.J, Ilyin, V, Gerchman, S.E, Kycia, H, Studier, F.W, Sali, A, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2001-03-18 | Release date: | 2001-03-28 | Last modified: | 2021-02-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural genomics of enzymes involved in sterol/isoprenoid biosynthesis. Proc.Natl.Acad.Sci.USA, 98, 2001
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1G61
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![BU of 1g61 by Molmil](/molmil-images/mine/1g61) | CRYSTAL STRUCTURE OF M.JANNASCHII EIF6 | Descriptor: | TRANSLATION INITIATION FACTOR 6 | Authors: | Groft, C.M, Beckmann, R, Sali, A, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2000-11-02 | Release date: | 2000-11-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Crystal structures of ribosome anti-association factor IF6. Nat.Struct.Biol., 7, 2000
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4TQG
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![BU of 4tqg by Molmil](/molmil-images/mine/4tqg) | Crystal structure of Megavirus UDP-GlcNAc 4,6-dehydratase, 5-epimerase Mg534 | Descriptor: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative dTDP-d-glucose 4 6-dehydratase | Authors: | Jeudy, S, Piacente, F, De Castro, C, Molinaro, A, Salis, A, Damonte, G, Bernardi, C, Tonetti, M, Claverie, J.M, Abergel, C. | Deposit date: | 2014-06-11 | Release date: | 2014-06-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Giant Virus Megavirus chilensis Encodes the Biosynthetic Pathway for Uncommon Acetamido Sugars. J.Biol.Chem., 289, 2014
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4AEC
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![BU of 4aec by Molmil](/molmil-images/mine/4aec) | Crystal Structure of the Arabidopsis thaliana O-Acetyl-Serine-(Thiol)- Lyase C | Descriptor: | ACETATE ION, CYSTEINE SYNTHASE, MITOCHONDRIAL, ... | Authors: | Feldman-Salit, A, Wirtz, M, Lenherr, E.D, Throm, C, Hothorn, M, Scheffzek, K, Hell, R, Wade, R.C. | Deposit date: | 2012-01-09 | Release date: | 2012-02-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Allosterically Gated Enzyme Dynamics in the Cysteine Synthase Complex Regulate Cysteine Biosynthesis in Arabidopsis Thaliana. Structure, 20, 2012
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6D35
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![BU of 6d35 by Molmil](/molmil-images/mine/6d35) | Crystal structure of Xenopus Smoothened in complex with cholesterol | Descriptor: | CHOLESTEROL, Smoothened,Soluble cytochrome b562,Smoothened | Authors: | Huang, P, Zheng, S, Kim, Y, Kruse, A.C, Salic, A. | Deposit date: | 2018-04-14 | Release date: | 2018-05-23 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Structural Basis of Smoothened Activation in Hedgehog Signaling. Cell, 174, 2018
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6Y8O
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![BU of 6y8o by Molmil](/molmil-images/mine/6y8o) | Mycobacterium smegmatis GyrB 22kDa ATPase sub-domain in complex with novobiocin | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, DNA gyrase subunit B, ... | Authors: | Henderson, S.R, Stevenson, C.E.M, Malone, B, Zholnerovych, Y, Mitchenall, L.A, Pichowicz, M, McGarry, D.H, Cooper, I.R, Charrier, C, Salisbury, A, Lawson, D.M, Maxwell, A. | Deposit date: | 2020-03-05 | Release date: | 2020-08-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural and mechanistic analysis of ATPase inhibitors targeting mycobacterial DNA gyrase. J.Antimicrob.Chemother., 75, 2020
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6Y8N
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![BU of 6y8n by Molmil](/molmil-images/mine/6y8n) | Mycobacterium thermoresistibile GyrB21 in complex with Redx03863 | Descriptor: | 1,2-ETHANEDIOL, 4-[(1~{S},5~{R})-6-azanyl-3-azabicyclo[3.1.0]hexan-3-yl]-6-fluoranyl-~{N}-methyl-2-(2-methylpyrimidin-5-yl)oxy-9~{H}-pyrimido[4,5-b]indol-8-amine, DNA gyrase subunit B, ... | Authors: | Henderson, S.R, Stevenson, C.E.M, Malone, B, Zholnerovych, Y, Mitchenall, L.A, Pichowicz, M, McGarry, D.H, Cooper, I.R, Charrier, C, Salisbury, A, Lawson, D.M, Maxwell, A. | Deposit date: | 2020-03-05 | Release date: | 2020-08-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural and mechanistic analysis of ATPase inhibitors targeting mycobacterial DNA gyrase. J.Antimicrob.Chemother., 75, 2020
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6Y8L
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![BU of 6y8l by Molmil](/molmil-images/mine/6y8l) | Mycobacterium thermoresistibile GyrB21 in complex with novobiocin | Descriptor: | 1,2-ETHANEDIOL, DNA gyrase subunit B, NOVOBIOCIN, ... | Authors: | Henderson, S.R, Stevenson, C.E.M, Malone, B, Zholnerovych, Y, Mitchenall, L.A, Pichowicz, M, McGarry, D.H, Cooper, I.R, Charrier, C, Salisbury, A, Lawson, D.M, Maxwell, A. | Deposit date: | 2020-03-05 | Release date: | 2020-08-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural and mechanistic analysis of ATPase inhibitors targeting mycobacterial DNA gyrase. J.Antimicrob.Chemother., 75, 2020
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7RHR
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![BU of 7rhr by Molmil](/molmil-images/mine/7rhr) | Cryo-EM structure of Xenopus Patched-1 in nanodisc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | Authors: | Huang, P, Lian, T, Jiang, J, Salic, A. | Deposit date: | 2021-07-18 | Release date: | 2022-03-02 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis for catalyzed assembly of the Sonic hedgehog-Patched1 signaling complex. Dev.Cell, 57, 2022
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7RHQ
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![BU of 7rhq by Molmil](/molmil-images/mine/7rhq) | Cryo-EM structure of Xenopus Patched-1 in complex with GAS1 and Sonic Hedgehog | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Huang, P, Lian, T, Wierbowski, B, Garcia-Linares, S, Jiang, J, Salic, A. | Deposit date: | 2021-07-18 | Release date: | 2022-03-02 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.53 Å) | Cite: | Structural basis for catalyzed assembly of the Sonic hedgehog-Patched1 signaling complex. Dev.Cell, 57, 2022
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6D32
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![BU of 6d32 by Molmil](/molmil-images/mine/6d32) | Crystal structure of Xenopus Smoothened in complex with cyclopamine | Descriptor: | Cyclopamine, Smoothened,Soluble cytochrome b562,Smoothened | Authors: | Huang, P, Zheng, S, Kim, Y, Kruse, A.C, Salic, A. | Deposit date: | 2018-04-14 | Release date: | 2018-05-23 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.751 Å) | Cite: | Structural Basis of Smoothened Activation in Hedgehog Signaling. Cell, 174, 2018
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5KZV
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![BU of 5kzv by Molmil](/molmil-images/mine/5kzv) | Crystal structure of the xenopus Smoothened cysteine-rich domain (CRD) in complex with 20(S)-hydroxycholesterol | Descriptor: | (3alpha,8alpha)-cholest-5-ene-3,20-diol, Smoothened | Authors: | Huang, P, Kim, Y, Salic, A. | Deposit date: | 2016-07-25 | Release date: | 2016-08-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.616 Å) | Cite: | Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling. Cell, 166, 2016
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5KZY
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![BU of 5kzy by Molmil](/molmil-images/mine/5kzy) | |
5KZZ
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![BU of 5kzz by Molmil](/molmil-images/mine/5kzz) | Crystal structure of the xenopus Smoothened cysteine-rich domain (CRD) in its apo-form | Descriptor: | ACETATE ION, GLYCEROL, Smoothened, ... | Authors: | Huang, P, Kim, Y, Salic, A. | Deposit date: | 2016-07-25 | Release date: | 2016-08-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.332 Å) | Cite: | Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling. Cell, 166, 2016
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