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6Y8L

Mycobacterium thermoresistibile GyrB21 in complex with novobiocin

Summary for 6Y8L
Entry DOI10.2210/pdb6y8l/pdb
DescriptorDNA gyrase subunit B, NOVOBIOCIN, ZINC ION, ... (5 entities in total)
Functional Keywordsbinding sites, dna gyrase, inhibitors, novobiocin, topoisomerase iv, isomerase, dna binding protein
Biological sourceMycolicibacterium thermoresistibile
Total number of polymer chains2
Total formula weight43398.86
Authors
Primary citationHenderson, S.R.,Stevenson, C.E.M.,Malone, B.,Zholnerovych, Y.,Mitchenall, L.A.,Pichowicz, M.,McGarry, D.H.,Cooper, I.R.,Charrier, C.,Salisbury, A.M.,Lawson, D.M.,Maxwell, A.
Structural and mechanistic analysis of ATPase inhibitors targeting mycobacterial DNA gyrase.
J.Antimicrob.Chemother., 75:2835-2842, 2020
Cited by
PubMed: 32728686
DOI: 10.1093/jac/dkaa286
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.4 Å)
Structure validation

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