6Y8O
Mycobacterium smegmatis GyrB 22kDa ATPase sub-domain in complex with novobiocin
Summary for 6Y8O
Entry DOI | 10.2210/pdb6y8o/pdb |
Related | 6Y8L 6Y8N |
Descriptor | DNA gyrase subunit B, NOVOBIOCIN, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | binding sites, dna gyrase, inhibitors, , novobiocin iv, isomerase, dna binding protein |
Biological source | Mycolicibacterium smegmatis |
Total number of polymer chains | 2 |
Total formula weight | 54442.51 |
Authors | Henderson, S.R.,Stevenson, C.E.M.,Malone, B.,Zholnerovych, Y.,Mitchenall, L.A.,Pichowicz, M.,McGarry, D.H.,Cooper, I.R.,Charrier, C.,Salisbury, A.,Lawson, D.M.,Maxwell, A. (deposition date: 2020-03-05, release date: 2020-08-12, Last modification date: 2024-01-24) |
Primary citation | Henderson, S.R.,Stevenson, C.E.M.,Malone, B.,Zholnerovych, Y.,Mitchenall, L.A.,Pichowicz, M.,McGarry, D.H.,Cooper, I.R.,Charrier, C.,Salisbury, A.M.,Lawson, D.M.,Maxwell, A. Structural and mechanistic analysis of ATPase inhibitors targeting mycobacterial DNA gyrase. J.Antimicrob.Chemother., 75:2835-2842, 2020 Cited by PubMed: 32728686DOI: 10.1093/jac/dkaa286 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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