Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue NOV A 301 |
| Chain | Residue |
| A | ASN52 |
| A | ARG141 |
| A | HOH403 |
| A | HOH421 |
| A | HOH437 |
| A | HOH467 |
| A | HOH488 |
| A | HOH489 |
| A | HOH516 |
| A | HOH520 |
| A | HOH526 |
| A | GLU56 |
| B | GLY31 |
| B | MET32 |
| A | ASP79 |
| A | ARG82 |
| A | GLY83 |
| A | ILE84 |
| A | PRO85 |
| A | GLU87 |
| A | THR95 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | GLU145 |
| A | GLY162 |
| A | GLU163 |
| A | HOH435 |
| A | HOH538 |
| B | ASP72 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 303 |
| Chain | Residue |
| A | PHE147 |
| A | GLN148 |
| A | TYR149 |
| A | LYS157 |
| A | LYS159 |
| B | ARG134 |
| B | TYR149 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 304 |
| Chain | Residue |
| A | ACT307 |
| A | HOH401 |
| B | ARG192 |
| B | GLN195 |
| B | GLU196 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 305 |
| Chain | Residue |
| A | ARG141 |
| A | ASP142 |
| A | THR167 |
| A | PHE251 |
| A | HIS252 |
| A | TYR253 |
| A | HOH431 |
| A | HOH500 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 306 |
| Chain | Residue |
| A | GLY203 |
| A | HIS252 |
| A | PRO254 |
| A | GLY255 |
| A | HOH530 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue ACT A 307 |
| Chain | Residue |
| A | THR164 |
| A | LYS165 |
| A | EDO304 |
| A | HOH412 |
| B | GLU196 |
| B | TYR253 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue ACT A 308 |
| Chain | Residue |
| A | SER36 |
| A | GLY38 |
| A | GLU39 |
| A | ARG40 |
| A | GLY41 |
| A | HOH406 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 309 |
| Chain | Residue |
| A | ASP80 |
| A | GLY81 |
| A | THR167 |
| A | HOH478 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue NA A 310 |
| Chain | Residue |
| A | GLU136 |
| A | HOH429 |
| B | GLU136 |
| site_id | AD2 |
| Number of Residues | 20 |
| Details | binding site for residue NOV B 301 |
| Chain | Residue |
| A | MET32 |
| A | GLY35 |
| A | HOH483 |
| B | ASN52 |
| B | GLU56 |
| B | ASP79 |
| B | ARG82 |
| B | GLY83 |
| B | ILE84 |
| B | PRO85 |
| B | GLU87 |
| B | VAL99 |
| B | ARG141 |
| B | HOH415 |
| B | HOH429 |
| B | HOH439 |
| B | HOH465 |
| B | HOH494 |
| B | HOH500 |
| B | HOH539 |
| site_id | AD3 |
| Number of Residues | 10 |
| Details | binding site for residue EDO B 302 |
| Chain | Residue |
| B | HOH528 |
| B | HOH556 |
| A | ASP72 |
| B | GLU145 |
| B | GLY162 |
| B | GLU163 |
| B | THR164 |
| B | HOH401 |
| B | HOH414 |
| B | HOH426 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 303 |
| Chain | Residue |
| B | ASP184 |
| B | PHE251 |
| B | HIS252 |
| B | TYR253 |
| B | HOH459 |
| B | HOH506 |
| site_id | AD5 |
| Number of Residues | 9 |
| Details | binding site for residue EDO B 304 |
| Chain | Residue |
| B | TYR33 |
| B | GLU48 |
| B | GLY124 |
| B | VAL127 |
| B | NA310 |
| B | HOH482 |
| B | HOH501 |
| B | HOH548 |
| B | HOH575 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 305 |
| Chain | Residue |
| B | ARG64 |
| B | ASP66 |
| B | ARG78 |
| B | ASP80 |
| site_id | AD7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 306 |
| Chain | Residue |
| B | GLY38 |
| B | GLU39 |
| B | GLU181 |
| B | HIS248 |
| B | VAL250 |
| B | ACT307 |
| B | HOH451 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue ACT B 307 |
| Chain | Residue |
| B | SER36 |
| B | GLY38 |
| B | GLU39 |
| B | ARG40 |
| B | GLY41 |
| B | EDO306 |
| B | HOH451 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue NA B 308 |
| Chain | Residue |
| B | ASP80 |
| B | GLY81 |
| B | THR167 |
| B | HOH570 |
| B | HOH573 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue NA B 309 |
| Chain | Residue |
| B | GLU48 |
| B | HOH444 |
| B | HOH482 |
| B | HOH593 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 310 |
| Chain | Residue |
| A | HOH405 |
| B | TYR33 |
| B | EDO304 |
| B | HOH548 |
| B | HOH571 |
| B | HOH583 |