7UAU
 
 | | The crystal structure of the K137A mutant of E. coli YGGS in complex with PLP | | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, Pyridoxal phosphate homeostasis protein, SULFATE ION | | 著者 | Donkor, A.K, Ghatge, M.S, Musayev, F.N, Safo, M.K. | | 登録日 | 2022-03-14 | | 公開日 | 2022-03-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability.
Protein Sci., 31, 2022
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7UBP
 | | The crystal structure of the K36A/K137A double mutant of E. coli YGGS in complex with PLP | | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, Pyridoxal phosphate homeostasis protein, SULFATE ION | | 著者 | Donkor, A.K, Ghatge, M.S, Musayev, F.N, Safo, M.K. | | 登録日 | 2022-03-15 | | 公開日 | 2022-03-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability.
Protein Sci., 31, 2022
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7UAT
 | | The crystal structure of the K36A mutant of E. coli YGGS in complex with PLP | | 分子名称: | PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, Pyridoxal phosphate homeostasis protein | | 著者 | Donkor, A.K, Ghatge, M.S, Musayev, F.N, Safo, M.K. | | 登録日 | 2022-03-14 | | 公開日 | 2022-03-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability.
Protein Sci., 31, 2022
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7UB8
 | | The crystal structure of the K38A/K137A/K233A/K234A quadruple mutant of E. coli YGGS in complex with PLP | | 分子名称: | 1,4-BUTANEDIOL, PYRIDOXAL-5'-PHOSPHATE, Pyridoxal phosphate homeostasis protein | | 著者 | Donkor, A.K, Ghatge, M.S, Musayev, F.N, Safo, M.K. | | 登録日 | 2022-03-14 | | 公開日 | 2022-03-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability.
Protein Sci., 31, 2022
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7UBQ
 | | The crystal structure of the wild-type of E. coli YGGS in complex with PNP | | 分子名称: | PYRIDOXINE-5'-PHOSPHATE, Pyridoxal phosphate homeostasis protein | | 著者 | Donkor, A.K, Ghatge, M.S, Musayev, F.N, Safo, M.K. | | 登録日 | 2022-03-15 | | 公開日 | 2022-03-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability.
Protein Sci., 31, 2022
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7UD7
 | | Crystal structure of deoxygenated hemoglobin in complex with 5HMF-NO at 1.8 Angstrom | | 分子名称: | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Donkor, A.K, Musayev, F.N, Safo, M.K. | | 登録日 | 2022-03-18 | | 公開日 | 2022-03-30 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Design, Synthesis, and Antisickling Investigation of a Nitric Oxide-Releasing Prodrug of 5HMF for the Treatment of Sickle Cell Disease.
Biomolecules, 12, 2022
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7UF6
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7UB4
 | | The crystal structure of the K36A/K38A/K233A/K234A quadruple mutant of E. coli YGGS in complex with PLP | | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, Pyridoxal phosphate homeostasis protein | | 著者 | Donkor, A.K, Ghatge, M.S, Musayev, F.N, Safo, M.K. | | 登録日 | 2022-03-14 | | 公開日 | 2022-03-30 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability.
Protein Sci., 31, 2022
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7UF7
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4ROM
 | | Deoxyhemoglobin in complex with imidazolylacryloyl derivatives | | 分子名称: | 4-{2-chloro-4-[3-(1H-imidazol-2-yl)propanoyl]phenoxy}butanoic acid, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | | 著者 | Omar, A.M, Mahran, M.A, Ghatge, M.N, Chowdhury, N, Bamane, F.H.A, El-Araby, M.E, Abdulmalik, O, Safo, M.K. | | 登録日 | 2014-10-28 | | 公開日 | 2015-05-20 | | 最終更新日 | 2015-06-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Identification of a novel class of covalent modifiers of hemoglobin as potential antisickling agents.
Org.Biomol.Chem., 13, 2015
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4ROL
 | | Deoxyhemoglobin in complex with imidazolylacryloyl derivatives | | 分子名称: | 4-{2,3-dichloro-4-[3-(1H-imidazol-2-yl)propanoyl]phenoxy}butanoic acid, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | | 著者 | Omar, A.M, Mahran, M.A, Ghatge, M.N, Chowdhury, N, Bamane, F.H.A, El-Araby, M.E, Abdulmalik, O, Safo, M.K. | | 登録日 | 2014-10-28 | | 公開日 | 2015-05-20 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Identification of a novel class of covalent modifiers of hemoglobin as potential antisickling agents.
Org.Biomol.Chem., 13, 2015
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1CEI
 | | STRUCTURE DETERMINATION OF THE COLICIN E7 IMMUNITY PROTEIN (IMME7) THAT BINDS SPECIFICALLY TO THE DNASE-TYPE COLICIN E7 AND INHIBITS ITS BACTERIOCIDAL ACTIVITY | | 分子名称: | COLICIN E7 IMMUNITY PROTEIN | | 著者 | Chak, K.-F, Safo, M.K, Ku, W.-Y, Hsieh, S.-Y, Yuan, H.S. | | 登録日 | 1996-03-19 | | 公開日 | 1997-03-12 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The crystal structure of the immunity protein of colicin E7 suggests a possible colicin-interacting surface.
Proc.Natl.Acad.Sci.USA, 93, 1996
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1RVU
 | | E75Q MUTANT OF RABBIT CYTOSOLIC SERINE HYDROXYMETHYLTRANSFERASE | | 分子名称: | PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, Serine hydroxymethyltransferase, ... | | 著者 | Szebenyi, D.M, Musayev, F.N, Di Salvo, M.L, Safo, M.K, Schirch, V. | | 登録日 | 2003-12-15 | | 公開日 | 2004-06-15 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Serine Hydroxymethyltransferase: Role of Glu75 and Evidence that Serine Is Cleaved by a Retroaldol Mechanism.
Biochemistry, 43, 2004
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1RV4
 | | E75L MUTANT OF RABBIT CYTOSOLIC SERINE HYDROXYMETHYLTRANSFERASE | | 分子名称: | PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, Serine hydroxymethyltransferase, ... | | 著者 | Szebenyi, D.M, Musayev, F.N, Di Salvo, M.L, Safo, M.K, Schirch, V. | | 登録日 | 2003-12-12 | | 公開日 | 2004-06-15 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Serine Hydroxymethyltransferase: Role of Glu75 and Evidence that Serine Is Cleaved by a Retroaldol Mechanism.
Biochemistry, 43, 2004
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1R1X
 | | Crystal structure of oxy-human hemoglobin Bassett at 2.15 angstrom | | 分子名称: | CARBON MONOXIDE, Hemoglobin alpha chain, Hemoglobin beta chain, ... | | 著者 | Abdulmalik, O, Safo, M.K, Lerner, N.B, Ochotorena, J, Dhaikin, Y, Abraham, D.J, Asakura, T. | | 登録日 | 2003-09-25 | | 公開日 | 2003-10-07 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Characterization of hemoglobin bassett (alpha94Asp-->Ala), a variant with very low oxygen affinity
Am.J.Hematol., 77, 2004
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1RVY
 | | E75Q MUTANT OF RABBIT CYTOSOLIC SERINE HYDROXYMETHYLTRANSFERASE, COMPLEX WITH GLYCINE | | 分子名称: | N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Szebenyi, D.M, Musayev, F.N, Di Salvo, M.L, Safo, M.K, Schirch, V. | | 登録日 | 2003-12-15 | | 公開日 | 2004-06-15 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Serine Hydroxymethyltransferase: Role of Glu75 and Evidence that Serine Is Cleaved by a Retroaldol Mechanism.
Biochemistry, 43, 2004
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1R1Y
 | | Crystal structure of deoxy-human hemoglobin Bassett at 1.8 angstrom | | 分子名称: | Hemoglobin alpha chain, Hemoglobin beta chain, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Abdulmalik, O, Safo, M.K, Lerner, N.B, Ochotorena, J, Dhaikin, Y, Abraham, D.J, Asakura, T. | | 登録日 | 2003-09-25 | | 公開日 | 2003-10-07 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Characterization of hemoglobin bassett (alpha94Asp-->Ala), a variant with very low oxygen affinity
Am.J.Hematol., 77, 2004
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1RV3
 | | E75L MUTANT OF RABBIT CYTOSOLIC SERINE HYDROXYMETHYLTRANSFERASE, COMPLEX WITH GLYCINE | | 分子名称: | GLYCINE, PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Szebenyi, D.M, Musayev, F.N, di Salvo, M.L, Safo, M.K, Schirch, V. | | 登録日 | 2003-12-12 | | 公開日 | 2004-06-15 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Serine Hydroxymethyltransferase: Role of Glu75 and Evidence that Serine Is Cleaved by a Retroaldol Mechanism.
Biochemistry, 43, 2004
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