7UB8

The crystal structure of the K38A/K137A/K233A/K234A quadruple mutant of E. coli YGGS in complex with PLP

Summary for 7UB8

• Entry DOI: 10.2210/pdb7ub8/pdb
• Descriptor: Pyridoxal phosphate homeostasis protein, PYRIDOXAL-5'-PHOSPHATE, 1,4-BUTANEDIOL, ... (4 entities in total)
• Functional Keywords: plp-binding protein, vitamin b6, plp homeostasis, protein transport
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 51940.72

Authors

Donkor, A.K.,Ghatge, M.S.,Musayev, F.N.,Safo, M.K. (deposition date: 2022-03-14, release date: 2022-03-23, Last modification date: 2023-10-18)

• Primary citation: Tramonti, A.,Ghatge, M.S.,Babor, J.T.,Musayev, F.N.,di Salvo, M.L.,Barile, A.,Colotti, G.,Giorgi, A.,Paredes, S.D.,Donkor, A.K.,Al Mughram, M.H.,de Crecy-Lagard, V.,Safo, M.K.,Contestabile, R.; Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability.; Protein Sci., 31:e4471-e4471, 2022; PubMed: 36218140; DOI: 10.1002/pro.4471

Experimental method

X-RAY DIFFRACTION (2.3 Å)