7UB4

The crystal structure of the K36A/K38A/K233A/K234A quadruple mutant of E. coli YGGS in complex with PLP

Summary for 7UB4

Entry DOI	10.2210/pdb7ub4/pdb
Descriptor	Pyridoxal phosphate homeostasis protein, PYRIDOXAL-5'-PHOSPHATE (3 entities in total)
Functional Keywords	plp-binding protein, vitamin b6, plp homeostasis, protein transport
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	26082.32
Authors	Donkor, A.K.,Ghatge, M.S.,Musayev, F.N.,Safo, M.K. (deposition date: 2022-03-14, release date: 2022-03-30, Last modification date: 2023-10-18)
Primary citation	Tramonti, A.,Ghatge, M.S.,Babor, J.T.,Musayev, F.N.,di Salvo, M.L.,Barile, A.,Colotti, G.,Giorgi, A.,Paredes, S.D.,Donkor, A.K.,Al Mughram, M.H.,de Crecy-Lagard, V.,Safo, M.K.,Contestabile, R. Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability. Protein Sci., 31:e4471-e4471, 2022 Cited by PubMed: 36218140 DOI: 10.1002/pro.4471 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation