7UF7
Crystal structure of liganded Hb with the 5-HMF analog, MMA503
Summary for 7UF7
Entry DOI | 10.2210/pdb7uf7/pdb |
Descriptor | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE, ... (6 entities in total) |
Functional Keywords | hemoglobin, 5-hmf, sickle cell disease, antisickling, oxygen equilibrium, aromatic aldehydes, oxygen transport |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 65480.20 |
Authors | Donkor, A.K.,Musayev, F.N.,Safo, M.K. (deposition date: 2022-03-22, release date: 2022-03-30, Last modification date: 2024-10-30) |
Primary citation | El-Araby, M.E.,Omar, A.M.,Ghatge, M.S.,Musayev, F.N.,Donkor, A.K.,Paredes, S.D.,Abdulmalik, O.,Safo, M.K. Improving the antisickling activity of furaldehyde To be published, |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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