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7UF6

Crystal structure of liganded Hb with the 5-HMF analog, MMA509

Summary for 7UF6
Entry DOI10.2210/pdb7uf6/pdb
DescriptorHemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE, ... (6 entities in total)
Functional Keywordshemoglobin, 5-hmf, sickle cell disease, antisickling, oxygen equilibrium, aromatic aldehydes, oxygen transport
Biological sourceHomo sapiens (human)
More
Total number of polymer chains4
Total formula weight65516.31
Authors
Donkor, A.K.,Musayev, F.N.,Safo, M.K. (deposition date: 2022-03-22, release date: 2022-03-30, Last modification date: 2024-10-09)
Primary citationEl-Araby, M.E.,Omar, A.M.,Ghatge, M.S.,Musayev, F.N.,Donkor, A.K.,Paredes, S.D.,Abdulmalik, O.,Safo, M.K.
Improving the antisickling activity of furaldehyde
To be published,
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

237423

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