2IFB
 
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2HH7
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4XT7
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4XT6
 | | Crystal structure of Rv2671 from Mycobacterium tuberculosis in complex with the tetrahydropteridine ring of tetrahydrofolate (THF) | | 分子名称: | (6S)-2-amino-6-methyl-5,6,7,8-tetrahydropteridin-4(3H)-one, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Rv2671 | | 著者 | Sacchettini, J.C, Cheng, Y.S, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2015-01-23 | | 公開日 | 2016-02-24 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural Insights into Mycobacterium tuberculosis Rv2671 Protein as a Dihydrofolate Reductase Functional Analogue Contributing to para-Aminosalicylic Acid Resistance.
Biochemistry, 55, 2016
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4XT5
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4XT4
 | | Crystal structure of Rv2671 from Mycobacteirum tuberculosis in complex with dihydropteridine ring of dihydropteroic acid | | 分子名称: | 2-amino-6-methyl-7,8-dihydropteridin-4(3H)-one, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Sacchettini, J.C, Cheng, Y.S, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2015-01-22 | | 公開日 | 2016-02-24 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.891 Å) | | 主引用文献 | Structural Insights into Mycobacterium tuberculosis Rv2671 Protein as a Dihydrofolate Reductase Functional Analogue Contributing to para-Aminosalicylic Acid Resistance.
Biochemistry, 55, 2016
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3F4B
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4XT8
 | | Crystal structure of Rv2671 from Mycobacterium tuberculosis in complex with NADP+ and trimetrexate | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Sacchettini, J.C, Cheng, Y.S, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2015-01-23 | | 公開日 | 2016-02-24 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural Insights into Mycobacterium tuberculosis Rv2671 Protein as a Dihydrofolate Reductase Functional Analogue Contributing to para-Aminosalicylic Acid Resistance.
Biochemistry, 55, 2016
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4R67
 | | Human constitutive 20S proteasome in complex with carfilzomib | | 分子名称: | N-{(2S)-2-[(morpholin-4-ylacetyl)amino]-4-phenylbutanoyl}-L-leucyl-N-[(2R,3S,4S)-1,3-dihydroxy-2,6-dimethylheptan-4-yl]-L-phenylalaninamide, Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, ... | | 著者 | Sacchettini, J.C, Harshbarger, W.H. | | 登録日 | 2014-08-22 | | 公開日 | 2015-02-11 | | 最終更新日 | 2015-02-18 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Crystal Structure of the Human 20S Proteasome in Complex with Carfilzomib.
Structure, 23, 2015
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4R3O
 | | Human Constitutive 20S Proteasome | | 分子名称: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | | 著者 | Sacchettini, J.C, Harshbarger, W.H. | | 登録日 | 2014-08-16 | | 公開日 | 2015-01-28 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of the Human 20S Proteasome in Complex with Carfilzomib.
Structure, 23, 2015
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3OKR
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1IFB
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1M1M
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1EIO
 | | ILEAL LIPID BINDING PROTEIN IN COMPLEX WITH GLYCOCHOLATE | | 分子名称: | GLYCOCHOLIC ACID, ILEAL LIPID BINDING PROTEIN | | 著者 | Luecke, C, Zhang, F, Hamilton, J.A, Sacchettini, J.C, Rueterjans, H. | | 登録日 | 2000-02-27 | | 公開日 | 2000-05-31 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of ileal lipid binding protein in complex with glycocholate.
Eur.J.Biochem., 267, 2000
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1MAS
 | | PURINE NUCLEOSIDE HYDROLASE | | 分子名称: | INOSINE-URIDINE NUCLEOSIDE N-RIBOHYDROLASE, POTASSIUM ION | | 著者 | Degano, M, Gopaul, D.N, Scapin, G, Schramm, V.L, Sacchettini, J.C. | | 登録日 | 1995-12-18 | | 公開日 | 1996-08-17 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Three-dimensional structure of the inosine-uridine nucleoside N-ribohydrolase from Crithidia fasciculata.
Biochemistry, 35, 1996
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4UBE
 | | CRYSTAL STRUCTURE OF M TUBERCULOSIS ADENOSINE KINASE COMPLEXED WITH 2-FLURO ADENOSINE | | 分子名称: | 2-(6-AMINO-2-FLUORO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, Adenosine kinase | | 著者 | Reddy, M.C.M, Palaninathan, S.K, Shetty, N.D, Owen, J.L, Watson, M.D, Sacchettini, J.C. | | 登録日 | 2014-08-12 | | 公開日 | 2014-09-24 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.933 Å) | | 主引用文献 | CRYSTAL STRUCTURE OF M TUBERCULOSIS ADENOSINE KINASE COMPLEXED WITH 2-FLURO ADENOSINE
TO BE PUBLISHED
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6DKO
 | | Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 2,6-F-phenyldiketoacid | | 分子名称: | 4-(2,6-difluorophenyl)-2,4-dioxobutanoic acid, MAGNESIUM ION, Malate synthase G | | 著者 | Krieger, I.V, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2018-05-30 | | 公開日 | 2018-09-05 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.556 Å) | | 主引用文献 | Anion-pi Interactions in Computer-Aided Drug Design: Modeling the Inhibition of Malate Synthase by Phenyl-Diketo Acids.
J Chem Inf Model, 58, 2018
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6DNP
 | | Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 2-F-3-Methyl-6-F-phenyldiketoacid | | 分子名称: | (2Z)-4-(2,6-difluoro-3-methylphenyl)-2-hydroxy-4-oxobut-2-enoic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, ... | | 著者 | Krieger, I.V, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC), Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) | | 登録日 | 2018-06-07 | | 公開日 | 2018-09-05 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.711 Å) | | 主引用文献 | Anion-pi Interactions in Computer-Aided Drug Design: Modeling the Inhibition of Malate Synthase by Phenyl-Diketo Acids.
J Chem Inf Model, 58, 2018
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3VFH
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3VFF
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2SBA
 | | SOYBEAN AGGLUTININ COMPLEXED WITH 2,6-PENTASACCHARIDE | | 分子名称: | CALCIUM ION, Lectin, MANGANESE (II) ION, ... | | 著者 | Dessen, A, Gupta, D, Sabesan, S, Brewer, C.F, Sacchettini, J.C. | | 登録日 | 1998-12-03 | | 公開日 | 1998-12-09 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | X-ray crystal structure of the soybean agglutinin cross-linked with a biantennary analog of the blood group I carbohydrate antigen.
Biochemistry, 34, 1995
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1MTO
 | | Crystal structure of a Phosphofructokinase mutant from Bacillus stearothermophilus bound with fructose-6-phosphate | | 分子名称: | 6-O-phosphono-beta-D-fructofuranose, 6-phosphofructokinase | | 著者 | Riley-Lovingshimer, M.R, Ronning, D.R, Sacchettini, J.C, Reinhart, G.D. | | 登録日 | 2002-09-21 | | 公開日 | 2002-12-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Reversible Ligand-Induced Dissociation of a Tryptophan-Shift Mutant of Phosphofructokinase
from Bacillus stearothermophilus
Biochemistry, 41, 2002
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8GKF
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4P4N
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3D2T
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