3F4B

Crystal structure of Plasmodium berghei Enoyl-acyl-carrier-protein reductase with TRICLOSAN

Summary for 3F4B

• Entry DOI: 10.2210/pdb3f4b/pdb
• Related: 1NHG
• Descriptor: Enoyl-acyl carrier protein reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN, ... (4 entities in total)
• Functional Keywords: pbenr, pbfabi, triclosan, oxidoreductase
• Biological source: Plasmodium berghei
• Total number of polymer chains: 4
• Total formula weight: 147529.21

Authors

Sacchettini, J.C.,Tsai, H.-C. (deposition date: 2008-10-31, release date: 2010-03-02, Last modification date: 2023-09-06)

• Primary citation: Yu, M.,Kumar, T.R.,Nkrumah, L.J.,Coppi, A.,Retzlaff, S.,Li, C.D.,Kelly, B.J.,Moura, P.A.,Lakshmanan, V.,Freundlich, J.S.,Valderramos, J.C.,Vilcheze, C.,Siedner, M.,Tsai, J.H.,Falkard, B.,Sidhu, A.B.,Purcell, L.A.,Gratraud, P.,Kremer, L.,Waters, A.P.,Schiehser, G.,Jacobus, D.P.,Janse, C.J.,Ager, A.,Jacobs, W.R.,Sacchettini, J.C.,Heussler, V.,Sinnis, P.,Fidock, D.A.; The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites.; Cell Host Microbe, 4:567-578, 2008; PubMed: 19064257; DOI: 10.1016/j.chom.2008.11.001

Experimental method

X-RAY DIFFRACTION (2.49 Å)