1M1M
X-RAY CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III (MTFABH)
Summary for 1M1M
Entry DOI | 10.2210/pdb1m1m/pdb |
Descriptor | 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE III (2 entities in total) |
Functional Keywords | 3-oxoacyl-acyl carrier protein synthase iii, mtfabh, condensing enzyme, alpha-beta-alpha-beta-alpha, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc, transferase |
Biological source | Mycobacterium tuberculosis |
Cellular location | Cytoplasm: P0A574 |
Total number of polymer chains | 2 |
Total formula weight | 74149.49 |
Authors | Sacchettini, J.C.,Sridharan, S.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2002-06-19, release date: 2002-07-17, Last modification date: 2024-02-14) |
Primary citation | Brown, A.K.,Sridharan, S.,Kremer, L.,Lindenberg, S.,Dover, L.G.,Sacchettini, J.C.,Besra, G.S. Probing the mechanism of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III mtFabH: factors influencing catalysis and substrate specificity. J.Biol.Chem., 280:32539-32547, 2005 Cited by PubMed: 16040614DOI: 10.1074/jbc.M413216200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
Download full validation report