4R3O
Human Constitutive 20S Proteasome
Summary for 4R3O
Entry DOI | 10.2210/pdb4r3o/pdb |
Related | 1IRU 1PMA 1RYP 3UNE 4R67 |
Descriptor | Proteasome subunit alpha type-6, Proteasome subunit beta type-3, Proteasome subunit beta type-2, ... (15 entities in total) |
Functional Keywords | hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P60900 P49720 P49721 P28074 P20618 P28070 P25787 P25789 O14818 P28066 P25786 P25788 P28072 Q99436 |
Total number of polymer chains | 28 |
Total formula weight | 697897.01 |
Authors | Sacchettini, J.C.,Harshbarger, W.H. (deposition date: 2014-08-16, release date: 2015-01-28, Last modification date: 2024-02-28) |
Primary citation | Harshbarger, W.,Miller, C.,Diedrich, C.,Sacchettini, J. Crystal Structure of the Human 20S Proteasome in Complex with Carfilzomib. Structure, 23:418-424, 2015 Cited by PubMed: 25599644DOI: 10.1016/j.str.2014.11.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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