5LRE
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![BU of 5lre by Molmil](/molmil-images/mine/5lre) | Crystal structure of Glycogen Phosphorylase b in complex with KS382 | Descriptor: | (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(3-naphthalen-2-yl-1~{H}-1,2,4-triazol-5-yl)oxane-3,4,5-triol, DIMETHYL SULFOXIDE, Glycogen phosphorylase, ... | Authors: | Kantsadi, A.L, Stravodimos, G.A, Kyriakis, E, Chatzileontiadou, D.S.M, Leonidas, D.D. | Deposit date: | 2016-08-18 | Release date: | 2017-05-31 | Last modified: | 2018-01-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Synthetic, enzyme kinetic, and protein crystallographic studies of C-beta-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase. Eur J Med Chem, 123, 2016
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5LRW
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![BU of 5lrw by Molmil](/molmil-images/mine/5lrw) | Structure of Cezanne/OTUD7B OTU domain bound to ubiquitin | Descriptor: | GLYCEROL, OTU domain-containing protein 7B, Polyubiquitin-B | Authors: | Mevissen, T.E.T, Kulathu, Y, Mulder, M.P.C, Geurink, P.P, Maslen, S.L, Gersch, M, Elliott, P.R, Burke, J.E, van Tol, B.D.M, Akutsu, M, El Oualid, F, Kawasaki, M, Freund, S.M.V, Ovaa, H, Komander, D. | Deposit date: | 2016-08-22 | Release date: | 2016-10-19 | Last modified: | 2017-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne. Nature, 538, 2016
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3TZR
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![BU of 3tzr by Molmil](/molmil-images/mine/3tzr) | Structure of a Riboswitch-like RNA-ligand complex from the Hepatitis C Virus Internal Ribosome Entry Site | Descriptor: | (8R)-8-[(dimethylamino)methyl]-1-[3-(dimethylamino)propyl]-1,7,8,9-tetrahydrochromeno[5,6-d]imidazol-2-amine, 5'-R(*CP*GP*AP*GP*GP*AP*AP*CP*UP*AP*CP*UP*GP*UP*CP*UP*UP*CP*CP*C)-3', 5'-R(*GP*GP*UP*CP*GP*UP*GP*CP*AP*GP*CP*CP*UP*CP*GP*G)-3', ... | Authors: | Dibrov, S.M, Ding, K, Brunn, N, Parker, M.A, Bergdahl, B.M, Wyles, D.L, Hermann, T. | Deposit date: | 2011-09-27 | Release date: | 2012-03-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.212 Å) | Cite: | Structure of a Riboswitch in the Hepatitis C Virus Internal Ribosome Entry Site To be Published
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3IOX
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![BU of 3iox by Molmil](/molmil-images/mine/3iox) | Crystal Structure of A3VP1 of AgI/II of Streptococcus mutans | Descriptor: | AgI/II, CALCIUM ION, SULFITE ION, ... | Authors: | Larson, M.R, Rajashankar, K.R, Patel, M, Robinette, R, Crowley, P, Michalek, S.M, Brady, L.J, Deivanayagam, C.C. | Deposit date: | 2009-08-14 | Release date: | 2010-04-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Elongated fibrillar structure of a streptococcal adhesin assembled by the high-affinity association of alpha- and PPII-helices. Proc.Natl.Acad.Sci.USA, 107, 2010
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3IPK
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![BU of 3ipk by Molmil](/molmil-images/mine/3ipk) | Crystal Structure of A3VP1 of AgI/II of Streptococcus mutans | Descriptor: | AgI/II, CALCIUM ION, SULFATE ION, ... | Authors: | Larson, M.R, Rajashankar, K.R, Patel, M, Robinette, R, Crowley, P, Michalek, S.M, Brady, L.J, Deivanayagam, C.C. | Deposit date: | 2009-08-17 | Release date: | 2010-03-31 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Elongated fibrillar structure of a streptococcal adhesin assembled by the high-affinity association of alpha- and PPII-helices. Proc.Natl.Acad.Sci.USA, 107, 2010
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3UF1
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![BU of 3uf1 by Molmil](/molmil-images/mine/3uf1) | Crystal Structure of Vimentin (fragment 144-251) from Homo sapiens, Northeast Structural Genomics Consortium Target HR4796B | Descriptor: | Vimentin | Authors: | Kuzin, A, Abashidze, M, Vorobiev, S.M, Patel, P, Xiao, R, Ciccosanti, C, Shastry, R, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2011-10-31 | Release date: | 2011-11-30 | Last modified: | 2013-04-24 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | The structure of vimentin linker 1 and rod 1B domains characterized by site-directed spin-labeling electron paramagnetic resonance (SDSL-EPR) and X-ray crystallography. J.Biol.Chem., 287, 2012
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3I7I
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![BU of 3i7i by Molmil](/molmil-images/mine/3i7i) | MMP-13 in complex with a non zinc-chelating inhibitor | Descriptor: | CALCIUM ION, Collagenase 3, N-[4-(5-{[(1S)-1-cyclohexyl-2-(methylamino)-2-oxoethyl]carbamoyl}furan-2-yl)phenyl]-1-benzofuran-2-carboxamide, ... | Authors: | Farrow, N.A, Margarit, S.M. | Deposit date: | 2009-07-08 | Release date: | 2009-09-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.208 Å) | Cite: | Improving potency and selectivity of a new class of non-Zn-chelating MMP-13 inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
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5BPA
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![BU of 5bpa by Molmil](/molmil-images/mine/5bpa) | |
3TY0
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![BU of 3ty0 by Molmil](/molmil-images/mine/3ty0) | Structure of PPARgamma ligand binding domain in complex with (R)-5-(3-((3-(6-methoxybenzo[d]isoxazol-3-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)methyl)phenyl)-5-methyloxazolidine-2,4-dione | Descriptor: | (5R)-5-(3-{[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl]methyl}phenyl)-5-methyl-1,3-oxazolidine-2,4-dione, Peroxisome proliferator-activated receptor gamma | Authors: | Soisson, S.M, Meinke, P.M, McKeever, B, Liu, W. | Deposit date: | 2011-09-23 | Release date: | 2011-11-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Benzimidazolones: a new class of selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) modulators. J.Med.Chem., 54, 2011
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2KI4
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![BU of 2ki4 by Molmil](/molmil-images/mine/2ki4) | |
1BB5
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![BU of 1bb5 by Molmil](/molmil-images/mine/1bb5) | |
1HWG
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![BU of 1hwg by Molmil](/molmil-images/mine/1hwg) | |
3FEY
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![BU of 3fey by Molmil](/molmil-images/mine/3fey) | |
5TXL
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![BU of 5txl by Molmil](/molmil-images/mine/5txl) | STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING DATP | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG) P*CP*GP*CP*CP*GP)-3'), ... | Authors: | Das, K, Martinez, S.M, Arnold, E. | Deposit date: | 2016-11-17 | Release date: | 2017-04-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Structural Insights into HIV Reverse Transcriptase Mutations Q151M and Q151M Complex That Confer Multinucleoside Drug Resistance. Antimicrob. Agents Chemother., 61, 2017
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5U0K
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![BU of 5u0k by Molmil](/molmil-images/mine/5u0k) | C-terminal ankyrin repeats from human liver-type glutaminase (GAB/LGA) | Descriptor: | Glutaminase liver isoform, mitochondrial | Authors: | Ferreira, I.M, Pasquali, C.C, Gonzalez, A, Dias, S.M.G, Ambrosio, A.L.B. | Deposit date: | 2016-11-24 | Release date: | 2017-05-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.548 Å) | Cite: | The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats. J. Biol. Chem., 292, 2017
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6S4M
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![BU of 6s4m by Molmil](/molmil-images/mine/6s4m) | Crystal structure of the human organic anion transporter MFSD10 (TETRAN) | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CITRIC ACID, Major facilitator superfamily domain-containing protein 10 | Authors: | Pascoa, T.C, Pike, A.C.W, Bushell, S.R, Quigley, A, Chu, A, Mukhopadhyay, S.M.M, Shrestha, L, Venkaya, S, Chalk, R, Burgess-Brown, N.A, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | Deposit date: | 2019-06-28 | Release date: | 2020-05-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the human organic anion transporter TETRAN (MFSD10) To be published
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2KVN
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![BU of 2kvn by Molmil](/molmil-images/mine/2kvn) | Phi29 E-loop hairpin | Descriptor: | RNA (5'-R(*GP*GP*UP*GP*AP*UP*UP*GP*AP*GP*UP*UP*CP*AP*CP*CP*A)-3') | Authors: | Harris, S.M, Schroeder, S.J. | Deposit date: | 2010-03-19 | Release date: | 2010-07-07 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Nuclear magnetic resonance structure of the prohead RNA E-loop hairpin. Biochemistry, 49, 2010
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5TXM
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![BU of 5txm by Molmil](/molmil-images/mine/5txm) | STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING DDATP | Descriptor: | 1,2-ETHANEDIOL, 2',3'-dideoxyadenosine triphosphate, DNA (5'-D(*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*G)-3'), ... | Authors: | Das, K, Martinez, S.M, Arnold, E. | Deposit date: | 2016-11-17 | Release date: | 2017-04-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Insights into HIV Reverse Transcriptase Mutations Q151M and Q151M Complex That Confer Multinucleoside Drug Resistance. Antimicrob. Agents Chemother., 61, 2017
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5U0I
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![BU of 5u0i by Molmil](/molmil-images/mine/5u0i) | C-terminal ankyrin repeats from human kidney-type glutaminase (KGA) - tetragonal crystal form | Descriptor: | CHLORIDE ION, Glutaminase kidney isoform, mitochondrial, ... | Authors: | Pasquali, C.C, Gonzalez, A, Dias, S.M.G, Ambrosio, A.L.B. | Deposit date: | 2016-11-24 | Release date: | 2017-05-24 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.423 Å) | Cite: | The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats. J. Biol. Chem., 292, 2017
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3GWS
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![BU of 3gws by Molmil](/molmil-images/mine/3gws) | Crystal Structure of T3-Bound Thyroid Hormone Receptor | Descriptor: | 3,5,3'TRIIODOTHYRONINE, Thyroid hormone receptor beta | Authors: | Nascimento, A.S, Dias, S.M.G, Nunes, F.M, Aparicio, R, Polikarpov, I, Baxter, J.D, Webb, P. | Deposit date: | 2009-04-01 | Release date: | 2009-04-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function J.Mol.Biol., 360, 2006
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8D7M
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![BU of 8d7m by Molmil](/molmil-images/mine/8d7m) | Human Casein kinase 1 delta in complex with phosphorylated human PERIOD2 FASP peptide | Descriptor: | Casein kinase I isoform delta, Period circadian protein homolog 2 peptide | Authors: | Philpott, J.M, Freeberg, A.M, Tripathi, S.M, Partch, C.L. | Deposit date: | 2022-06-07 | Release date: | 2023-05-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period. Mol.Cell, 83, 2023
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8D7O
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![BU of 8d7o by Molmil](/molmil-images/mine/8d7o) | Human Casein kinase 1 delta in complex with phosphorylated human PERIOD2 FASP peptide | Descriptor: | Casein kinase I isoform delta, Period circadian protein homolog 2 peptide | Authors: | Philpott, J.M, Freeberg, A.M, Tripathi, S.M, Partch, C.L. | Deposit date: | 2022-06-07 | Release date: | 2023-05-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period. Mol.Cell, 83, 2023
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8D7P
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![BU of 8d7p by Molmil](/molmil-images/mine/8d7p) | Human Casein kinase 1 delta in complex with phosphorylated Drosophila PERIOD peptide | Descriptor: | Casein kinase I isoform delta, Period circadian protein peptide | Authors: | Philpott, J.M, Freeberg, A.M, Tripathi, S.M, Partch, C.L. | Deposit date: | 2022-06-07 | Release date: | 2023-05-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period. Mol.Cell, 83, 2023
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8D7N
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![BU of 8d7n by Molmil](/molmil-images/mine/8d7n) | Human Casein kinase 1 delta in complex with phosphorylated human PERIOD2 FASP peptide | Descriptor: | Casein kinase I isoform delta, Period circadian protein homolog 2 peptide | Authors: | Philpott, J.M, Freeberg, A.M, Tripathi, S.M, Partch, C.L. | Deposit date: | 2022-06-07 | Release date: | 2023-05-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period. Mol.Cell, 83, 2023
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6SWG
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![BU of 6swg by Molmil](/molmil-images/mine/6swg) | |