5LRE
Crystal structure of Glycogen Phosphorylase b in complex with KS382
Summary for 5LRE
Entry DOI | 10.2210/pdb5lre/pdb |
Related | 5LRD |
Descriptor | Glycogen phosphorylase, muscle form, (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(3-naphthalen-2-yl-1~{H}-1,2,4-triazol-5-yl)oxane-3,4,5-triol, PYRIDOXAL-5'-PHOSPHATE, ... (5 entities in total) |
Functional Keywords | transferase, alpha and beta protein |
Biological source | Oryctolagus cuniculus (Rabbit) |
Total number of polymer chains | 1 |
Total formula weight | 98409.33 |
Authors | Kantsadi, A.L.,Stravodimos, G.A.,Kyriakis, E.,Chatzileontiadou, D.S.M.,Leonidas, D.D. (deposition date: 2016-08-18, release date: 2017-05-31, Last modification date: 2018-01-17) |
Primary citation | Kantsadi, A.L.,Bokor, E.,Kun, S.,Stravodimos, G.A.,Chatzileontiadou, D.S.,Leonidas, D.D.,Juhasz-Toth, E.,Szakacs, A.,Batta, G.,Docsa, T.,Gergely, P.,Somsak, L. Synthetic, enzyme kinetic, and protein crystallographic studies of C-beta-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase. Eur J Med Chem, 123:737-745, 2016 Cited by PubMed: 27522507DOI: 10.1016/j.ejmech.2016.06.049 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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