Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 119 件

8FFF
DownloadVisualize
BU of 8fff by Molmil
Crystal structure of Staphylococcus aureus D-alanine D-alanine ligase enzyme in complex with acetate
分子名称: ACETATE ION, D-alanine--D-alanine ligase
著者Jayasinghe, Y.P, Ronning, D.R.
登録日2022-12-08
公開日2024-05-08
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Staphylococcus aureus counters organic acid anion-mediated inhibition of peptidoglycan cross-linking through robust alanine racemase activity.
Biorxiv, 2024
1NL3
DownloadVisualize
BU of 1nl3 by Molmil
CRYSTAL STRUCTURE OF THE SECA PROTEIN TRANSLOCATION ATPASE FROM MYCOBACTERIUM TUBERCULOSIS in APO FORM
分子名称: PREPROTEIN TRANSLOCASE SECA 1 SUBUNIT
著者Sharma, V, Arockiasamy, A, Ronning, D.R, Savva, C.G, Holzenburg, A, Braunstein, M, Jacobs Jr, W.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2003-01-06
公開日2003-03-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of M. tuberculosis SecA, A Preprotein Translocating ATPase
Proc.Natl.Acad.Sci.USA, 100, 2003
8GLB
DownloadVisualize
BU of 8glb by Molmil
Selenomethionine Derivatized Citrate Synthase (CitA) in Mycobacterium tuberculosis with Pyruvate
分子名称: 1,2-ETHANEDIOL, PYRUVIC ACID, citrate synthase
著者Pathirage, R, Ronning, D, Favrot, L.
登録日2023-03-21
公開日2023-06-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
8GMI
DownloadVisualize
BU of 8gmi by Molmil
Citrate Synthase (CitA) in Mycobacterium tuberculosis modified by Ebselen at C143 residue
分子名称: CITRATE ANION, N-phenyl-2-selanylbenzamide, citrate synthase
著者Pathirage, R, Ronning, D.
登録日2023-03-25
公開日2023-06-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
8GMK
DownloadVisualize
BU of 8gmk by Molmil
Pyruvate bound structure of Citrate Synthase (CitA) in Mycobacterium Tuberculosis
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PYRUVIC ACID, ...
著者Pathirage, R, Ronning, D, Yamsek, M.
登録日2023-03-26
公開日2023-06-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
8GI7
DownloadVisualize
BU of 8gi7 by Molmil
C143A variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis
分子名称: 1,2-ETHANEDIOL, CITRATE ANION, citrate synthase (unknown stereospecificity)
著者Pathirage, R, Ronning, D.
登録日2023-03-13
公開日2023-06-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
8GM9
DownloadVisualize
BU of 8gm9 by Molmil
Structure of Citrate Synthase(CitA) in Mycobacterium Tuberculosis
分子名称: 1,2-ETHANEDIOL, ACRYLIC ACID, DI(HYDROXYETHYL)ETHER, ...
著者Pathirage, R, Ronning, D, Favrot, L.
登録日2023-03-24
公開日2023-06-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
8GLL
DownloadVisualize
BU of 8gll by Molmil
R149E variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, SULFATE ION, ...
著者Pathirage, R, Ronning, D, Petit, C.
登録日2023-03-22
公開日2023-06-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
8GIW
DownloadVisualize
BU of 8giw by Molmil
C143K variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis
分子名称: 1,2-ETHANEDIOL, CITRATE ANION, DI(HYDROXYETHYL)ETHER, ...
著者Pathirage, R, Ronning, D.
登録日2023-03-14
公開日2023-06-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
8GMF
DownloadVisualize
BU of 8gmf by Molmil
R153M variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis
分子名称: citrate synthase
著者Pathirage, R, Ronning, D.
登録日2023-03-25
公開日2023-06-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
5JPC
DownloadVisualize
BU of 5jpc by Molmil
Joint X-ray/neutron structure of MTAN complex with Formycin A
分子名称: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, Aminodeoxyfutalosine nucleosidase
著者Banco, M.T, Kovalevsky, A.Y, Ronning, D.R.
登録日2016-05-03
公開日2016-11-16
最終更新日2024-03-06
実験手法NEUTRON DIFFRACTION (2.5 Å), X-RAY DIFFRACTION
主引用文献Neutron structures of the Helicobacter pylori 5'-methylthioadenosine nucleosidase highlight proton sharing and protonation states.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
1RZ9
DownloadVisualize
BU of 1rz9 by Molmil
Crystal Structure of AAV Rep complexed with the Rep-binding sequence
分子名称: 26-MER, Rep protein
著者Hickman, A.B, Ronning, D.R, Perez, Z.N, Kotin, R.M, Dyda, F.
登録日2003-12-24
公開日2004-02-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The nuclease domain of adeno-associated virus rep coordinates replication initiation using two distinct DNA recognition interfaces.
Mol.Cell, 13, 2004
5KB3
DownloadVisualize
BU of 5kb3 by Molmil
1.4 A resolution structure of Helicobacter Pylori MTAN in complexed with p-ClPh-DADMe-ImmA
分子名称: (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-{[(4-chlorophenyl)sulfanyl]methyl}pyrrolidin-3-ol, Aminodeoxyfutalosine nucleosidase, MAGNESIUM ION
著者Banco, M.T, Ronning, D.R.
登録日2016-06-02
公開日2016-11-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.399 Å)
主引用文献Neutron structures of the Helicobacter pylori 5'-methylthioadenosine nucleosidase highlight proton sharing and protonation states.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
2VJU
DownloadVisualize
BU of 2vju by Molmil
Crystal structure of the IS608 transposase in complex with the complete Right end 35-mer DNA and manganese
分子名称: MANGANESE (II) ION, RIGHT END 35-MER, TRANSPOSASE ORFA
著者Barabas, O, Ronning, D.R, Guynet, C, Hickman, A.B, Ton-Hoang, B, Chandler, M, Dyda, F.
登録日2007-12-13
公開日2008-02-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Mechanism of is200/is605 Family DNA Transposases: Activation and Transposon-Directed Target Site Selection.
Cell(Cambridge,Mass.), 132, 2008
5VT4
DownloadVisualize
BU of 5vt4 by Molmil
Sco GlgEI-V279S in complex with a pyrolidene-based methyl-phosphonate compound
分子名称: Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase 1, {[(2R,3R,4R,5R)-3-(alpha-D-glucopyranosyloxy)-4-hydroxy-2,5-bis(hydroxymethyl)pyrrolidin-1-yl]methyl}phosphonic acid
著者Petit, C, Ronning, D.R, Lindenberger, J.J.
登録日2017-05-15
公開日2017-06-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.205 Å)
主引用文献Zwitterionic pyrrolidene-phosphonates: inhibitors of the glycoside hydrolase-like phosphorylase Streptomyces coelicolor GlgEI-V279S.
Org. Biomol. Chem., 15, 2017
2VIC
DownloadVisualize
BU of 2vic by Molmil
CRYSTAL STRUCTURE OF THE ISHP608 TRANSPOSASE IN COMPLEX with Left end 26- mer DNA and manganese
分子名称: 5'-D(*AP*AP*AP*GP*CP*CP*CP*CP*TP*AP *GP*CP*TP*TP*TP*TP*AP*GP*CP*TP*AP*TP*GP*GP*GP*G)-3', MANGANESE (II) ION, TRANSPOSASE ORFA
著者Barabas, O, Ronning, D.R, Guynet, C, Hickman, A.B, Ton-Hoang, B, Chandler, M, Dyda, F.
登録日2007-11-29
公開日2008-02-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Mechanism of is200/is605 Family DNA Transposases: Activation and Transposon-Directed Target Site Selection.
Cell(Cambridge,Mass.), 132, 2008
2VHG
DownloadVisualize
BU of 2vhg by Molmil
Crystal Structure of the ISHp608 Transposase in Complex with Right End 31-mer DNA
分子名称: MANGANESE (II) ION, RIGHT END 31-MER, TRANSPOSASE ORFA
著者Barabas, O, Ronning, D.R, Guynet, C, Hickman, A.B, Ton-Hoang, B, Chandler, M, Dyda, F.
登録日2007-11-21
公開日2008-02-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Mechanism of is200/is605 Family DNA Transposases: Activation and Transposon-Directed Target Site Selection.
Cell(Cambridge,Mass.), 132, 2008
2VIH
DownloadVisualize
BU of 2vih by Molmil
CRYSTAL STRUCTURE OF THE IS608 TRANSPOSASE IN COMPLEX WITH Left END 26-MER DNA
分子名称: 5'-D(*AP*AP*AP*GP*CP*CP*CP*CP*TP*AP *GP*CP*TP*TP*TP*TP*AP*GP*CP*TP*AP*TP*GP*GP*GP*G)-3', TRANSPOSASE ORFA
著者Barabas, O, Ronning, D.R, Guynet, C, Hickman, A.B, Ton-Hoang, B, Chandler, M, Dyda, F.
登録日2007-12-04
公開日2008-02-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mechanism of is200/is605 Family DNA Transposases: Activation and Transposon-Directed Target Site Selection.
Cell(Cambridge,Mass.), 132, 2008
5KWJ
DownloadVisualize
BU of 5kwj by Molmil
M.tb Ag85C modified at C209 by amino-ebselen
分子名称: Diacylglycerol acyltransferase/mycolyltransferase Ag85C, ~{N}-(4-aminophenyl)-2-selanyl-benzamide
著者Goins, C.M, Ronning, D.R.
登録日2016-07-18
公開日2017-03-29
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Exploring Covalent Allosteric Inhibition of Antigen 85C from Mycobacterium tuberculosis by Ebselen Derivatives.
ACS Infect Dis, 3, 2017
5VNS
DownloadVisualize
BU of 5vns by Molmil
M.tb Antigen 85C Acyl-Enzyme Intermediate with Tetrahydrolipstatin
分子名称: (2S,3S,5S)-5-[(N-FORMYL-L-LEUCYL)OXY]-2-HEXYL-3-HYDROXYHEXADECANOIC ACID, (4S)-2-METHYL-2,4-PENTANEDIOL, Diacylglycerol acyltransferase/mycolyltransferase Ag85C, ...
著者Goins, C.M, Ronning, D.R.
登録日2017-05-01
公開日2018-01-24
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Mycolyltransferase fromMycobacterium tuberculosisin covalent complex with tetrahydrolipstatin provides insights into antigen 85 catalysis.
J. Biol. Chem., 293, 2018
2VJV
DownloadVisualize
BU of 2vjv by Molmil
Crystal structure of the IS608 transposase in complex with left end 26-mer DNA hairpin and a 6-mer DNA representing the left end cleavage site
分子名称: 5'-D(*DA*DA*DA*DG*DC*DC*DC*DC*DT*DA*DG*DC*DTP*DT *DT*DT*DA*DG*DC*DT*DA*DT*DG*DG*DG*DGP)-3', 5'-D(*DT*DA*DT*DT*DA*DCP)-3', MAGNESIUM ION, ...
著者Barabas, O, Ronning, D.R, Guynet, C, Hickman, A.B, Ton-Hoang, B, Chandler, M, Dyda, F.
登録日2007-12-13
公開日2008-02-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanism of is200/is605 Family DNA Transposases: Activation and Transposon-Directed Target Site Selection.
Cell(Cambridge,Mass.), 132, 2008
1YNK
DownloadVisualize
BU of 1ynk by Molmil
Identification of Key residues of the NC6.8 Fab antibody fragment binding to synthetic sweeteners: Crystal structure of NC6.8 co-crystalized with high potency sweetener compound SC45647
分子名称: 2-[((R)-{[4-(AMINOMETHYL)PHENYL]AMINO}{[(1R)-1-PHENYLETHYL]AMINO}METHYL)AMINO]ETHANE-1,1-DIOL, Ig gamma heavy chain, immunoglobulin kappa light chain
著者Gokulan, K, Khare, S, Ronning, D.R, Linthicum, S.D, Sacchettini, J.C, Rupp, B.
登録日2005-01-24
公開日2005-08-16
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Cocrystal Structures of NC6.8 Fab Identify Key Interactions for High Potency Sweetener Recognition: Implications for the Design of Synthetic Sweeteners
Biochemistry, 44, 2005
5K1Z
DownloadVisualize
BU of 5k1z by Molmil
Joint X-ray/neutron structure of MTAN complex with p-ClPh-Thio-DADMe-ImmA
分子名称: (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-{[(4-chlorophenyl)sulfanyl]methyl}pyrrolidin-3-ol, Aminodeoxyfutalosine nucleosidase
著者Banco, M.T, Kovalevsky, A.Y, Ronning, D.R.
登録日2016-05-18
公開日2016-11-16
最終更新日2024-03-06
実験手法NEUTRON DIFFRACTION (2.6 Å), X-RAY DIFFRACTION
主引用文献Neutron structures of the Helicobacter pylori 5'-methylthioadenosine nucleosidase highlight proton sharing and protonation states.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
4MQM
DownloadVisualize
BU of 4mqm by Molmil
Crystal structure of Antigen 85C in presence of Ebselen
分子名称: Diacylglycerol acyltransferase/mycolyltransferase Ag85C
著者Favrot, L, Grzegorzewicz, A.E, Lajiness, D.H, Marvin, R.K, Boucau, J, Isailovic, D, Jackson, M, Ronning, D.R.
登録日2013-09-16
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.346 Å)
主引用文献Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen.
Nat Commun, 4, 2013
1UUT
DownloadVisualize
BU of 1uut by Molmil
The Nuclease Domain of Adeno-Associated Virus Rep Complexed with the RBE' Stemloop of the Viral Inverted Terminal Repeat
分子名称: 5'-D(*CP*AP*GP*CP*TP*CP*TP*TP*TP*GP *AP*GP*CP*TP*G)-3', CHLORIDE ION, MAGNESIUM ION, ...
著者Dyda, F, Hickman, A.B, Ronning, D.R, Perez, Z.N, Kotin, R.M.
登録日2004-01-10
公開日2004-02-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Nuclease Domain of Adeno-Associated Virus Rep Coordinates Replication Initiation Using Two Distinct DNA Recognition Interfaces
Mol.Cell, 13, 2004

222624

件を2024-07-17に公開中

PDB statisticsPDBj update infoContact PDBjnumon