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PDB: 227 件

8PJG
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F11 TCR in complex with Human Leukocyte Antigen class II allotype DR1 presenting P11T->R modified influenza A virus haemagglutinin (HA)306-318 PKYVKQNTLKLAR
分子名称: 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, HLA class II histocompatibility antigen, ...
著者MacLachlan, B.J, Wall, A, Greenshields-Watson, A.L, Cole, D.K, Rizkallah, P.J, Godkin, A.J.
登録日2023-06-23
公開日2024-06-19
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4 + T cell activation.
Cell Rep, 43, 2024
4WQ2
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Human calpain PEF(S) with (Z)-3-(6-bromondol-3-yl)-2-mercaptoacrylic acid bound
分子名称: (2Z)-3-(6-bromo-1H-indol-3-yl)-2-sulfanylprop-2-enoic acid, 1,2-ETHANEDIOL, CALCIUM ION, ...
著者Adams, S.E, Rizkallah, P.J, Miller, D.J, Hallett, M.B, Allemann, R.K.
登録日2014-10-21
公開日2015-09-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Conformationally restricted calpain inhibitors.
Chem Sci, 6, 2015
4WQ3
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Human calpain PEF(S) with (2Z,2Z')-2,2'-disulfanediylbis(3-(6-bromoindol-3-yl)acrylic acid) bound
分子名称: (2Z)-3-(6-bromo-1H-indol-3-yl)-2-sulfanylprop-2-enoic acid, CALCIUM ION, Calpain small subunit 1
著者Adams, S.E, Robinson, E.J, Rizkallah, P.J, Miller, D.J, Hallett, M.B, Allemann, R.K.
登録日2014-10-21
公開日2015-09-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Conformationally restricted calpain inhibitors.
Chem Sci, 6, 2015
7QA1
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The structure of natural crystals of the Lysinibacillus sphaericus Tpp49Aa1 pesticidal protein elucidated using serial femtosecond crystallography at an X-ray free electron laser
分子名称: Toxin-10 pesticidal protein (Tpp) 49Aa1
著者Williamson, L.J, Rizkallah, P.J, Berry, C, Oberthur, D, Galchenkova, M, Yefanov, O, Bean, R, Best, H.L.
登録日2021-11-15
公開日2023-05-17
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the Lysinibacillus sphaericus Tpp49Aa1 pesticidal protein elucidated from natural crystals using MHz-SFX.
Proc.Natl.Acad.Sci.USA, 120, 2023
6QU8
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Adenovirus Serotype 26 (Ad26) in complex with sialic acid, pH8.0
分子名称: 1,2-ETHANEDIOL, Fiber, N-acetyl-alpha-neuraminic acid, ...
著者Baker, A.T, Rizkallah, P.J, Parker, A.L, Mundy, R.M.
登録日2019-02-26
公開日2019-09-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Human adenovirus type 26 uses sialic acid-bearing glycans as a primary cell entry receptor.
Sci Adv, 5, 2019
6QU6
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Adenovirus Serotype 26 (Ad26) in complex with sialic acid, pH4.0
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Fiber, ...
著者Baker, A.T, Mundy, R.M, Parker, A.L, Rizkallah, P.J.
登録日2019-02-26
公開日2019-09-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.03 Å)
主引用文献Human adenovirus type 26 uses sialic acid-bearing glycans as a primary cell entry receptor.
Sci Adv, 5, 2019
2P5W
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Crystal structures of high affinity human T-cell receptors bound to pMHC reveal native diagonal binding geometry
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, CALCIUM ION, ...
著者Sami, M, Rizkallah, P.J, Dunn, S, Li, Y, Moysey, R, Vuidepot, A, Baston, E, Todorov, P, Molloy, P, Gao, F, Boulter, J.M, Jakobsen, B.K.
登録日2007-03-16
公開日2007-09-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry
Protein Eng.Des.Sel., 20, 2007
2PYF
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Crystal Structures of High Affinity Human T-Cell Receptors Bound to pMHC RevealNative Diagonal Binding Geometry Unbound TCR Clone 5-1
分子名称: SULFATE ION, T-Cell Receptor, Alpha Chain, ...
著者Sami, M, Rizkallah, P.J, Dunn, S, Li, Y, Moysey, R, Vuidepot, A, Baston, E, Todorov, P, Molloy, P, Gao, F, Boulter, J.M, Jakobsen, B.K.
登録日2007-05-16
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry
Protein Eng.Des.Sel., 20, 2007
6STU
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Adenovirus 30 Fiber Knob protein
分子名称: 1,2-ETHANEDIOL, Fiber, GLUTAMIC ACID
著者Baker, A.T, Mundy, R.M, Rizkallah, P.J, Parker, A.L.
登録日2019-09-11
公開日2020-09-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Broad sialic acid usage amongst species D human adenovirus
npj Viruses, 1, 2023
2PYE
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Crystal Structures of High Affinity Human T-Cell Receptors Bound to pMHC RevealNative Diagonal Binding Geometry TCR Clone C5C1 Complexed with MHC
分子名称: 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, Beta-2-microglobulin, Cancer/testis antigen 1B, ...
著者Sami, M, Rizkallah, P.J, Dunn, S, Li, Y, Moysey, R, Vuidepot, A, Baston, E, Todorov, P, Molloy, P, Gao, F, Boulter, J.M, Jakobsen, B.K.
登録日2007-05-16
公開日2007-09-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry
Protein Eng.Des.Sel., 20, 2007
2P5E
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Crystal Structures of High Affinity Human T-Cell Receptors Bound to pMHC Reveal Native Diagonal Binding Geometry
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, Cancer/testis antigen 1B, ...
著者Sami, M, Rizkallah, P.J, Dunn, S, Li, Y, Moysey, R, Vuidepot, A, Baston, E, Todorov, P, Molloy, P, Gao, F, Boulter, J.M, Jakobsen, B.K.
登録日2007-03-15
公開日2007-09-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry
Protein Eng.Des.Sel., 20, 2007
1H91
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The crystal structure of lobster apocrustacyanin A1 using softer X-rays.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CRUSTACYANIN A1 SUBUNIT
著者Cianci, M, Rizkallah, P.J, Olczak, A, Raftery, J, Chayen, N.E, Zagalsky, P.F, Helliwell, J.R.
登録日2001-02-21
公開日2001-09-06
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure of Lobster Apocrustacyanin A1 Using Softer X-Rays
Acta Crystallogr.,Sect.D, 57, 2001
3HG1
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Germline-governed recognition of a cancer epitope by an immunodominant human T cell receptor
分子名称: Beta-2-microglobulin, CANCER/MART-1, GLYCEROL, ...
著者Cole, D.K, Yuan, F, Rizkallah, P.J, Miles, J.J, Gostick, E, Price, D.A, Gao, G.F, Jakobsen, B.K, Sewell, A.K.
登録日2009-05-13
公開日2009-07-28
最終更新日2014-04-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Germ line-governed recognition of a cancer epitope by an immunodominant human T-cell receptor.
J.Biol.Chem., 284, 2009
2BNU
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Structural and kinetic basis for heightened immunogenicity of T cell vaccines
分子名称: T-CELL RECEPTOR ALPHA CHAIN C REGION, T-CELL RECEPTOR BETA CHAIN C REGION
著者Chen, J.-L, Stewart-Jones, G, Bossi, G, Lissin, N.M, Wooldridge, L, Choi, E.M.L, Held, G, Dunbar, P.R, Esnouf, R.M, Sami, M, Boultier, J.M, Rizkallah, P.J, Renner, C, Sewell, A, Van Der Merwe, P.A, Jackobsen, B.K, Griffiths, G, Jones, E.Y, Cerundolo, V.
登録日2005-04-04
公開日2005-05-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines.
J.Exp.Med., 201, 2005
2BNR
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Structural and kinetic basis for heightened immunogenicity of T cell vaccines
分子名称: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, SYNTHETIC PEPTIDE, ...
著者Chen, J.-L, Stewart-Jones, G, Bossi, G, Lissin, N.M, Wooldridge, L, Choi, E.M.L, Held, G, Dunbar, P.R, Esnouf, R.M, Sami, M, Boultier, J.M, Rizkallah, P.J, Renner, C, Sewell, A, van der Merwe, P.A, Jackobsen, B.K, Griffiths, G, Jones, E.Y, Cerundolo, V.
登録日2005-03-31
公開日2005-05-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines
J.Exp.Med., 201, 2005
2BNQ
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Structural and kinetic basis for heightened immunogenicity of T cell vaccines
分子名称: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, SYNTHETIC PEPTIDE, ...
著者Chen, J.-L, Stewart-Jones, G, Bossi, G, Lissin, N.M, Wooldridge, L, Choi, E.M.L, Held, G, Dunbar, P.R, Esnouf, R.M, Sami, M, Boultier, J.M, Rizkallah, P.J, Renner, C, Sewell, A, van der Merwe, P.A, Jackobsen, B.K, Griffiths, G, Jones, E.Y, Cerundolo, V.
登録日2005-03-31
公開日2005-05-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines
J.Exp.Med., 201, 2005
3S4G
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Low Resolution Structure of STNV complexed with RNA
分子名称: Capsid protein, RNA (5'-R(P*AP*AP*A)-3'), RNA (5'-R(P*UP*UP*UP*U)-3')
著者Lane, S.W, Dennis, C.A, Lane, C.L, Trinh, C.H, Rizkallah, P.J, Stockley, P.G, Phillips, S.E.V.
登録日2011-05-19
公開日2011-08-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (6 Å)
主引用文献Construction and crystal structure of recombinant STNV capsids.
J.Mol.Biol., 413, 2011
6QPM
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Adenovirus serotype 10 Fiber-Knob
分子名称: Fiber protein
著者Baker, A.T, Rizkallah, P.J.
登録日2019-02-14
公開日2020-08-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.39 Å)
主引用文献Development of a low-seroprevalence, alpha v beta 6 integrin-selective virotherapy based on human adenovirus type 10.
Mol Ther Oncolytics, 25, 2022
6QZD
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HLA-DR1 with SGP Influenza Matrix Peptide
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Greenshields-Watson, A, Rizkallah, P.J.
登録日2019-03-11
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献CD4+T Cells Recognize Conserved Influenza A Epitopes through Shared Patterns of V-Gene Usage and Complementary Biochemical Features.
Cell Rep, 32, 2020
6QPN
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Adenovirus species D serotype 49 Fiber-Knob
分子名称: Fiber, SULFATE ION
著者Baker, A.T, Rizkallah, P.J.
登録日2019-02-14
公開日2020-08-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献The Fiber Knob Protein of Human Adenovirus Type 49 Mediates Highly Efficient and Promiscuous Infection of Cancer Cell Lines Using a Novel Cell Entry Mechanism
Journal of Virology, 95, 2021
6QZA
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HLA-DR1 with GMF Influenza PB1 Peptide
分子名称: HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ...
著者Greenshields-Watson, A, Rizkallah, P.J.
登録日2019-03-11
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献CD4+T Cells Recognize Conserved Influenza A Epitopes through Shared Patterns of V-Gene Usage and Complementary Biochemical Features.
Cell Rep, 32, 2020
6QPO
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Adenovirus species D serotype 49 Fiber-Knob KO1 mutant
分子名称: Fiber, SULFATE ION
著者Baker, A.T, Rizkallah, P.J.
登録日2019-02-14
公開日2020-08-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The Fiber Knob Protein of Human Adenovirus Type 49 Mediates Highly Efficient and Promiscuous Infection of Cancer Cell Lines Using a Novel Cell Entry Mechanism.
J.Virol., 95, 2021
6QZC
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HLA-DR1 with the QAR Peptide
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Greenshields-Watson, A, Rizkallah, P.J.
登録日2019-03-11
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献CD4+T Cells Recognize Conserved Influenza A Epitopes through Shared Patterns of V-Gene Usage and Complementary Biochemical Features.
Cell Rep, 32, 2020
1DLP
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STRUCTURAL CHARACTERIZATION OF THE NATIVE FETUIN-BINDING PROTEIN SCILLA CAMPANULATA AGGLUTININ (SCAFET): A NOVEL TWO-DOMAIN LECTIN
分子名称: LECTIN SCAFET PRECURSOR
著者Wright, L.M, Reynolds, C.D, Rizkallah, P.J, Allen, A.K, VanDamme, E.J.M, Donovan, M.J, Peumans, W.J.
登録日1999-12-11
公開日2000-02-10
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural characterisation of the native fetuin-binding protein Scilla campanulata agglutinin: a novel two-domain lectin.
FEBS Lett., 468, 2000
1FCV
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CRYSTAL STRUCTURE OF BEE VENOM HYALURONIDASE IN COMPLEX WITH HYALURONIC ACID TETRAMER
分子名称: HYALURONOGLUCOSAMINIDASE, alpha-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranuronic acid
著者Markovic-Housley, Z, Miglierini, G, Soldatova, L, Rizkallah, P.J, Mueller, U, Schirmer, T.
登録日2000-07-19
公開日2001-10-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal structure of hyaluronidase, a major allergen of bee venom.
Structure Fold.Des., 8, 2000

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