2PYF
Crystal Structures of High Affinity Human T-Cell Receptors Bound to pMHC RevealNative Diagonal Binding Geometry Unbound TCR Clone 5-1
Summary for 2PYF
Entry DOI | 10.2210/pdb2pyf/pdb |
Related | 2BNR 2F53 2F54 2P5E 2P5W 2PYE |
Descriptor | T-Cell Receptor, Alpha Chain, T-Cell Receptor, Beta Chain, SULFATE ION, ... (6 entities in total) |
Functional Keywords | t-cell receptor, cdr3, phage display, mutant, high affinity, ny-eso-1, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 50829.16 |
Authors | Sami, M.,Rizkallah, P.J.,Dunn, S.,Li, Y.,Moysey, R.,Vuidepot, A.,Baston, E.,Todorov, P.,Molloy, P.,Gao, F.,Boulter, J.M.,Jakobsen, B.K. (deposition date: 2007-05-16, release date: 2007-09-25, Last modification date: 2023-08-30) |
Primary citation | Sami, M.,Rizkallah, P.J.,Dunn, S.,Molloy, P.,Moysey, R.,Vuidepot, A.,Baston, E.,Todorov, P.,Yi, L.,Gao, F.,Boulter, J.M.,Jakobsen, B.K. Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry Protein Eng.Des.Sel., 20:397-403, 2007 Cited by PubMed: 17644531DOI: 10.1093/protein/gzm033 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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