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PDB: 94 件

5OCX
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Crystal structure of ACPA E4 in complex with CII-C-13-CIT
分子名称: 1,2-ETHANEDIOL, CII-C-13-CIT, Fab fragment anti-citrullinated protein antibody E4 - light chain, ...
著者Dobritzsch, D, Ge, C, Holmdahl, R.
登録日2017-07-04
公開日2018-07-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies.
Arthritis Rheumatol, 71, 2019
5OD3
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BU of 5od3 by Molmil
Crystal structure of R. ruber ADH-A, mutant Y54G, L119Y
分子名称: Alcohol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION
著者Dobritzsch, D, Maurer, D, Hamnevik, E, Enugala, T.R, Widersten, M.
登録日2017-07-04
公開日2018-07-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Stereo- and Regioselectivity in Catalyzed Transformation of a 1,2-Disubstituted Vicinal Diol and the Corresponding Diketone by Wild Type and Laboratory Evolved Alcohol Dehydrogenases
Acs Catalysis, 8, 2018
1GT8
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BU of 1gt8 by Molmil
DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG, TERNARY COMPLEX WITH NADPH AND URACIL-4-ACETIC ACID
分子名称: DIHYDROPYRIMIDINE DEHYDROGENASE, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Dobritzsch, D, Ricagno, S, Schneider, G, Schnackerz, K.D, Lindqvist, Y.
登録日2002-01-14
公開日2002-04-11
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structure of the productive ternary complex of dihydropyrimidine dehydrogenase with NADPH and 5-iodouracil. Implications for mechanism of inhibition and electron transfer.
J. Biol. Chem., 277, 2002
1GTH
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BU of 1gth by Molmil
DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG, TERNARY COMPLEX WITH NADPH AND 5-IODOURACIL
分子名称: (5S)-5-IODODIHYDRO-2,4(1H,3H)-PYRIMIDINEDIONE, 5-IODOURACIL, DIHYDROPYRIMIDINE DEHYDROGENASE, ...
著者Dobritzsch, D, Ricagno, S, Schneider, G, Schnackerz, K.D, Lindqvist, Y.
登録日2002-01-15
公開日2002-04-11
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of the productive ternary complex of dihydropyrimidine dehydrogenase with NADPH and 5-iodouracil. Implications for mechanism of inhibition and electron transfer.
J. Biol. Chem., 277, 2002
1GTE
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BU of 1gte by Molmil
DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG, BINARY COMPLEX WITH 5-IODOURACIL
分子名称: 5-IODOURACIL, DIHYDROPYRIMIDINE DEHYDROGENASE, FLAVIN MONONUCLEOTIDE, ...
著者Dobritzsch, D, Ricagno, S, Schneider, G, Schnackerz, K.D, Lindqvist, Y.
登録日2002-01-15
公開日2002-04-11
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of the productive ternary complex of dihydropyrimidine dehydrogenase with NADPH and 5-iodouracil. Implications for mechanism of inhibition and electron transfer.
J. Biol. Chem., 277, 2002
7QXF
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BU of 7qxf by Molmil
Fructose-6-phosphate aldolase (FSA) mutant R134V, S166G, with covalently bound active site ligand
分子名称: Fructose-6-phosphate aldolase 1
著者Dobritzsch, D, Widersten, M, Engel, S.
登録日2022-01-26
公開日2023-02-08
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Engineered aldolases catalyzing stereoselective aldol reactions between aryl-substituted ketones and aldehydes
Catalysis Science And Technology, 13, 2023
5AHK
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BU of 5ahk by Molmil
Crystal structure of acetohydroxy acid synthase Pf5 from Pseudomonas protegens
分子名称: ACETOLACTATE SYNTHASE II, LARGE SUBUNIT, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Dobritzsch, D, Loschonsky, S, Mueller, M, Schneider, G.
登録日2015-02-06
公開日2016-03-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The Crystal Structure of the Acetohydroxy Acid Synthase Pf5 from Pseudomonas Protegens
To be Published
6FTQ
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BU of 6ftq by Molmil
Crystal structure of human beta-ureidopropionase (beta-alanine synthase) - mutant T299C
分子名称: Beta-ureidopropionase
著者Dobritzsch, D, Maurer, D.
登録日2018-02-23
公開日2018-11-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Crystal structure and pH-dependent allosteric regulation of human beta-ureidopropionase, an enzyme involved in anticancer drug metabolism.
Biochem. J., 475, 2018
2Y5T
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BU of 2y5t by Molmil
Crystal structure of the pathogenic autoantibody CIIC1 in complex with the triple-helical C1 peptide
分子名称: C1, CHLORIDE ION, CIIC1 FAB FRAGMENT HEAVY CHAIN, ...
著者Dobritzsch, D, Lindh, I, Schneider, N, Uysal, H, Nandakumar, K.S, Burkhardt, H, Schneider, G, Holmdahl, R.
登録日2011-01-17
公開日2011-12-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of an Arthritogenic Anticollagen Immune Complex.
Arthritis Rheum., 63, 2011
6FFZ
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BU of 6ffz by Molmil
Crystal structure of R. ruber ADH-A, mutant F43H, Y54L
分子名称: Alcohol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION
著者Dobritzsch, D, Maurer, D, Hamnevik, E, Enugala, T.R, Widersten, M.
登録日2018-01-09
公開日2018-02-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Directed Evolution of Alcohol Dehydrogenase for Improved Stereoselective Redox Transformations of 1-Phenylethane-1,2-diol and Its Corresponding Acyloin.
Biochemistry, 57, 2018
6FFX
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BU of 6ffx by Molmil
Crystal structure of R. ruber ADH-A, mutant F43H
分子名称: Alcohol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION
著者Dobritzsch, D, Maurer, D, Hamnevik, E, Enugala, T.R, Widersten, M.
登録日2018-01-09
公開日2018-02-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Directed Evolution of Alcohol Dehydrogenase for Improved Stereoselective Redox Transformations of 1-Phenylethane-1,2-diol and Its Corresponding Acyloin.
Biochemistry, 57, 2018
6FG0
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BU of 6fg0 by Molmil
Crystal structure of R. ruber ADH-A, mutant Y54G, F43T, L119Y, F282W
分子名称: Alcohol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION
著者Dobritzsch, D, Maurer, D, Hamnevik, E, Enugala, T.R, Widersten, M.
登録日2018-01-09
公開日2018-12-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Stereo- and Regioselectivity in Catalyzed Transformation of a 1,2-Disubstituted Vicinal Diol and the Corresponding Diketone by Wild Type and Laboratory Evolved Alcohol Dehydrogenases
Acs Catalysis, 8, 2018
6SF6
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BU of 6sf6 by Molmil
Crystal structure of the mAb 15A in complex with COMP-epitope P6
分子名称: COMP-reactive monoclonal antibody 15A Fab fragment, heavy chain, light chain, ...
著者Dobritzsch, D, Ge, C, Holmdahl, R.
登録日2019-08-01
公開日2020-06-24
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Antibodies to cartilage oligomeric matrix protein in vivo are pathogenic and clinically relevant in rheumatoid arthritis
To Be Published
5OD8
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BU of 5od8 by Molmil
Crystal structure of the RA-associated mAb B2 (Fab fragment)
分子名称: B2 Fab fragment - Light chain, B2 Fab fragment - heavy chain
著者Dobritzsch, D, Ge, C, Holmdahl, R, Amara, K, Malmstrom, V.
登録日2017-07-05
公開日2018-07-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies.
Arthritis Rheumatol, 71, 2019
5OD0
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BU of 5od0 by Molmil
Crystal structure of ACPA E4
分子名称: Fab fragment of ACPA E4 - Light chain, Fab fragment of ACPA E4 - heavy chain, GLYCEROL
著者Dobritzsch, D, Ge, C, Holmdahl, R.
登録日2017-07-04
公開日2018-07-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies.
Arthritis Rheumatol, 71, 2019
5OCY
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BU of 5ocy by Molmil
Crystal structure of ACPA E4 in complex with CII-C-48-CIT
分子名称: ACPA E4 Fab fragment - heavy chain, ACPA E4 Fab fragment - light chain, CII-C-48-CIT
著者Dobritzsch, D, Ge, C, Holmdahl, R.
登録日2017-07-04
公開日2018-07-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies.
Arthritis Rheumatol, 71, 2019
5OCK
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BU of 5ock by Molmil
Crystal structure of ACPA E4 in complex with CEP1
分子名称: CEP1 peptide (from enolase), Human ACPA E4 Fab fragment - Heavy chain, Human ACPA E4 Fab fragment - Light chain
著者Dobritzsch, D, Ge, C, Holmdahl, R.
登録日2017-07-03
公開日2018-07-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies.
Arthritis Rheumatol, 71, 2019
5ODB
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BU of 5odb by Molmil
Crystal structure of the RA-associated mAb D10 (chimeric Fab fragment)
分子名称: D10 Fab fragment - heavy chain, D10 Fab fragment - light chain, GLYCEROL, ...
著者Dobritzsch, D, Ge, C, Holmdahl, R, Amara, K, Malmstrom, V.
登録日2017-07-05
公開日2018-07-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies.
Arthritis Rheumatol, 71, 2019
4C60
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BU of 4c60 by Molmil
Crystal structure of A. niger ochratoxinase
分子名称: OCHRATOXINASE
著者Dobritzsch, D, Wang, H, Schneider, G, Yu, S.
登録日2013-09-17
公開日2014-07-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and Functional Characterization of Ochratoxinase, a Novel Mycotoxin Degrading Enzyme.
Biochem.J., 462, 2014
4C5Y
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BU of 4c5y by Molmil
Crystal structure of A. niger ochratoxinase
分子名称: OCHRATOXINASE, ZINC ION
著者Dobritzsch, D, Wang, H, Schneider, G, Yu, S.
登録日2013-09-17
公開日2014-07-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and Functional Characterization of Ochratoxinase, a Novel Mycotoxin Degrading Enzyme.
Biochem.J., 462, 2014
4C5Z
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BU of 4c5z by Molmil
Crystal structure of A. niger ochratoxinase
分子名称: OCHRATOXINASE
著者Dobritzsch, D, Wang, H, Schneider, G, Yu, S.
登録日2013-09-17
公開日2014-07-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and Functional Characterization of Ochratoxinase, a Novel Mycotoxin Degrading Enzyme.
Biochem.J., 462, 2014
4C65
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BU of 4c65 by Molmil
Crystal structure of A. niger ochratoxinase
分子名称: OCHRATOXINASE
著者Dobritzsch, D, Wang, H, Schneider, G, Yu, S.
登録日2013-09-17
公開日2014-07-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and Functional Characterization of Ochratoxinase, a Novel Mycotoxin Degrading Enzyme.
Biochem.J., 462, 2014
5MUB
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BU of 5mub by Molmil
ACC1 Fab fragment in complex with citrullinated C1 epitope of CII (CG05)
分子名称: ACC1 Fab fragment heavy chain, ACC1 Fab fragment light chain, triple-helical peptide containing the citrullinated C1 epitope of collagen type II,Collagen alpha-1(II) chain,triple-helical peptide containing the citrullinated C1 epitope of collagen type II
著者Dobritzsch, D, Holmdahl, R, Ge, C.
登録日2017-01-13
公開日2017-07-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage.
JCI Insight, 2, 2017
5MU2
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BU of 5mu2 by Molmil
ACC1 Fab fragment in complex with CII583-591 (CG10)
分子名称: ACC1 Fab fragment heavy chain, ACC1 Fab fragment light chain, synthetic peptide containing the CII583-591 epitope of collagen type II
著者Dobritzsch, D, Holmdahl, R, Ge, C.
登録日2017-01-12
公開日2017-07-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage.
JCI Insight, 2, 2017
5MU0
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ACC1 Fab fragment in complex with citrullinated C1 epitope of CII (IA03)
分子名称: IA03 peptide containing the citrullinated C1 epitope of collagen type II,Collagen alpha-1(II) chain,IA03 peptide containing the citrullinated C1 epitope of collagen type II, heavy chain of ACC1 antibody Fab fragment, light chain of ACC1 antibody Fab fragment
著者Dobritzsch, D, Holmdahl, R, Ge, C.
登録日2017-01-11
公開日2017-07-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage.
JCI Insight, 2, 2017

 

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