6FTQ
Crystal structure of human beta-ureidopropionase (beta-alanine synthase) - mutant T299C
Summary for 6FTQ
| Entry DOI | 10.2210/pdb6ftq/pdb |
| Descriptor | Beta-ureidopropionase (2 entities in total) |
| Functional Keywords | pyrimidine degradation, n-carbamyl-beta-alanine amidohydrolase, 5-fluorouracil metabolizing enzyme, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 43883.69 |
| Authors | Dobritzsch, D.,Maurer, D. (deposition date: 2018-02-23, release date: 2018-11-21, Last modification date: 2024-01-17) |
| Primary citation | Maurer, D.,Lohkamp, B.,Krumpel, M.,Widersten, M.,Dobritzsch, D. Crystal structure and pH-dependent allosteric regulation of human beta-ureidopropionase, an enzyme involved in anticancer drug metabolism. Biochem. J., 475:2395-2416, 2018 Cited by PubMed: 29976570DOI: 10.1042/BCJ20180222 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.08 Å) |
Structure validation
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