6FTQ

Crystal structure of human beta-ureidopropionase (beta-alanine synthase) - mutant T299C

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001701	biological_process	in utero embryonic development
A	0001889	biological_process	liver development
A	0003837	molecular_function	beta-ureidopropionase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006248	biological_process	CMP catabolic process
A	0006249	biological_process	dCMP catabolic process
A	0008270	molecular_function	zinc ion binding
A	0016787	molecular_function	hydrolase activity
A	0019482	biological_process	beta-alanine metabolic process
A	0019483	biological_process	beta-alanine biosynthetic process
A	0033396	biological_process	beta-alanine biosynthetic process via 3-ureidopropionate
A	0042803	molecular_function	protein homodimerization activity
A	0046050	biological_process	UMP catabolic process
A	0046079	biological_process	dUMP catabolic process
A	0046135	biological_process	pyrimidine nucleoside catabolic process
A	0051260	biological_process	protein homooligomerization
A	0051289	biological_process	protein homotetramerization
A	0070062	cellular_component	extracellular exosome

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00054

Chain	Residue	Details
A	GLU119

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000255|PROSITE-ProRule:PRU00054

Chain	Residue	Details
A	LYS196

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site_id	SWS_FT_FI3
Number of Residues	1
Details	ACT_SITE: Nucleophile => ECO:0000255|PROSITE-ProRule:PRU00054, ECO:0000269|PubMed:29976570

Chain	Residue	Details
A	CSD233

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q03248

Chain	Residue	Details
A	SER378

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