Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 378 件
7WEK
DownloadVisualize
BU of 7wek by Molmil
Crystal structure of the mouse Wdr47 NTD in complex with the WBR motif form Camsap3.
分子名称: WBR motif form Calmodulin-regulated spectrin-associated protein 3, WD repeat-containing protein 47
著者Ren, J.Q, Li, D, Feng, W.
登録日2021-12-23
公開日2022-11-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Intertwined Wdr47-NTD dimer recognizes a basic-helical motif in Camsap proteins for proper central-pair microtubule formation.
Cell Rep, 41, 2022
7WEJ
DownloadVisualize
BU of 7wej by Molmil
Crystal structure of the mouse Wdr47 NTD.
分子名称: WD repeat-containing protein 47
著者Ren, J.Q, Li, D, Feng, W.
登録日2021-12-23
公開日2022-11-30
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Intertwined Wdr47-NTD dimer recognizes a basic-helical motif in Camsap proteins for proper central-pair microtubule formation.
Cell Rep, 41, 2022
4JGZ
DownloadVisualize
BU of 4jgz by Molmil
Crystal structure of human coxsackievirus A16 uncoating intermediate (space group I222)
分子名称: Polyprotein, capsid protein VP1, capsid protein VP2, ...
著者Ren, J, Wang, X, Hu, Z, Gao, Q, Sun, Y, Li, X, Porta, C, Walter, T.S, Gilbert, R.J, Zhao, Y, Axford, D, Williams, M, McAuley, K, Rowlands, D.J, Yin, W, Wang, J, Stuart, D.I, Rao, Z, Fry, E.E.
登録日2013-03-04
公開日2013-06-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Picornavirus uncoating intermediate captured in atomic detail.
Nat Commun, 4, 2013
5GKK
DownloadVisualize
BU of 5gkk by Molmil
Crystal structure of a homing endonuclease, I-TnaI
分子名称: Putative homing endonuclease
著者Ren, J.
登録日2016-07-04
公開日2017-07-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Crystal structure of a homing endonuclease, I-TnaI
To Be Published
4JGY
DownloadVisualize
BU of 4jgy by Molmil
Crystal structure of human coxsackievirus A16 uncoating intermediate (space group P4232)
分子名称: Polyprotein, capsid protein VP1, capsid protein VP2, ...
著者Ren, J, Wang, X, Hu, Z, Gao, Q, Sun, Y, Li, X, Porta, C, Walter, T.S, Gilbert, R.J, Zhao, Y, Axford, D, Williams, M, Mcauley, K, Rowlands, D.J, Yin, W, Wang, J, Stuart, D.I, Rao, Z, Fry, E.E.
登録日2013-03-04
公開日2013-06-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Picornavirus uncoating intermediate captured in atomic detail.
Nat Commun, 4, 2013
7D8V
DownloadVisualize
BU of 7d8v by Molmil
Crystal Structure of A Kinesin-3 KIF13B mutant-T192Y
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, Kinesin family member 13B, ...
著者Ren, J.Q, Feng, W.
登録日2020-10-10
公開日2021-10-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Motor domain-mediated autoinhibition dictates axonal transport by the kinesin UNC-104/KIF1A.
Plos Genet., 17, 2021
4IA0
DownloadVisualize
BU of 4ia0 by Molmil
Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors
分子名称: 5-bromo-2-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-6-octylpyrimidin-4(3H)-one, MAGNESIUM ION, ZINC ION, ...
著者Ren, J, Chen, T, Xu, Y.
登録日2012-12-05
公開日2014-01-01
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Exploration of the 5-bromopyrimidin-4(3H)-ones as potent inhibitors of PDE5.
Bioorg.Med.Chem.Lett., 23, 2013
4I9Z
DownloadVisualize
BU of 4i9z by Molmil
Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors
分子名称: 5-bromo-2-{5-[(4-methylpiperazin-1-yl)acetyl]-2-propoxyphenyl}-6-(propan-2-yl)pyrimidin-4(3H)-one, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ...
著者Ren, J, Chen, T, Xu, Y.
登録日2012-12-05
公開日2014-01-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Exploration of the 5-bromopyrimidin-4(3H)-ones as potent inhibitors of PDE5.
Bioorg.Med.Chem.Lett., 23, 2013
4MJS
DownloadVisualize
BU of 4mjs by Molmil
crystal structure of a PB1 complex
分子名称: 1,2-ETHANEDIOL, Protein kinase C zeta type, Sequestosome-1
著者Ren, J, Wang, Z.X, Wu, J.W.
登録日2013-09-04
公開日2014-08-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and biochemical insights into the homotypic PB1-PB1 complex between PKC zeta and p62
Sci China Life Sci, 57, 2014
7DM4
DownloadVisualize
BU of 7dm4 by Molmil
Solution structure of ARID4B Tudor domain
分子名称: AT-rich interactive domain-containing protein 4B
著者Ren, J, Yao, H, Hu, W, Perrett, S, Feng, Y, Gong, W.
登録日2020-12-02
公開日2021-03-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis for the DNA-binding activity of human ARID4B Tudor domain.
J.Biol.Chem., 296, 2021
7FIA
DownloadVisualize
BU of 7fia by Molmil
Structure of AcrIF23
分子名称: AcrIF23
著者Ren, J, Yue, F.
登録日2021-07-30
公開日2022-07-27
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structural and mechanistic insights into the inhibition of type I-F CRISPR-Cas system by anti-CRISPR protein AcrIF23.
J.Biol.Chem., 298, 2022
8QSQ
DownloadVisualize
BU of 8qsq by Molmil
Locally refined SARS-CoV-2 BA-2.86 Spike receptor binding domain (RBD) complexed with angiotensin converting enzyme 2 (ACE2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike protein S2'
著者Ren, J, Stuart, D.I, Duyvesteyn, H.M.E.
登録日2023-10-11
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献The emerging BA.2.86 Omicron sub-lineage balances antibody escape and ACE2 affinity
To Be Published
8QTD
DownloadVisualize
BU of 8qtd by Molmil
Local refinement of SARS-CoV-2 BA.2.86 Spike and XBB-7 Fab
分子名称: Spike glycoprotein,Fibritin, XBB-7 fab heavy chain, XBB-7 fab light chain
著者Ren, J, Duyvesteyn, H.M.E, Stuart, D.I.
登録日2023-10-12
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献The emerging BA.2.86 Omicron sub-lineage balances antibody escape and ACE2 affinity
To Be Published
1DRY
DownloadVisualize
BU of 1dry by Molmil
CRYSTAL STRUCTURE OF CLAVAMINATE SYNTHASE IN COMPLEX WITH FE(II), 2-OXOGLUTARATE AND N-ALPHA-L-ACETYL ARGININE
分子名称: 2-OXOGLUTARIC ACID, CLAVAMINATE SYNTHASE 1, FE (II) ION, ...
著者Zhang, Z.H, Ren, J, Stammers, D.K, Baldwin, J.E, Harlos, K, Schofield, C.J.
登録日2000-01-06
公開日2000-07-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase.
Nat.Struct.Biol., 7, 2000
1DS1
DownloadVisualize
BU of 1ds1 by Molmil
CRYSTAL STRUCTURE OF CLAVAMINATE SYNTHASE IN COMPLEX WITH FE(II) AND 2-OXOGLUTARATE
分子名称: 2-OXOGLUTARIC ACID, CLAVAMINATE SYNTHASE 1, FE (II) ION, ...
著者Zhang, Z.H, Ren, J, Stammers, D.K, Baldwin, J.E, Harlos, K, Schofield, C.J.
登録日2000-01-06
公開日2000-07-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase.
Nat.Struct.Biol., 7, 2000
1DRT
DownloadVisualize
BU of 1drt by Molmil
CRYSTAL STRUCTURE OF CLAVAMINATE SYNTHASE IN COMPLEX WITH FE(II), 2-OXOGLUTARATE AND PROCLAVAMINIC ACID
分子名称: 2-OXOGLUTARIC ACID, 5-AMINO-3-HYDROXY-2-(2-OXO-AZETIDIN-1-YL)-PENTANOIC ACID, CLAVAMINATE SYNTHASE 1, ...
著者Zhang, Z.H, Ren, J, Stammers, D.K, Baldwin, J.E, Harlos, K, Schofield, C.J.
登録日2000-01-06
公開日2000-07-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase.
Nat.Struct.Biol., 7, 2000
1DS0
DownloadVisualize
BU of 1ds0 by Molmil
CRYSTAL STRUCTURE OF CLAVAMINATE SYNTHASE
分子名称: ACETATE ION, CLAVAMINATE SYNTHASE 1, SULFATE ION
著者Zhang, Z.H, Ren, J, Stammers, D.K, Baldwin, J.E, Harlos, K, Schofield, C.J.
登録日2000-01-06
公開日2000-07-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase.
Nat.Struct.Biol., 7, 2000
1C1B
DownloadVisualize
BU of 1c1b by Molmil
CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GCA-186
分子名称: 6-(3',5'-DIMETHYLBENZYL)-1-ETHOXYMETHYL-5-ISOPROPYLURACIL, HIV-1 REVERSE TRANSCRIPTASE (A-CHAIN), HIV-1 REVERSE TRANSCRIPTASE (B-CHAIN)
著者Hopkins, A.L, Ren, J, Tanaka, H, Baba, B, Okamato, M, Stuart, D.I, Stammers, D.K.
登録日1999-07-21
公開日2000-07-21
最終更新日2014-11-12
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Design of MKC-442 (emivirine) analogues with improved activity against drug-resistant HIV mutants.
J.Med.Chem., 42, 1999
1C1C
DownloadVisualize
BU of 1c1c by Molmil
CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH TNK-6123
分子名称: 6-(cyclohexylsulfanyl)-1-(ethoxymethyl)-5-(1-methylethyl)pyrimidine-2,4(1H,3H)-dione, HIV-1 REVERSE TRANSCRIPTASE (A-CHAIN), HIV-1 REVERSE TRANSCRIPTASE (B-CHAIN)
著者Hopkins, A.L, Ren, J, Tanaka, H, Baba, M, Okamato, M, Stuart, D.I, Stammers, D.K.
登録日1999-07-21
公開日2000-07-21
最終更新日2014-11-12
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Design of MKC-442 (emivirine) analogues with improved activity against drug-resistant HIV mutants.
J.Med.Chem., 42, 1999
1TL3
DownloadVisualize
BU of 1tl3 by Molmil
Crystal structure of hiv-1 reverse transcriptase in complex with gw450557
分子名称: 6-CHLORO-4-(CYCLOHEXYLOXY)-3-ISOPROPYLQUINOLIN-2(1H)-ONE, PHOSPHATE ION, Pol polyprotein, ...
著者Hopkins, A.L, Ren, J, Stuart, D.I, Stammers, D.K.
登録日2004-06-09
公開日2004-12-07
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1.
J.Med.Chem., 47, 2004
1TKT
DownloadVisualize
BU of 1tkt by Molmil
CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GW426318
分子名称: 6-CHLORO-4-(CYCLOHEXYLOXY)-3-PROPYLQUINOLIN-2(1H)-ONE, MAGNESIUM ION, PHOSPHATE ION, ...
著者Hopkins, A.L, Ren, J, Stuart, D.I, Stammers, D.K.
登録日2004-06-09
公開日2004-12-07
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1.
J.Med.Chem., 47, 2004
1TL1
DownloadVisualize
BU of 1tl1 by Molmil
CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GW451211
分子名称: 6-CHLORO-4-(CYCLOHEXYLSULFINYL)-3-PROPYLQUINOLIN-2(1H)-ONE, PHOSPHATE ION, Pol polyprotein, ...
著者Hopkins, A.L, Ren, J, Stuart, D.I, Stammers, D.K.
登録日2004-06-09
公開日2004-12-07
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1.
J.Med.Chem., 47, 2004
1TKZ
DownloadVisualize
BU of 1tkz by Molmil
CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GW429576
分子名称: 6-CHLORO-4-(CYCLOHEXYLSULFANYL)-3-PROPYLQUINOLIN-2(1H)-ONE, PHOSPHATE ION, Pol polyprotein, ...
著者Hopkins, A.L, Ren, J, Stuart, D.I, Stammers, D.K.
登録日2004-06-09
公開日2004-12-07
最終更新日2020-01-15
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1.
J.Med.Chem., 47, 2004
4V5V
DownloadVisualize
BU of 4v5v by Molmil
Structure of respiratory syncytial virus nucleocapsid protein, P1 crystal form
分子名称: RESPIRATORY SYNCYTIAL VIRUS NUCLEOCAPSID PROTEIN, RNA
著者El Omari, K, Dhaliwal, B, Ren, J, Abrescia, N.G.A, Lockyer, M, Powell, K.L, Hawkins, A.R, Stammers, D.K.
登録日2011-05-04
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structures of Respiratory Syncytial Virus Nucleocapsid Protein from Two Crystal Forms: Details of Potential Packing Interactions in the Native Helical Form.
Acta Crystallogr.,Sect.F, 67, 2011
7QNY
DownloadVisualize
BU of 7qny by Molmil
The receptor binding domain of SARS-CoV-2 spike glycoprotein in complex with COVOX-58 and COVOX-158 Fabs
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, COVOX-158 heavy chain, COVOX-158 light chain, ...
著者Zhou, D, Ren, J, Stuart, D.I.
登録日2021-12-23
公開日2022-01-19
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses.
Cell, 185, 2022

219869

件を2024-05-15に公開中

PDB statisticsPDBj update infoContact PDBjnumon