1MU2

CRYSTAL STRUCTURE OF HIV-2 REVERSE TRANSCRIPTASE

Summary for 1MU2

Entry DOI	10.2210/pdb1mu2/pdb
Descriptor	HIV-2 RT, SULFATE ION, GLYCEROL, ... (5 entities in total)
Functional Keywords	hiv-2 reverse transcriptase, aids, polymerase, drug design, transferase
Biological source	Human immunodeficiency virus 2 More
Cellular location	Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P04584 P04584
Total number of polymer chains	2
Total formula weight	116925.14
Authors	Ren, J.,Bird, L.E.,Chamberlain, P.P.,Stewart-Jones, G.B.,Stuart, D.I.,Stammers, D.K. (deposition date: 2002-09-23, release date: 2002-10-30, Last modification date: 2023-10-25)
Primary citation	Ren, J.,Bird, L.E.,Chamberlain, P.P.,Stewart-Jones, G.B.,Stuart, D.I.,Stammers, D.K. Structure of HIV-2 reverse transcriptase at 2.35-A resolution and the mechanism of resistance to non-nucleoside inhibitors Proc.Natl.Acad.Sci.USA, 99:14410-14415, 2002 Cited by PubMed: 12386343 DOI: 10.1073/pnas.222366699 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation