Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| A | 0004523 | molecular_function | RNA-DNA hybrid ribonuclease activity |
| A | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
| B | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| B | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1300 |
| Chain | Residue |
| A | ARG165 |
| A | GLU169 |
| A | ARG172 |
| A | LYS173 |
| B | LYS35 |
| B | GLU139 |
| B | LYS142 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1301 |
| Chain | Residue |
| A | LYS223 |
| A | ASP224 |
| A | PHE221 |
| A | GLN222 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1302 |
| Chain | Residue |
| A | HIS162 |
| A | GLN166 |
| B | THR296 |
| B | GLU297 |
| B | LEU298 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1303 |
| Chain | Residue |
| A | HIS538 |
| A | LYS539 |
| A | GLY540 |
| A | GLN545 |
| A | HIS549 |
| B | LYS43 |
| B | GLU44 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1304 |
| Chain | Residue |
| A | ARG125 |
| A | LYS147 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1305 |
| Chain | Residue |
| A | LYS275 |
| A | THR276 |
| A | LYS277 |
| A | HOH1277 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1306 |
| Chain | Residue |
| A | GLU324 |
| A | ARG384 |
| A | ILE385 |
| A | HOH1026 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1307 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1308 |
| Chain | Residue |
| A | LYS539 |
| B | LYS275 |
| B | THR276 |
| B | LYS277 |
| B | HOH1133 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1309 |
| Chain | Residue |
| B | GLY316 |
| B | HIS317 |
| B | TYR318 |
| B | TYR319 |
| B | TRP382 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1310 |
| Chain | Residue |
| A | LYS539 |
| B | ASN265 |
| B | GLN269 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1311 |
| Chain | Residue |
| A | ALA174 |
| A | ASN175 |
| A | GLN204 |
| B | PRO272 |
| B | ILE309 |
| B | GLU313 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1312 |
| Chain | Residue |
| A | HIS278 |
| A | ARG281 |
| A | THR296 |
| A | LEU298 |
| A | HOH1111 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1313 |
| Chain | Residue |
| A | ARG394 |
| A | ASP414 |
| A | PHE415 |
| A | HOH1117 |
| A | HOH1232 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1314 |
| Chain | Residue |
| B | ASN362 |
| B | ARG365 |
| B | TYR404 |
| site_id | BC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1315 |
| Chain | Residue |
| A | ARG460 |
| A | HOH1121 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1316 |
| Chain | Residue |
| A | SER498 |
| A | GLN499 |
| A | TYR500 |
| A | HOH1125 |
| site_id | BC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1317 |
| Chain | Residue |
| B | LYS20 |
| B | LEU21 |
| B | ARG22 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1318 |
| Chain | Residue |
| A | THR296 |
| A | GLU297 |
| B | HIS162 |
| B | GLN166 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1319 |
| Chain | Residue |
| A | LYS249 |
| A | TRP252 |
| A | GLU300 |
| A | ARG307 |
| B | GLN161 |
| B | ARG165 |
| site_id | CC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1320 |
| Chain | Residue |
| B | VAL416 |
| B | SER417 |
| site_id | CC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1321 |
| Chain | Residue |
| A | LYS82 |
| A | SER284 |
| A | GLY285 |
| site_id | CC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 1400 |
| Chain | Residue |
| A | GLY99 |
| A | LEU100 |
| A | ALA101 |
| A | ILE179 |
| A | HOH1176 |
| B | ASN136 |
| B | ALA138 |
| site_id | CC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 1401 |
| Chain | Residue |
| B | ASN81 |
| B | GLY152 |
| B | MET184 |
| B | ILE410 |
| B | ILE75 |
| B | PHE77 |
| site_id | CC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 1402 |
| Chain | Residue |
| B | LEU270 |
| B | TYR271 |
| B | PRO272 |
| B | GLU313 |
| B | TYR318 |
| B | LYS346 |
| B | ILE347 |
| site_id | CC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 1403 |
| Chain | Residue |
| A | LYS376 |
| B | GLN23 |
| B | TRP24 |
| B | PRO25 |
| site_id | CC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 1404 |
| Chain | Residue |
| A | LYS173 |
| A | LYS176 |
| B | GLY273 |
| B | LYS275 |
| B | HOH1055 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Region: {"description":"RT 'primer grip'","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 32 |
| Details | Motif: {"description":"Tryptophan repeat motif","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Site: {"description":"Essential for RT p66/p51 heterodimerization","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Site: {"description":"Cleavage; by viral protease; partial","evidences":[{"evidenceCode":"ECO:0000250"}]} |
