5FXG
 
 | | GLUN1B-GLUN2B NMDA RECEPTOR IN ACTIVE CONFORMATION | | Descriptor: | N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B | | Authors: | Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H. | | Deposit date: | 2016-03-02 | | Release date: | 2016-05-11 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (6.8 Å) | | Cite: | Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil.
Nature, 534, 2016
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5EOH
 | | Crystal structure of murine neuroglobin at 270 MPa pressure | | Descriptor: | Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | | Authors: | Colloc'h, N, Girard, E, Vallone, B, Prange, T. | | Deposit date: | 2015-11-10 | | Release date: | 2016-10-19 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Determinants of neuroglobin plasticity highlighted by joint coarse-grained simulations and high pressure crystallography.
Sci Rep, 7, 2017
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5FXI
 | | GluN1b-GluN2B NMDA receptor structure in non-active-2 conformation | | Descriptor: | N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B | | Authors: | Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H. | | Deposit date: | 2016-03-02 | | Release date: | 2016-05-11 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (6.4 Å) | | Cite: | Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil.
Nature, 534, 2016
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5FST
 | | Structure of lysozyme prepared by the 'soak-and-freeze' method under 100 bar of krypton pressure | | Descriptor: | CHLORIDE ION, KRYPTON, LYSOZYME C, ... | | Authors: | Lafumat, B, Mueller-Dieckmann, C, Colloc'h, N, Prange, T, Royant, A, van der Linden, P, Carpentier, P. | | Deposit date: | 2016-01-07 | | Release date: | 2016-10-26 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Gas-Sensitive Biological Crystals Processed in Pressurized Oxygen and Krypton Atmospheres: Deciphering Gas Channels in Proteins Using a Novel `Soak-and-Freeze' Methodology.
J.Appl.Crystallogr., 49, 2016
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1ID9
 | | STRUCTURE OF THE HYBRID RNA/DNA R-GCUUCGGC-D[F]U IN PRESENCE OF RH(NH3)6+++ | | Descriptor: | 5'-R(*GP*CP*UP*UP*CP*GP*GP*C)-D(P*(UFP))-3', CHLORIDE ION, RHODIUM HEXAMINE ION | | Authors: | Cruse, W, Saludjian, P, Neuman, A, Prange, T. | | Deposit date: | 2001-04-04 | | Release date: | 2001-04-12 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Destabilizing effect of a fluorouracil extra base in a hybrid RNA duplex compared with bromo and chloro analogues.
Acta Crystallogr.,Sect.D, 57, 2001
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5EQM
 | | Crystal structure of murine neuroglobin at 310 MPa pressure | | Descriptor: | Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | | Authors: | Colloc'h, N, Girard, E, Vallone, B, Prange, T. | | Deposit date: | 2015-11-13 | | Release date: | 2016-10-19 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Determinants of neuroglobin plasticity highlighted by joint coarse-grained simulations and high pressure crystallography.
Sci Rep, 7, 2017
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2ZDL
 | | Exploring trypsin S3 pocket | | Descriptor: | (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentyloxy)ethanoyl)pyrrolidine-2-carboxamide, CALCIUM ION, Cationic trypsin, ... | | Authors: | Baum, B, Brandt, T, Heine, A, Klebe, G. | | Deposit date: | 2007-11-26 | | Release date: | 2008-10-14 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties
J.Mol.Biol., 405, 2011
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2ZKA
 | | Urate oxidase complexed with 8-azaxanthine under 1.0 MPa oxygen pressure | | Descriptor: | 8-AZAXANTHINE, OXYGEN MOLECULE, SODIUM ION, ... | | Authors: | Colloc'h, N, Gabison, L, Chiadmi, M, Abraini, J.H, Prange, T. | | Deposit date: | 2008-03-13 | | Release date: | 2008-10-07 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.61 Å) | | Cite: | Oxygen pressurized X-ray crystallography: probing the dioxygen binding site in cofactorless urate oxidase and implications for its catalytic mechanism.
Biophys.J., 95, 2008
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3BK8
 | | Urate oxidase aza-xanthine complex in cyanide | | Descriptor: | 8-AZAXANTHINE, SODIUM ION, Uricase | | Authors: | Gabison, L, Prange, T, Colloc'h, N, El Hajji, M, Castro, B, Chiadmi, M. | | Deposit date: | 2007-12-06 | | Release date: | 2008-08-12 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural analysis of urate oxidase in complex with its natural substrate inhibited by cyanide: Mechanistic implications
Bmc Struct.Biol., 8, 2008
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2IBA
 | | Urate oxidase from Aspergillus flavus complexed with its inhibitor 8-azaxanthine | | Descriptor: | 8-AZAXANTHINE, SODIUM ION, Uricase | | Authors: | Colloc'h, N, Retailleau, P, Sopkova-de Oliveira Santos, J, Prange, T. | | Deposit date: | 2006-09-11 | | Release date: | 2007-02-06 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Protein Crystallography under Xenon and Nitrous Oxide Pressure: Comparison with In Vivo Pharmacology Studies and Implications for the Mechanism of Inhaled Anesthetic Action
Biophys.J., 92, 2007
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1ISH
 | | Crystal Structure Analysis of BST-1/CD157 complexed with ethenoNADP | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ETHENO-NADP, bone marrow stromal cell antigen 1 | | Authors: | Yamamoto-Katayama, S, Ariyoshi, M, Ishihara, K, Hirano, T, Jingami, H, Morikawa, K. | | Deposit date: | 2001-12-05 | | Release date: | 2002-03-13 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystallographic studies on human BST-1/CD157 with ADP-ribosyl cyclase and NAD glycohydrolase activities.
J.Mol.Biol., 316, 2002
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3PKT
 | | Urate oxidase under 2 MPa / 20 bars pressure of nitrous oxide | | Descriptor: | 8-AZAXANTHINE, NITROUS OXIDE, SODIUM ION, ... | | Authors: | Marassio, G, Colloc'h, N, Prange, T, Abraini, J.H. | | Deposit date: | 2010-11-12 | | Release date: | 2011-04-06 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Pressure-response analysis of anesthetic gases xenon and nitrous oxide on urate oxidase: a crystallographic study.
Faseb J., 25, 2011
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3BXX
 | | Binding of two substrate analogue molecules to dihydroflavonol 4-reductase alters the functional geometry of the catalytic site | | Descriptor: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, dihydroflavonol 4-reductase | | Authors: | Trabelsi, N, Petit, P, Granier, T, Langlois d'Estaintot, B, Delrot, S, Gallois, B. | | Deposit date: | 2008-01-15 | | Release date: | 2008-10-21 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural evidence for the inhibition of grape dihydroflavonol 4-reductase by flavonols
Acta Crystallogr.,Sect.D, D64, 2008
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3PKS
 | | Urate oxidase under 1.5 MPa / 15 bars pressure of nitrous oxide | | Descriptor: | 8-AZAXANTHINE, NITROUS OXIDE, SODIUM ION, ... | | Authors: | Marassio, G, Colloc'h, N, Prange, T, Abraini, J.H. | | Deposit date: | 2010-11-12 | | Release date: | 2011-04-06 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Pressure-response analysis of anesthetic gases xenon and nitrous oxide on urate oxidase: a crystallographic study.
Faseb J., 25, 2011
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3PLI
 | | Urate oxidase under 1.8 MPa / 18 bars pressure of equimolar mixture xenon : nitrous oxide | | Descriptor: | 8-AZAXANTHINE, NITROUS OXIDE, SODIUM ION, ... | | Authors: | Marassio, G, Colloc'h, N, Prange, T, Abraini, J.H. | | Deposit date: | 2010-11-15 | | Release date: | 2011-04-06 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Pressure-response analysis of anesthetic gases xenon and nitrous oxide on urate oxidase: a crystallographic study.
Faseb J., 25, 2011
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3PK3
 | | urate oxidase under 3.0 MPa / 30 bars pressure of nitrous oxide | | Descriptor: | 8-AZAXANTHINE, NITROUS OXIDE, SODIUM ION, ... | | Authors: | Marassio, G, Colloc'h, N, Prange, T, Abraini, J.H. | | Deposit date: | 2010-11-11 | | Release date: | 2011-04-06 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Pressure-response analysis of anesthetic gases xenon and nitrous oxide on urate oxidase: a crystallographic study.
Faseb J., 25, 2011
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3PKF
 | | Urate oxidase under 0.2 MPa / 2 bars pressure of equimolar mixture of xenon and nitrous oxide | | Descriptor: | 8-AZAXANTHINE, SODIUM ION, Uricase, ... | | Authors: | Marassio, G, Colloc'h, N, Prange, T, Abraini, J.H. | | Deposit date: | 2010-11-11 | | Release date: | 2011-04-06 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Pressure-response analysis of anesthetic gases xenon and nitrous oxide on urate oxidase: a crystallographic study.
Faseb J., 25, 2011
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3PLH
 | | urate oxidase under 1.5 MPa / 15 bars pressure of equimolar mixture xenon : nitrous oxide | | Descriptor: | 8-AZAXANTHINE, NITROUS OXIDE, SODIUM ION, ... | | Authors: | Marassio, G, Colloc'h, N, Prange, T, Abraini, J.H. | | Deposit date: | 2010-11-15 | | Release date: | 2011-04-06 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Pressure-response analysis of anesthetic gases xenon and nitrous oxide on urate oxidase: a crystallographic study.
Faseb J., 25, 2011
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4AJW
 | | Discovery and Optimization of New Benzimidazole- and Benzoxazole-Pyrimidone Selective PI3KBeta Inhibitors for the Treatment of Phosphatase and TENsin homologue (PTEN)-Deficient Cancers | | Descriptor: | 2-[(1-methyl-1H-benzimidazol-2-yl)methyl]-6-morpholin-4-ylpyrimidin-4(3H)-one, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM | | Authors: | Certal, V, Halley, F, Virone-Oddos, A, Delorme, C, Karlsson, A, Rak, A, Thompson, F, Filoche-Romme, B, El-Ahmad, Y, Carry, J.C, Abecassis, P.Y, Lejeune, P, Bonnevaux, H, Nicolas, J.P, Bertrand, T, Marquette, J.P, Michot, N, Benard, T, Below, P, Vade, I, Chatreaux, F, Lebourg, G, Pilorge, F, Angouillant-Boniface, O, Louboutin, A, Lengauer, C, Schio, L. | | Deposit date: | 2012-02-20 | | Release date: | 2012-05-16 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Discovery and Optimization of New Benzimidazole- and Benzoxazole-Pyrimidone Selective Pi3Kbeta Inhibitors for the Treatment of Phosphatase and Tensin Homologue (Pten)-Deficient Cancers.
J.Med.Chem., 55, 2012
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5EV5
 | | Crystal structure of murine neuroglobin mutant V101F at 150 MPa pressure | | Descriptor: | Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | | Authors: | Colloc'h, N, Girard, E, Vallone, B, Prange, T. | | Deposit date: | 2015-11-19 | | Release date: | 2016-10-19 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Determinants of neuroglobin plasticity highlighted by joint coarse-grained simulations and high pressure crystallography.
Sci Rep, 7, 2017
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3C1T
 | | Binding of two substrate analogue molecules to dihydroflavonol 4-reductase alters the functional geometry of the catalytic site | | Descriptor: | 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, dihydroflavonol 4-reductase | | Authors: | Trabelsi, N, Petit, P, Granier, T, Langlois d'Estaintot, B, Delrot, S, Gallois, B. | | Deposit date: | 2008-01-24 | | Release date: | 2008-02-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.252 Å) | | Cite: | Structural evidence for the inhibition of grape dihydroflavonol 4-reductase by flavonols
Acta Crystallogr.,Sect.D, D64, 2008
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2ZKB
 | | Urate oxidase complexed with 8-azaxanthine under 2.5 MPa oxygen pressure | | Descriptor: | 8-AZAXANTHINE, OXYGEN MOLECULE, SODIUM ION, ... | | Authors: | Colloc'h, N, Gabison, L, Chiadmi, M, Abraini, J.H, Prange, T. | | Deposit date: | 2008-03-14 | | Release date: | 2008-10-07 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.61 Å) | | Cite: | Oxygen pressurized X-ray crystallography: probing the dioxygen binding site in cofactorless urate oxidase and implications for its catalytic mechanism.
Biophys.J., 95, 2008
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6CNA
 | | GluN1-GluN2B NMDA receptors with exon 5 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | | Authors: | Furukawa, H, Grant, T, Grigorieff, N. | | Deposit date: | 2018-03-07 | | Release date: | 2018-10-03 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Structural Mechanism of Functional Modulation by Gene Splicing in NMDA Receptors.
Neuron, 98, 2018
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2ZDN
 | | Exploring trypsin S3 pocket | | Descriptor: | (S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclopentylpropanoyl)pyrrolidine-2-carboxamide, CALCIUM ION, Cationic trypsin, ... | | Authors: | Baum, B, Brandt, T, Heine, A, Klebe, G. | | Deposit date: | 2007-11-26 | | Release date: | 2008-10-14 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties
J.Mol.Biol., 405, 2011
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1LCN
 | | Monoclinic hen egg white lysozyme, thiocyanate complex | | Descriptor: | PROTEIN (LYSOZYME), THIOCYANATE ION | | Authors: | Hamiaux, C, Prange, T, Ducruix, A, Vaney, M.C. | | Deposit date: | 1998-10-27 | | Release date: | 1998-11-04 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Structural effects of monovalent anions on polymorphic lysozyme crystals.
Acta Crystallogr.,Sect.D, 57, 2001
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