3C1T
Binding of two substrate analogue molecules to dihydroflavonol 4-reductase alters the functional geometry of the catalytic site
Summary for 3C1T
Entry DOI | 10.2210/pdb3c1t/pdb |
Related | 2IOD 3BXX |
Descriptor | dihydroflavonol 4-reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, ... (4 entities in total) |
Functional Keywords | short chain dehydrogenase reductase, rossmann fold, flavonoids, oxidoreductase |
Biological source | Vitis vinifera (wine grape) |
Total number of polymer chains | 4 |
Total formula weight | 156296.88 |
Authors | Trabelsi, N.,Petit, P.,Granier, T.,Langlois d'Estaintot, B.,Delrot, S.,Gallois, B. (deposition date: 2008-01-24, release date: 2008-02-19, Last modification date: 2023-08-30) |
Primary citation | Trabelsi, N.,Petit, P.,Manigand, C.,Langlois d'Estaintot, B.,Granier, T.,Chaudiere, J.,Gallois, B. Structural evidence for the inhibition of grape dihydroflavonol 4-reductase by flavonols Acta Crystallogr.,Sect.D, D64:883-891, 2008 Cited by PubMed: 18645237DOI: 10.1107/S0907444908017769 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.252 Å) |
Structure validation
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