Urate oxidase complexed with 8-azaxanthine under 1.0 MPa oxygen pressure

Summary for 2ZKA

DescriptorUricase, SODIUM ION, 8-AZAXANTHINE, ... (5 entities in total)
Functional Keywordsuric acid degradation, gaz-protein complex, t-fold domaun, acetylation, oxidoreductase, peroxisome, purine metabolism, tetramer
Biological sourceAspergillus flavus
Cellular locationPeroxisome Q00511
Total number of polymer chains1
Total molecular weight34391.68
Colloc'h, N.,Gabison, L.,Chiadmi, M.,Abraini, J.H.,Prange, T. (deposition date: 2008-03-13, release date: 2008-10-07, Last modification date: 2011-07-13)
Primary citation
Colloc'h, N.,Gabison, L.,Monard, G.,Altarsha, M.,Chiadmi, M.,Marassio, G.,Sopkova-de Oliveira Santos, J.,El Hajji, M.,Castro, B.,Abraini, J.H.,Prange, T.
Oxygen pressurized X-ray crystallography: probing the dioxygen binding site in cofactorless urate oxidase and implications for its catalytic mechanism.
Biophys.J., 95:2415-2422, 2008
PubMed: 18375516 (PDB entries with the same primary citation)
DOI: 10.1529/biophysj.107.122184
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.19030 2.7% 3.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-10-28