2ZKA

Urate oxidase complexed with 8-azaxanthine under 1.0 MPa oxygen pressure

Summary for 2ZKA

Related2ZKB
DescriptorUricase, SODIUM ION, 8-AZAXANTHINE, ... (5 entities in total)
Functional Keywordsuric acid degradation, gaz-protein complex, t-fold domaun, acetylation, oxidoreductase, peroxisome, purine metabolism, tetramer
Biological sourceAspergillus flavus
Cellular locationPeroxisome Q00511
Total number of polymer chains1
Total molecular weight34391.68
Authors
Colloc'h, N.,Gabison, L.,Chiadmi, M.,Abraini, J.H.,Prange, T. (deposition date: 2008-03-13, release date: 2008-10-07, Last modification date: 2011-07-13)
Primary citation
Colloc'h, N.,Gabison, L.,Monard, G.,Altarsha, M.,Chiadmi, M.,Marassio, G.,Sopkova-de Oliveira Santos, J.,El Hajji, M.,Castro, B.,Abraini, J.H.,Prange, T.
Oxygen pressurized X-ray crystallography: probing the dioxygen binding site in cofactorless urate oxidase and implications for its catalytic mechanism.
Biophys.J., 95:2415-2422, 2008
PubMed: 18375516 (PDB entries with the same primary citation)
DOI: 10.1529/biophysj.107.122184
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.61 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.190302.7%3.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution