2ZDN
Exploring trypsin S3 pocket
Summary for 2ZDN
| Entry DOI | 10.2210/pdb2zdn/pdb |
| Related | 1K1P 2ZDK 2ZDL 2ZDM |
| Related PRD ID | PRD_000606 |
| Descriptor | Cationic trypsin, CALCIUM ION, (S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclopentylpropanoyl)pyrrolidine-2-carboxamide, ... (5 entities in total) |
| Functional Keywords | hydrolase inhibitors, digestion, metal-binding, protease, secreted, serine protease, zymogen, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Bos taurus (Bovine) |
| Cellular location | Secreted, extracellular space: P00760 |
| Total number of polymer chains | 1 |
| Total formula weight | 23919.04 |
| Authors | Baum, B.,Brandt, T.,Heine, A.,Klebe, G. (deposition date: 2007-11-26, release date: 2008-10-14, Last modification date: 2023-11-01) |
| Primary citation | Brandt, T.,Holzmann, N.,Muley, L.,Khayat, M.,Wegscheid-Gerlach, C.,Baum, B.,Heine, A.,Hangauer, D.,Klebe, G. Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties J.Mol.Biol., 405:1170-1187, 2011 Cited by PubMed: 21111747DOI: 10.1016/j.jmb.2010.11.038 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.98 Å) |
Structure validation
Download full validation report
