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PDB: 497 件

5FXG
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BU of 5fxg by Molmil
GLUN1B-GLUN2B NMDA RECEPTOR IN ACTIVE CONFORMATION
分子名称: N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B
著者Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H.
登録日2016-03-02
公開日2016-05-11
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (6.8 Å)
主引用文献Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil.
Nature, 534, 2016
5EOH
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BU of 5eoh by Molmil
Crystal structure of murine neuroglobin at 270 MPa pressure
分子名称: Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Colloc'h, N, Girard, E, Vallone, B, Prange, T.
登録日2015-11-10
公開日2016-10-19
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Determinants of neuroglobin plasticity highlighted by joint coarse-grained simulations and high pressure crystallography.
Sci Rep, 7, 2017
5FXI
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BU of 5fxi by Molmil
GluN1b-GluN2B NMDA receptor structure in non-active-2 conformation
分子名称: N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B
著者Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H.
登録日2016-03-02
公開日2016-05-11
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (6.4 Å)
主引用文献Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil.
Nature, 534, 2016
5FST
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BU of 5fst by Molmil
Structure of lysozyme prepared by the 'soak-and-freeze' method under 100 bar of krypton pressure
分子名称: CHLORIDE ION, KRYPTON, LYSOZYME C, ...
著者Lafumat, B, Mueller-Dieckmann, C, Colloc'h, N, Prange, T, Royant, A, van der Linden, P, Carpentier, P.
登録日2016-01-07
公開日2016-10-26
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Gas-Sensitive Biological Crystals Processed in Pressurized Oxygen and Krypton Atmospheres: Deciphering Gas Channels in Proteins Using a Novel `Soak-and-Freeze' Methodology.
J.Appl.Crystallogr., 49, 2016
1ID9
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BU of 1id9 by Molmil
STRUCTURE OF THE HYBRID RNA/DNA R-GCUUCGGC-D[F]U IN PRESENCE OF RH(NH3)6+++
分子名称: 5'-R(*GP*CP*UP*UP*CP*GP*GP*C)-D(P*(UFP))-3', CHLORIDE ION, RHODIUM HEXAMINE ION
著者Cruse, W, Saludjian, P, Neuman, A, Prange, T.
登録日2001-04-04
公開日2001-04-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Destabilizing effect of a fluorouracil extra base in a hybrid RNA duplex compared with bromo and chloro analogues.
Acta Crystallogr.,Sect.D, 57, 2001
5EQM
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BU of 5eqm by Molmil
Crystal structure of murine neuroglobin at 310 MPa pressure
分子名称: Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Colloc'h, N, Girard, E, Vallone, B, Prange, T.
登録日2015-11-13
公開日2016-10-19
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Determinants of neuroglobin plasticity highlighted by joint coarse-grained simulations and high pressure crystallography.
Sci Rep, 7, 2017
2ZDL
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BU of 2zdl by Molmil
Exploring trypsin S3 pocket
分子名称: (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentyloxy)ethanoyl)pyrrolidine-2-carboxamide, CALCIUM ION, Cationic trypsin, ...
著者Baum, B, Brandt, T, Heine, A, Klebe, G.
登録日2007-11-26
公開日2008-10-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties
J.Mol.Biol., 405, 2011
2ZKA
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BU of 2zka by Molmil
Urate oxidase complexed with 8-azaxanthine under 1.0 MPa oxygen pressure
分子名称: 8-AZAXANTHINE, OXYGEN MOLECULE, SODIUM ION, ...
著者Colloc'h, N, Gabison, L, Chiadmi, M, Abraini, J.H, Prange, T.
登録日2008-03-13
公開日2008-10-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Oxygen pressurized X-ray crystallography: probing the dioxygen binding site in cofactorless urate oxidase and implications for its catalytic mechanism.
Biophys.J., 95, 2008
3BK8
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BU of 3bk8 by Molmil
Urate oxidase aza-xanthine complex in cyanide
分子名称: 8-AZAXANTHINE, SODIUM ION, Uricase
著者Gabison, L, Prange, T, Colloc'h, N, El Hajji, M, Castro, B, Chiadmi, M.
登録日2007-12-06
公開日2008-08-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural analysis of urate oxidase in complex with its natural substrate inhibited by cyanide: Mechanistic implications
Bmc Struct.Biol., 8, 2008
2IBA
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BU of 2iba by Molmil
Urate oxidase from Aspergillus flavus complexed with its inhibitor 8-azaxanthine
分子名称: 8-AZAXANTHINE, SODIUM ION, Uricase
著者Colloc'h, N, Retailleau, P, Sopkova-de Oliveira Santos, J, Prange, T.
登録日2006-09-11
公開日2007-02-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Protein Crystallography under Xenon and Nitrous Oxide Pressure: Comparison with In Vivo Pharmacology Studies and Implications for the Mechanism of Inhaled Anesthetic Action
Biophys.J., 92, 2007
1ISH
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BU of 1ish by Molmil
Crystal Structure Analysis of BST-1/CD157 complexed with ethenoNADP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ETHENO-NADP, bone marrow stromal cell antigen 1
著者Yamamoto-Katayama, S, Ariyoshi, M, Ishihara, K, Hirano, T, Jingami, H, Morikawa, K.
登録日2001-12-05
公開日2002-03-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystallographic studies on human BST-1/CD157 with ADP-ribosyl cyclase and NAD glycohydrolase activities.
J.Mol.Biol., 316, 2002
3PKT
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BU of 3pkt by Molmil
Urate oxidase under 2 MPa / 20 bars pressure of nitrous oxide
分子名称: 8-AZAXANTHINE, NITROUS OXIDE, SODIUM ION, ...
著者Marassio, G, Colloc'h, N, Prange, T, Abraini, J.H.
登録日2010-11-12
公開日2011-04-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Pressure-response analysis of anesthetic gases xenon and nitrous oxide on urate oxidase: a crystallographic study.
Faseb J., 25, 2011
3BXX
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BU of 3bxx by Molmil
Binding of two substrate analogue molecules to dihydroflavonol 4-reductase alters the functional geometry of the catalytic site
分子名称: 3,5,7,3',4'-PENTAHYDROXYFLAVONE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, dihydroflavonol 4-reductase
著者Trabelsi, N, Petit, P, Granier, T, Langlois d'Estaintot, B, Delrot, S, Gallois, B.
登録日2008-01-15
公開日2008-10-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural evidence for the inhibition of grape dihydroflavonol 4-reductase by flavonols
Acta Crystallogr.,Sect.D, D64, 2008
3PKS
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BU of 3pks by Molmil
Urate oxidase under 1.5 MPa / 15 bars pressure of nitrous oxide
分子名称: 8-AZAXANTHINE, NITROUS OXIDE, SODIUM ION, ...
著者Marassio, G, Colloc'h, N, Prange, T, Abraini, J.H.
登録日2010-11-12
公開日2011-04-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Pressure-response analysis of anesthetic gases xenon and nitrous oxide on urate oxidase: a crystallographic study.
Faseb J., 25, 2011
3PLI
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BU of 3pli by Molmil
Urate oxidase under 1.8 MPa / 18 bars pressure of equimolar mixture xenon : nitrous oxide
分子名称: 8-AZAXANTHINE, NITROUS OXIDE, SODIUM ION, ...
著者Marassio, G, Colloc'h, N, Prange, T, Abraini, J.H.
登録日2010-11-15
公開日2011-04-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Pressure-response analysis of anesthetic gases xenon and nitrous oxide on urate oxidase: a crystallographic study.
Faseb J., 25, 2011
3PK3
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BU of 3pk3 by Molmil
urate oxidase under 3.0 MPa / 30 bars pressure of nitrous oxide
分子名称: 8-AZAXANTHINE, NITROUS OXIDE, SODIUM ION, ...
著者Marassio, G, Colloc'h, N, Prange, T, Abraini, J.H.
登録日2010-11-11
公開日2011-04-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Pressure-response analysis of anesthetic gases xenon and nitrous oxide on urate oxidase: a crystallographic study.
Faseb J., 25, 2011
3PKF
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BU of 3pkf by Molmil
Urate oxidase under 0.2 MPa / 2 bars pressure of equimolar mixture of xenon and nitrous oxide
分子名称: 8-AZAXANTHINE, SODIUM ION, Uricase, ...
著者Marassio, G, Colloc'h, N, Prange, T, Abraini, J.H.
登録日2010-11-11
公開日2011-04-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Pressure-response analysis of anesthetic gases xenon and nitrous oxide on urate oxidase: a crystallographic study.
Faseb J., 25, 2011
3PLH
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BU of 3plh by Molmil
urate oxidase under 1.5 MPa / 15 bars pressure of equimolar mixture xenon : nitrous oxide
分子名称: 8-AZAXANTHINE, NITROUS OXIDE, SODIUM ION, ...
著者Marassio, G, Colloc'h, N, Prange, T, Abraini, J.H.
登録日2010-11-15
公開日2011-04-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Pressure-response analysis of anesthetic gases xenon and nitrous oxide on urate oxidase: a crystallographic study.
Faseb J., 25, 2011
4AJW
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BU of 4ajw by Molmil
Discovery and Optimization of New Benzimidazole- and Benzoxazole-Pyrimidone Selective PI3KBeta Inhibitors for the Treatment of Phosphatase and TENsin homologue (PTEN)-Deficient Cancers
分子名称: 2-[(1-methyl-1H-benzimidazol-2-yl)methyl]-6-morpholin-4-ylpyrimidin-4(3H)-one, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM
著者Certal, V, Halley, F, Virone-Oddos, A, Delorme, C, Karlsson, A, Rak, A, Thompson, F, Filoche-Romme, B, El-Ahmad, Y, Carry, J.C, Abecassis, P.Y, Lejeune, P, Bonnevaux, H, Nicolas, J.P, Bertrand, T, Marquette, J.P, Michot, N, Benard, T, Below, P, Vade, I, Chatreaux, F, Lebourg, G, Pilorge, F, Angouillant-Boniface, O, Louboutin, A, Lengauer, C, Schio, L.
登録日2012-02-20
公開日2012-05-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Discovery and Optimization of New Benzimidazole- and Benzoxazole-Pyrimidone Selective Pi3Kbeta Inhibitors for the Treatment of Phosphatase and Tensin Homologue (Pten)-Deficient Cancers.
J.Med.Chem., 55, 2012
5EV5
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BU of 5ev5 by Molmil
Crystal structure of murine neuroglobin mutant V101F at 150 MPa pressure
分子名称: Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Colloc'h, N, Girard, E, Vallone, B, Prange, T.
登録日2015-11-19
公開日2016-10-19
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Determinants of neuroglobin plasticity highlighted by joint coarse-grained simulations and high pressure crystallography.
Sci Rep, 7, 2017
3C1T
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BU of 3c1t by Molmil
Binding of two substrate analogue molecules to dihydroflavonol 4-reductase alters the functional geometry of the catalytic site
分子名称: 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, dihydroflavonol 4-reductase
著者Trabelsi, N, Petit, P, Granier, T, Langlois d'Estaintot, B, Delrot, S, Gallois, B.
登録日2008-01-24
公開日2008-02-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.252 Å)
主引用文献Structural evidence for the inhibition of grape dihydroflavonol 4-reductase by flavonols
Acta Crystallogr.,Sect.D, D64, 2008
2ZKB
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BU of 2zkb by Molmil
Urate oxidase complexed with 8-azaxanthine under 2.5 MPa oxygen pressure
分子名称: 8-AZAXANTHINE, OXYGEN MOLECULE, SODIUM ION, ...
著者Colloc'h, N, Gabison, L, Chiadmi, M, Abraini, J.H, Prange, T.
登録日2008-03-14
公開日2008-10-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Oxygen pressurized X-ray crystallography: probing the dioxygen binding site in cofactorless urate oxidase and implications for its catalytic mechanism.
Biophys.J., 95, 2008
6CNA
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BU of 6cna by Molmil
GluN1-GluN2B NMDA receptors with exon 5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
著者Furukawa, H, Grant, T, Grigorieff, N.
登録日2018-03-07
公開日2018-10-03
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural Mechanism of Functional Modulation by Gene Splicing in NMDA Receptors.
Neuron, 98, 2018
2ZDN
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BU of 2zdn by Molmil
Exploring trypsin S3 pocket
分子名称: (S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclopentylpropanoyl)pyrrolidine-2-carboxamide, CALCIUM ION, Cationic trypsin, ...
著者Baum, B, Brandt, T, Heine, A, Klebe, G.
登録日2007-11-26
公開日2008-10-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties
J.Mol.Biol., 405, 2011
1LCN
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BU of 1lcn by Molmil
Monoclinic hen egg white lysozyme, thiocyanate complex
分子名称: PROTEIN (LYSOZYME), THIOCYANATE ION
著者Hamiaux, C, Prange, T, Ducruix, A, Vaney, M.C.
登録日1998-10-27
公開日1998-11-04
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Structural effects of monovalent anions on polymorphic lysozyme crystals.
Acta Crystallogr.,Sect.D, 57, 2001

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