5D75
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5d75 by Molmil](/molmil-images/mine/5d75) | Crystal structure of Human FKBD25 in complex with FK506 | 分子名称: | 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500), Peptidyl-prolyl cis-trans isomerase FKBP3 | 著者 | Rajan, S, Prakash, A, Yoon, H.S. | 登録日 | 2015-08-13 | 公開日 | 2016-04-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Crystal structure of the FK506 binding domain of human FKBP25 in complex with FK506. Protein Sci., 25, 2016
|
|
1LJX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ljx by Molmil](/molmil-images/mine/1ljx) | THE STRUCTURE OF D(TPGPCPGPCPA)2 AT 293K: COMPARISON OF THE EFFECT OF SEQUENCE AND TEMPERATURE | 分子名称: | 5'-D(*TP*GP*CP*GP*CP*A)-3', MAGNESIUM ION | 著者 | Thiyagarajan, S, Satheesh Kumar, P, Rajan, S.S, Gautham, N. | 登録日 | 2002-04-23 | 公開日 | 2002-05-03 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Structure of d(TGCGCA)2 at 293 K: comparison of the effects of sequence and temperature. Acta Crystallogr.,Sect.D, 58, 2002
|
|
1XA2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xa2 by Molmil](/molmil-images/mine/1xa2) | |
1XAM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xam by Molmil](/molmil-images/mine/1xam) | Cobalt hexammine induced tautameric shift in Z-DNA: structure of d(CGCGCA).d(TGCGCG) in two crystal forms. | 分子名称: | CGCGCA, COBALT HEXAMMINE(III), TG, ... | 著者 | Thiyagarajan, S, Rajan, S.S, Gautham, N. | 登録日 | 2004-08-26 | 公開日 | 2004-11-16 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Cobalt hexammine induced tautomeric shift in Z-DNA: the structure of d(CGCGCA)*d(TGCGCG) in two crystal forms. Nucleic Acids Res., 32, 2004
|
|
3Q95
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3q95 by Molmil](/molmil-images/mine/3q95) | Crystal structure of human estrogen receptor alpha LBD in complex with GRIP peptide and estriol | 分子名称: | CHLORIDE ION, ESTRIOL, Estrogen receptor, ... | 著者 | Rajan, S.S, Kim, Y, Vanek, K, Joachimiak, A, Greene, G.L. | 登録日 | 2011-01-07 | 公開日 | 2012-01-11 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structure of human estrogen receptor alpha LBD in complex with GRIP peptide and Estriol TO BE PUBLISHED
|
|
4MGV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mgv by Molmil](/molmil-images/mine/4mgv) | |
2B1V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2b1v by Molmil](/molmil-images/mine/2b1v) | Human estrogen receptor alpha ligand-binding domain in complex with OBCP-1M and a glucocorticoid receptor interacting protein 1 NR box II peptide | 分子名称: | 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-8-METHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL, Estrogen receptor, Nuclear receptor coactivator 2 | 著者 | Rajan, S.S, Hsieh, R.W, Sharma, S.K, Greene, G.L. | 登録日 | 2005-09-16 | 公開日 | 2006-05-09 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity. J.Biol.Chem., 281, 2006
|
|
2B1Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2b1z by Molmil](/molmil-images/mine/2b1z) | Human estrogen receptor alpha ligand-binding domain in complex with 17methyl-17alpha-dihydroequilenin and a glucoc interacting protein 1 NR box II peptide | 分子名称: | 17-METHYL-17-ALPHA-DIHYDROEQUILENIN, Estrogen receptor, Nuclear receptor coactivator 2 | 著者 | Rajan, S.S, Hsieh, R.W, Sharma, S.K, Greene, G.L. | 登録日 | 2005-09-16 | 公開日 | 2006-09-19 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Molecular characterization of a B-ring unsaturated estrogen: implications for conjugated equine estrogen components of premarin. Steroids, 73, 2008
|
|
1ZKY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zky by Molmil](/molmil-images/mine/1zky) | Human Estrogen Receptor Alpha Ligand-Binding Domain In Complex With OBCP-3M and A Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide | 分子名称: | 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-6,8,9-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL, Estrogen receptor, Nuclear receptor coactivator 2 | 著者 | Rajan, S.S, Hsieh, R.W, Sharma, S.K, Hahm, J.B, Nettles, K.W, Greene, G.L. | 登録日 | 2005-05-04 | 公開日 | 2006-05-09 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity. J.Biol.Chem., 281, 2006
|
|
3HM1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hm1 by Molmil](/molmil-images/mine/3hm1) | Crystal structure of human Estrogen Receptor Alpha Ligand-Binding Domain in complex with a Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide and estrone ((8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one) | 分子名称: | (9beta,13alpha)-3-hydroxyestra-1,3,5(10)-trien-17-one, Estrogen receptor, Nuclear receptor coactivator 2 | 著者 | Rajan, S.S, Kim, Y, Vanek, K, Liwanag, M, Joachimiak, A, Greene, G.L. | 登録日 | 2009-05-28 | 公開日 | 2010-06-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Crystal structure of human Estrogen Receptor Alpha Ligand-Binding Domain in complex with a Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide and estrone ((8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15, 16-octahydro-6H-cyclopenta[a]phenanthren-17-one) To be Published
|
|
3L03
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3l03 by Molmil](/molmil-images/mine/3l03) | Crystal Structure of human Estrogen Receptor alpha Ligand-Binding Domain in complex with a Glucocorticoid Receptor Interacting Protein 1 Nr Box II peptide and Estetrol (Estra-1,3,5(10)-triene-3,15 alpha,16alpha,17beta-tetrol) | 分子名称: | (14beta,15alpha,16alpha,17alpha)-estra-1,3,5(10)-triene-3,15,16,17-tetrol, CHLORIDE ION, Estrogen receptor, ... | 著者 | Rajan, S.S, Kim, Y, Vanek, K, Joachimiak, A, Greene, G.L. | 登録日 | 2009-12-09 | 公開日 | 2010-12-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.896 Å) | 主引用文献 | Crystal Structure of human Estrogen Receptor alpha Ligand-Binding Domain
in complex with a Glucocorticoid Receptor Interacting Protein 1 Nr Box II
peptide and Estra-1,3,5(10)-triene-3,15 alpha,16alpha,17beta-tetrol To be Published
|
|
3HLV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hlv by Molmil](/molmil-images/mine/3hlv) | Crystal structure of human Estrogen Receptor Alpha Ligand-Binding Domain in complex with a Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide and 16-alpha-hydroxy-estrone ((8S,9R,13S,14R,16R)-3,16-dihydroxy-13-methyl-7,8,9,11,12,14,15, 16-octahydro-6H-cyclopenta[a]phenanthren-17-one | 分子名称: | (9beta,13alpha,16beta)-3,16-dihydroxyestra-1,3,5(10)-trien-17-one, Estrogen receptor, Nuclear receptor coactivator 2 | 著者 | Rajan, S.S, Kim, Y, Vanek, K, Joachimiak, A, Greene, G.L. | 登録日 | 2009-05-28 | 公開日 | 2010-06-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of human alphaER-LBD in complex with GRIP peptide and 16alpha-hydroxyestrone To be Published
|
|
1TO9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1to9 by Molmil](/molmil-images/mine/1to9) | |
1U8X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1u8x by Molmil](/molmil-images/mine/1u8x) | CRYSTAL STRUCTURE OF GLVA FROM BACILLUS SUBTILIS, A METAL-REQUIRING, NAD-DEPENDENT 6-PHOSPHO-ALPHA-GLUCOSIDASE | 分子名称: | 6-O-phosphono-alpha-D-glucopyranose, MANGANESE (II) ION, Maltose-6'-phosphate glucosidase, ... | 著者 | Rajan, S.S, Yang, X, Collart, F, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2004-08-09 | 公開日 | 2004-08-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Novel Catalytic Mechanism of Glycoside Hydrolysis Based on the Structure of an NAD(+)/Mn(2+)-Dependent Phospho-alpha-Glucosidase from Bacillus subtilis. STRUCTURE, 12, 2004
|
|
1RXQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1rxq by Molmil](/molmil-images/mine/1rxq) | YfiT from Bacillus subtilis is a probable metal-dependent hydrolase with an unusual four-helix bundle topology | 分子名称: | ALANINE, GLUTAMIC ACID, GLYCINE, ... | 著者 | Rajan, S.S, Yang, X, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2003-12-18 | 公開日 | 2004-07-20 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | YfiT from Bacillus subtilis Is a Probable Metal-Dependent Hydrolase with an Unusual Four-Helix Bundle Topology Biochemistry, 43, 2004
|
|
2FAI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fai by Molmil](/molmil-images/mine/2fai) | Human Estrogen Receptor Alpha Ligand-Binding Domain In Complex With OBCP-2M and A Glucocorticoid Receptor Interacting Protein 1 NR Box II Peptide | 分子名称: | 4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL, Estrogen receptor, Nuclear receptor coactivator 2 | 著者 | Rajan, S.S, Hsieh, R.W, Sharma, S.K, Greene, G.L. | 登録日 | 2005-12-07 | 公開日 | 2006-05-09 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity. J.Biol.Chem., 281, 2006
|
|
2B23
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2b23 by Molmil](/molmil-images/mine/2b23) | Human estrogen receptor alpha ligand-binding domain and a glucocorticoid receptor-interacting protein 1 NR box II peptide | 分子名称: | Estrogen receptor, Nuclear receptor coactivator 2 | 著者 | Rajan, S.S, Hsieh, R.W, Sharma, S.K, Greene, G.L. | 登録日 | 2005-09-16 | 公開日 | 2006-09-19 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses Nat.Chem.Biol., 4, 2008
|
|
2G44
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2g44 by Molmil](/molmil-images/mine/2g44) | Human Estrogen Receptor Alpha Ligand-Binding Domain In Complex With OBCP-1M-G and A Glucocorticoid Receptor Interacting Protein 1 NR Box II Peptide | 分子名称: | 4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL, Estrogen receptor, Nuclear receptor coactivator 2 | 著者 | Rajan, S.S, Hsieh, R.W, Sharma, S.K, Greene, G.L. | 登録日 | 2006-02-21 | 公開日 | 2007-01-09 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Discovery and characterization of novel estrogen
receptor agonist ligands and development of biochips for
nuclear receptor drug discovery Thesis, 2006
|
|
2G5O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2g5o by Molmil](/molmil-images/mine/2g5o) | Human estrogen receptor alpha ligand-binding domain in complex with 2-(but-1-enyl)-17beta-estradiol and a glucocorticoid receptor interacting protein 1 NR BOX II Peptide | 分子名称: | (9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL, Estrogen receptor, Nuclear receptor coactivator 2 | 著者 | Rajan, S.S, Hsieh, R.W, Sharma, S.K, Greene, G.L. | 登録日 | 2006-02-23 | 公開日 | 2007-03-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Human estrogen receptor alpha ligand-binding domain in complex with 2-(but-1-enyl)-17beta-estradiol and a glucocorticoid receptor interacting protein 1 NR BOX II Peptide To be Published
|
|
2H7H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2h7h by Molmil](/molmil-images/mine/2h7h) | |
2OCF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ocf by Molmil](/molmil-images/mine/2ocf) | Human estrogen receptor alpha ligand-binding domain in complex with estradiol and the E2#23 FN3 monobody | 分子名称: | ESTRADIOL, Estrogen receptor, Fibronectin | 著者 | Rajan, S.S, Kuruvilla, S.M, Sharma, S.K, Kim, Y, Huang, J, Koide, A, Koide, S, Joachimiak, A, Greene, G.L. | 登録日 | 2006-12-20 | 公開日 | 2007-11-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Probing protein conformational changes in living cells by using designer binding proteins: application to the estrogen receptor. Proc.Natl.Acad.Sci.USA, 99, 2002
|
|
4Z0X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4z0x by Molmil](/molmil-images/mine/4z0x) | |
3V7K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3v7k by Molmil](/molmil-images/mine/3v7k) | |
3V7L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3v7l by Molmil](/molmil-images/mine/3v7l) | Apo Structure of Rat DNA polymerase beta K72E variant | 分子名称: | CHLORIDE ION, DNA polymerase beta, SODIUM ION, ... | 著者 | Rangarajan, S, Jaeger, J. | 登録日 | 2011-12-21 | 公開日 | 2013-01-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Crystallographic studies of K72E mutant DNA polymerase explain loss of lyase function and reveal changes in the overall conformational state of the polymerase domain To be Published
|
|
3V7J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3v7j by Molmil](/molmil-images/mine/3v7j) | |