2B1Z

Human estrogen receptor alpha ligand-binding domain in complex with 17methyl-17alpha-dihydroequilenin and a glucoc interacting protein 1 NR box II peptide

Summary for 2B1Z

• Entry DOI: 10.2210/pdb2b1z/pdb
• Related: 2B1V 2B23
• Descriptor: Estrogen receptor, Nuclear receptor coactivator 2, 17-METHYL-17-ALPHA-DIHYDROEQUILENIN, ... (4 entities in total)
• Functional Keywords: estrogen receptor, lbd, grip peptide, hormone-growth factor receptor complex, hormone/growth factor receptor
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 62780.26

Authors

Rajan, S.S.,Hsieh, R.W.,Sharma, S.K.,Greene, G.L. (deposition date: 2005-09-16, release date: 2006-09-19, Last modification date: 2023-08-23)

• Primary citation: Hsieh, R.W.,Rajan, S.S.,Sharma, S.K.,Greene, G.L.; Molecular characterization of a B-ring unsaturated estrogen: implications for conjugated equine estrogen components of premarin.; Steroids, 73:59-68, 2008; PubMed: 17949766; DOI: 10.1016/j.steroids.2007.08.014

Experimental method

X-RAY DIFFRACTION (1.78 Å)