2B1Z
Human estrogen receptor alpha ligand-binding domain in complex with 17methyl-17alpha-dihydroequilenin and a glucoc interacting protein 1 NR box II peptide
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 17M A 201 |
| Chain | Residue |
| A | HOH8 |
| A | GLU353 |
| A | LEU387 |
| A | ARG394 |
| A | PHE404 |
| A | MET421 |
| A | HIS524 |
| A | LEU525 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 17M B 202 |
| Chain | Residue |
| B | GLU353 |
| B | LEU387 |
| B | ARG394 |
| B | MET421 |
| B | HIS524 |
| B | LEU525 |
| B | HOH42 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine; by Tyr-kinases => ECO:0000269|PubMed:7539106 |
| Chain | Residue | Details |
| A | SER537 | |
| B | SER537 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000250 |
| Chain | Residue | Details |
| A | CYS447 | |
| B | CYS447 |
