3L03

Crystal Structure of human Estrogen Receptor alpha Ligand-Binding Domain in complex with a Glucocorticoid Receptor Interacting Protein 1 Nr Box II peptide and Estetrol (Estra-1,3,5(10)-triene-3,15 alpha,16alpha,17beta-tetrol)

Summary for 3L03

• Entry DOI: 10.2210/pdb3l03/pdb
• Descriptor: Estrogen receptor, Nuclear receptor coactivator 2, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: estrogen receptor, lbd, grip peptide, estetrol, dna-binding, glycoprotein, lipid-binding, metal-binding, nucleus, phosphoprotein, receptor, steroid-binding, transcription, transcription regulation, zinc-finger, activator
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 61934.60

Authors

Rajan, S.S.,Kim, Y.,Vanek, K.,Joachimiak, A.,Greene, G.L. (deposition date: 2009-12-09, release date: 2010-12-08, Last modification date: 2023-09-06)

• Primary citation: Rajan, S.S.,Kim, Y.,Vanek, K.,Joachimiak, A.,Greene, G.L.; Crystal Structure of human Estrogen Receptor alpha Ligand-Binding Domain in complex with a Glucocorticoid Receptor Interacting Protein 1 Nr Box II peptide and Estra-1,3,5(10)-triene-3,15 alpha,16alpha,17beta-tetrol; To be Published,

Experimental method

X-RAY DIFFRACTION (1.896 Å)