6P6A
 
 | | Structure of Mouse Importin alpha - NIT2 NLS peptide complex | | 分子名称: | Importin subunit alpha-1, Nitrogen catabolic enzyme regulatory protein | | 著者 | Bernardes, N.E, Fukuda, C.A, Silva, T.D, Oliveira, H.C, Fontes, M.R.M. | | 登録日 | 2019-06-03 | | 公開日 | 2020-01-29 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.151 Å) | | 主引用文献 | Comparative study of the interactions between fungal transcription factor nuclear localization sequences with mammalian and fungal importin-alpha.
Sci Rep, 10, 2020
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5O68
 | | Crystal Structure of the Pseudomonas functional amyloid secretion protein FapF - R157A mutant | | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, FapF, LAURYL DIMETHYLAMINE-N-OXIDE | | 著者 | Rouse, S.L, Hare, S, Lambert, S, Morgan, R.M.L, Hawthorne, W.J, Berry, J, Matthews, S.J. | | 登録日 | 2017-06-05 | | 公開日 | 2017-08-23 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.08 Å) | | 主引用文献 | A new class of hybrid secretion system is employed in Pseudomonas amyloid biogenesis.
Nat Commun, 8, 2017
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5OQA
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6JN2
 | | Crystal structure of the coiled-coil domains of human DOT1L in complex with AF10 | | 分子名称: | Histone-lysine N-methyltransferase, H3 lysine-79 specific, Protein AF-10 | | 著者 | Song, X, Wang, M, Yang, N, Xu, R.M. | | 登録日 | 2019-03-13 | | 公開日 | 2019-09-18 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | A higher-order configuration of the heterodimeric DOT1L-AF10 coiled-coil domains potentiates their leukemogenenic activity.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6PDN
 | | Human PIM1 bound to benzothiophene inhibitor 292 | | 分子名称: | 4-{5-[(3-aminopropyl)carbamoyl]thiophen-2-yl}-1-benzothiophene-2-carboxylic acid, GLYCEROL, Serine/threonine-protein kinase pim-1, ... | | 著者 | Godoi, P.H.C, Santiago, A.S, Fala, A.M, Ramos, P.Z, Sriranganadane, D, Mascarello, A, Segretti, N, Azevedo, H, Guimaraes, C.R.W, Arruda, P, Elkins, J.M, Counago, R.M, Structural Genomics Consortium (SGC) | | 登録日 | 2019-06-19 | | 公開日 | 2019-07-24 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Human PIM1
To Be Published
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6PDO
 | | Human PIM1 bound to benzothiophene inhibitor 354 | | 分子名称: | 4-{5-[(3-aminopropyl)carbamoyl]thiophen-2-yl}-1-benzothiophene-2-carboxamide, Peptide, Serine/threonine-protein kinase pim-1 | | 著者 | Godoi, P.H.C, Santiago, A.S, Fala, A.M, Ramos, P.Z, Sriranganadane, D, Mascarello, A, Segretti, N, Azevedo, H, Guimaraes, C.R.W, Arruda, P, Elkins, J.M, Counago, R.M, Structural Genomics Consortium (SGC) | | 登録日 | 2019-06-19 | | 公開日 | 2019-07-24 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Human PIM1
To Be Published
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8AYB
 | | anammox-specific FabZ from Scalindua brodae | | 分子名称: | Beta-hydroxyacyl-(Acyl-carrier-protein) dehydratase | | 著者 | Dietl, A, Barends, T.R.M. | | 登録日 | 2022-09-02 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structures of an unusual 3-hydroxyacyl dehydratase (FabZ) from a ladderane-producing organism with an unexpected substrate preference.
J.Biol.Chem., 299, 2023
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6HAU
 | | KSHV PAN RNA Mta-response element fragment complexed with the globular domain of herpesvirus saimiri ORF57 | | 分子名称: | ACETATE ION, MRE fragment of PAN RNA, ZINC ION, ... | | 著者 | Tunnicliffe, R.B, Levy, C, Ruiz Nivia, H.D, Sandri-Goldin, R.M, Golovanov, A.P. | | 登録日 | 2018-08-08 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Structural identification of conserved RNA binding sites in herpesvirus ORF57 homologs: implications for PAN RNA recognition.
Nucleic Acids Res., 47, 2019
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6PJJ
 | | Human PRPF4B bound to benzothiophene inhibitor 224 | | 分子名称: | 1,2-ETHANEDIOL, 4-(5-{[(3-aminophenyl)methyl]carbamoyl}thiophen-2-yl)-1-benzothiophene-2-carboxamide, PHOSPHATE ION, ... | | 著者 | Godoi, P.H.C, Santiago, A.S, Fala, A.M, Ramos, P.Z, Sriranganadane, D, Mascarello, A, Segretti, N, Azevedo, H, Guimaraes, C.R.W, Arruda, P, Elkins, J.M, Counago, R.M, Structural Genomics Consortium (SGC) | | 登録日 | 2019-06-28 | | 公開日 | 2019-08-28 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | to be published
To Be Published
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6HL8
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8AFI
 | | GABARAP in complex with LIR motif of HsATG3 | | 分子名称: | ACETATE ION, GLYCEROL, Gamma-aminobutyric acid receptor-associated protein, ... | | 著者 | Farnung, J, Benoit, R.M, Corn, J.E, Bode, J.W. | | 登録日 | 2022-07-18 | | 公開日 | 2023-05-10 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | | 主引用文献 | Semisynthetic LC3 Probes for Autophagy Pathways Reveal a Noncanonical LC3 Interacting Region Motif Crucial for the Enzymatic Activity of Human ATG3.
Acs Cent.Sci., 9, 2023
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6PDI
 | | Human PIM1 bound to benzothiophene inhibitor 224 | | 分子名称: | 1,2-ETHANEDIOL, 4-(5-{[(3-aminophenyl)methyl]carbamoyl}thiophen-2-yl)-1-benzothiophene-2-carboxamide, GLYCEROL, ... | | 著者 | Godoi, P.H.C, Fala, A.M, Santiago, A.S, Ramos, P.Z, Sriranganadane, D, Mascarello, A, Segretti, N, Azevedo, H, Guimaraes, C.R.W, Arruda, P, Elkins, J.M, Counago, R.M, Structural Genomics Consortium (SGC) | | 登録日 | 2019-06-19 | | 公開日 | 2019-07-24 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Human PIM1
To Be Published
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6HAL
 | | Human carbonmonoxy hemoglobin SFX dataset | | 分子名称: | CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | | 著者 | Doak, B, Gorel, A, Foucar, L, Barends, T.R.M, Gruenbein, M.L, Hilpert, M, Kloos, M, Nass Kovacs, G, Roome, C.M, Shoeman, R.L, Stricker, M, Tono, K, You, D, Ueda, K, Sherrell, D.A, Owen, R.L, Schlichting, I. | | 登録日 | 2018-08-07 | | 公開日 | 2018-10-17 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystallography on a chip - without the chip: sheet-on-sheet sandwich.
Acta Crystallogr D Struct Biol, 74, 2018
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6PDP
 | | Human PIM1 bound to benzothiophene inhibitor 379 | | 分子名称: | 5-[2-(acetylamino)-1-benzothiophen-4-yl]-N-cyclopropylthiophene-2-carboxamide, Peptide, SULFATE ION, ... | | 著者 | Godoi, P.H.C, Sriranganadane, D, Santiago, A.S, Fala, A.M, Ramos, P.Z, Mascarello, A, Segretti, N, Azevedo, H, Guimaraes, C.R.W, Arruda, P, Elkins, J.M, Counago, R.M, Structural Genomics Consortium (SGC) | | 登録日 | 2019-06-19 | | 公開日 | 2019-07-24 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Human PIM1
To Be Published
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5O8A
 | | Crystal Structure of rsEGFP2 in the non-fluorescent off-state determined by SFX | | 分子名称: | Green fluorescent protein | | 著者 | Coquelle, N, Sliwa, M, Woodhouse, J, Schiro, G, Adam, V, Aquila, A, Barends, T.R.M, Boutet, S, Byrdin, M, Carbajo, S, De la Mora, E, Doak, R.B, Feliks, M, Fieschi, F, Foucar, L, Guillon, V, Hilpert, M, Hunter, M, Jakobs, S, Koglin, J.E, Kovacsova, G, Lane, T.J, Levy, B, Liang, M, Nass, K, Ridard, J, Robinson, J.S, Roome, C.M, Ruckebusch, C, Seaberg, M, Thepaut, M, Cammarata, M, Demachy, I, Field, M, Shoeman, R.L, Bourgeois, D, Colletier, J.P, Schlichting, I, Weik, M. | | 登録日 | 2017-06-12 | | 公開日 | 2017-09-27 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Chromophore twisting in the excited state of a photoswitchable fluorescent protein captured by time-resolved serial femtosecond crystallography.
Nat Chem, 10, 2018
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5O8I
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7A7D
 | | Cadherin fit into cryo-ET map | | 分子名称: | Desmocollin-2, Desmoglein-2 | | 著者 | Sikora, M, Ermel, U.H, Seybold, A, Kunz, M, Calloni, G, Reitz, J, Vabulas, R.M, Hummer, G, Frangakis, A.S. | | 登録日 | 2020-08-28 | | 公開日 | 2020-12-23 | | 実験手法 | ELECTRON MICROSCOPY (26 Å) | | 主引用文献 | Desmosome architecture derived from molecular dynamics simulations and cryo-electron tomography.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6PV8
 | | Human alpha3beta4 nicotinic acetylcholine receptor in complex with AT-1001 | | 分子名称: | (3-endo)-N-(2-bromophenyl)-9-methyl-9-azabicyclo[3.3.1]nonan-3-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Gharpure, A, Teng, J, Zhuang, Y, Noviello, C.M, Walsh, R.M, Cabuco, R, Howard, R.J, Zaveri, N.T, Lindahl, E, Hibbs, R.E. | | 登録日 | 2019-07-19 | | 公開日 | 2019-09-11 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | | 主引用文献 | Agonist Selectivity and Ion Permeation in the alpha 3 beta 4 Ganglionic Nicotinic Receptor.
Neuron, 104, 2019
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7QRH
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6PV7
 | | Human alpha3beta4 nicotinic acetylcholine receptor in complex with nicotine | | 分子名称: | (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Gharpure, A, Teng, J, Zhuang, Y, Noviello, C.M, Walsh, R.M, Cabuco, R, Howard, R.J, Zaveri, N.T, Lindahl, E, Hibbs, R.E. | | 登録日 | 2019-07-19 | | 公開日 | 2019-09-11 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.34 Å) | | 主引用文献 | Agonist Selectivity and Ion Permeation in the alpha 3 beta 4 Ganglionic Nicotinic Receptor.
Neuron, 104, 2019
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6PW3
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6HR1
 | | Crystal structure of the YFPnano fusion protein | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, GLYCEROL, ... | | 著者 | Benoit, R.M. | | 登録日 | 2018-09-26 | | 公開日 | 2020-04-08 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | | 主引用文献 | Chimeric single alpha-helical domains as rigid fusion protein connections for protein nanotechnology and structural biology.
Structure, 2021
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6HAT
 | | Globular domain of herpesvirus saimiri ORF57 | | 分子名称: | ACETATE ION, ZINC ION, mRNA export factor ICP27 homolog | | 著者 | Tunnicliffe, R.B, Levy, C, Ruiz Nivia, H.D, Sandri-Goldin, R.M, Golovanov, A.P. | | 登録日 | 2018-08-08 | | 公開日 | 2018-11-21 | | 最終更新日 | 2022-03-30 | | 実験手法 | X-RAY DIFFRACTION (1.856 Å) | | 主引用文献 | Structural identification of conserved RNA binding sites in herpesvirus ORF57 homologs: implications for PAN RNA recognition.
Nucleic Acids Res., 47, 2019
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7B2M
 | | Cryo-EM structure of complement C4b in complex with nanobody E3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-C4b nanobody E3, Complement C4 alpha chain, ... | | 著者 | Oosterheert, W, De la O Becerra, K.I, van den Bos, R.M, Gros, P. | | 登録日 | 2020-11-27 | | 公開日 | 2022-03-02 | | 最終更新日 | 2022-05-04 | | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | | 主引用文献 | Multifaceted Activities of Seven Nanobodies against Complement C4b.
J Immunol., 208, 2022
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6HIF
 | | Kuenenia stuttgartiensis hydrazine dehydrogenase complex | | 分子名称: | GLYCEROL, HEME C, Hydrazine dehydrogenase, ... | | 著者 | Akram, M, Dietl, A, Mersdorf, U, Prinz, S, Maalcke, W, Keltjens, J, Ferousi, C, de Almeida, N.M, Reimann, J, Kartal, B, Jetten, M.S.M, Parey, K, Barends, T.R.M. | | 登録日 | 2018-08-29 | | 公開日 | 2019-04-17 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | A 192-heme electron transfer network in the hydrazine dehydrogenase complex.
Sci Adv, 5, 2019
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