6PDI

Human PIM1 bound to benzothiophene inhibitor 224

Summary for 6PDI

• Entry DOI: 10.2210/pdb6pdi/pdb
• Related: 6PCW
• Descriptor: Serine/threonine-protein kinase pim-1, Peptide, 4-(5-{[(3-aminophenyl)methyl]carbamoyl}thiophen-2-yl)-1-benzothiophene-2-carboxamide, ... (6 entities in total)
• Functional Keywords: proto-oncogene serine/threonine-protein kinase pim-1, structural genomics, structural genomics consortium, sgc, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 38083.37

Authors

Godoi, P.H.C.,Fala, A.M.,Santiago, A.S.,Ramos, P.Z.,Sriranganadane, D.,Mascarello, A.,Segretti, N.,Azevedo, H.,Guimaraes, C.R.W.,Arruda, P.,Elkins, J.M.,Counago, R.M.,Structural Genomics Consortium (SGC) (deposition date: 2019-06-19, release date: 2019-07-24, Last modification date: 2024-03-13)

• Primary citation: Godoi, P.H.C.,Santiago, A.S.,Fala, A.M.,Ramos, P.Z.,Sriranganadane, D.,Mascarello, A.,Segretti, N.,Azevedo, H.,Guimaraes, C.R.W.,Arruda, P.,Elkins, J.M.,Counago, R.M.; Human PIM1; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)