6PDI
Human PIM1 bound to benzothiophene inhibitor 224
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Serine/threonine-protein kinase pim-1 | polymer | 313 | 35590.5 | 1 | UniProt (P11309) Pfam (PF00069) In PDB | Homo sapiens (Human) | |
| 2 | B | Peptide | polymer | 14 | 1592.8 | 1 | synthetic construct | ||
| 3 | A | 4-(5-{[(3-aminophenyl)methyl]carbamoyl}thiophen-2-yl)-1-benzothiophene-2-carboxamide | non-polymer | 407.5 | 1 | Chemie (OCJ) | |||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 6 | water | water | 18.0 | 144 | Chemie (HOH) |
Sequence modifications
A: 1 - 312 (UniProt: P11309)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Gly 250 | Arg 250 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37183.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 900.0 | |
| All* | Total formula weight | 38083.4 |
