6PJJ

Human PRPF4B bound to benzothiophene inhibitor 224

Summary for 6PJJ

• Entry DOI: 10.2210/pdb6pjj/pdb
• Descriptor: Serine/threonine-protein kinase PRP4 homolog, 4-(5-{[(3-aminophenyl)methyl]carbamoyl}thiophen-2-yl)-1-benzothiophene-2-carboxamide, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: serine/threonine-protein kinase prp4 homolog, structural genomics consortium, sgc, transferase, splicing kinase prpf4b, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 166739.80

Authors

Godoi, P.H.C.,Santiago, A.S.,Fala, A.M.,Ramos, P.Z.,Sriranganadane, D.,Mascarello, A.,Segretti, N.,Azevedo, H.,Guimaraes, C.R.W.,Arruda, P.,Elkins, J.M.,Counago, R.M.,Structural Genomics Consortium (SGC) (deposition date: 2019-06-28, release date: 2019-08-28, Last modification date: 2024-10-23)

• Primary citation: Godoi, P.H.C.,Santiago, A.S.,Fala, A.M.,Ramos, P.Z.,Sriranganadane, D.,Mascarello, A.,Segretti, N.,Azevedo, H.,Guimaraes, C.R.W.,Arruda, P.,Elkins, J.M.,Counago, R.M.; to be published; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)