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6PW3

LARP1 DM15 FYRE (F844Y, R847E) mutant bound to m7GpppG dinucleotide (capG)

Summary for 6PW3
Entry DOI10.2210/pdb6pw3/pdb
DescriptorLa-related protein 1, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordsheat-like, cap-binding, top mrna, translation regulation, rna binding protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total formula weight80047.99
Authors
Lahr, R.M.,Berman, A.J. (deposition date: 2019-07-22, release date: 2019-11-06, Last modification date: 2023-10-11)
Primary citationCassidy, K.C.,Lahr, R.M.,Kaminsky, J.C.,Mack, S.,Fonseca, B.D.,Das, S.R.,Berman, A.J.,Durrant, J.D.
Capturing the Mechanism Underlying TOP mRNA Binding to LARP1.
Structure, 27:1771-, 2019
Cited by
PubMed: 31676287
DOI: 10.1016/j.str.2019.10.006
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.34 Å)
Structure validation

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