6PW3
LARP1 DM15 FYRE (F844Y, R847E) mutant bound to m7GpppG dinucleotide (capG)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000339 | molecular_function | RNA cap binding |
| A | 0048255 | biological_process | mRNA stabilization |
| B | 0000339 | molecular_function | RNA cap binding |
| B | 0048255 | biological_process | mRNA stabilization |
| C | 0000339 | molecular_function | RNA cap binding |
| C | 0048255 | biological_process | mRNA stabilization |
| D | 0000339 | molecular_function | RNA cap binding |
| D | 0048255 | biological_process | mRNA stabilization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue GTG C 1001 |
| Chain | Residue |
| C | SER843 |
| C | LYS915 |
| C | ALA918 |
| C | TYR922 |
| C | TYR844 |
| C | GLU847 |
| C | ARG879 |
| C | SER882 |
| C | TYR883 |
| C | GLU886 |
| C | TYR911 |
| C | GLU914 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 1001 |
| Chain | Residue |
| A | ARG871 |
| A | GLU875 |
| A | TYR911 |
| B | GLU875 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | binding site for residue GTG B 1001 |
| Chain | Residue |
| A | SER843 |
| A | TYR844 |
| A | GLU847 |
| A | ARG879 |
| A | TYR883 |
| A | TYR911 |
| A | GLU914 |
| A | LYS915 |
| B | SER843 |
| B | TYR844 |
| B | GLU847 |
| B | ARG879 |
| B | TYR883 |
| B | TYR911 |
| B | GLU914 |
| B | LYS915 |
| C | LYS815 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine => ECO:0000269|PubMed:28650797 |
| Chain | Residue | Details |
| C | HIS797 | |
| A | HIS797 | |
| B | HIS797 | |
| D | HIS797 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:28650797, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| C | ARG824 | |
| A | ARG824 | |
| B | ARG824 | |
| D | ARG824 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:16964243 |
| Chain | Residue | Details |
| C | PHE845 | |
| A | PHE845 | |
| B | PHE845 | |
| D | PHE845 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:28650797 |
| Chain | Residue | Details |
| C | GLU847 | |
| D | GLU847 | |
| D | LEU861 | |
| D | GLU868 | |
| C | LEU861 | |
| C | GLU868 | |
| A | GLU847 | |
| A | LEU861 | |
| A | GLU868 | |
| B | GLU847 | |
| B | LEU861 | |
| B | GLU868 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:28650797, ECO:0007744|PubMed:18669648 |
| Chain | Residue | Details |
| C | ASN851 | |
| A | ASN851 | |
| B | ASN851 | |
| D | ASN851 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q6ZQ58 |
| Chain | Residue | Details |
| C | LYS853 | |
| A | LYS853 | |
| B | LYS853 | |
| D | LYS853 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q6ZQ58, ECO:0000269|PubMed:28650797 |
| Chain | Residue | Details |
| C | ASP865 | |
| A | ASP865 | |
| B | ASP865 | |
| D | ASP865 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| C | ASP892 | |
| A | ASP892 | |
| B | ASP892 | |
| D | ASP892 |
