4M8B
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![BU of 4m8b by Molmil](/molmil-images/mine/4m8b) | Fungal Protein | Descriptor: | 1,2-ETHANEDIOL, Chain A of dsDNA containing the cis-regulatory element, Chain B of dsDNA containing the cis-regulatory element, ... | Authors: | Rosenberg, O.S, Lohse, M.L, Stroud, R.M, Johnson, A.D. | Deposit date: | 2013-08-13 | Release date: | 2014-06-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Structure of a new DNA-binding domain which regulates pathogenesis in a wide variety of fungi. Proc.Natl.Acad.Sci.USA, 111, 2014
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4M55
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![BU of 4m55 by Molmil](/molmil-images/mine/4m55) | Crystal structure of Human UDP-xylose synthase R236H substitution | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYROPHOSPHATE 2-, SULFATE ION, ... | Authors: | Walsh Jr, R.M, Polizzi, S.J, Wood, Z.A. | Deposit date: | 2013-08-08 | Release date: | 2013-08-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Man o' war mutation in UDP-alpha-D-xylose synthase favors the abortive catalytic cycle and uncovers a latent potential for hexamer formation. Biochemistry, 54, 2015
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2MFN
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![BU of 2mfn by Molmil](/molmil-images/mine/2mfn) | SOLUTION NMR STRUCTURE OF LINKED CELL ATTACHMENT MODULES OF MOUSE FIBRONECTIN CONTAINING THE RGD AND SYNERGY REGIONS, 10 STRUCTURES | Descriptor: | FIBRONECTIN | Authors: | Copie, V, Tomita, Y, Akiyama, S.K, Aota, S, Yamada, K.M, Venable, R.M, Pastor, R.W, Krueger, S, Torchia, D.A. | Deposit date: | 1998-02-11 | Release date: | 1998-04-29 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure and dynamics of linked cell attachment modules of mouse fibronectin containing the RGD and synergy regions: comparison with the human fibronectin crystal structure. J.Mol.Biol., 277, 1998
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4LAB
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![BU of 4lab by Molmil](/molmil-images/mine/4lab) | Crystal structure of the catalytic domain of RluB | Descriptor: | CHLORIDE ION, PLATINUM (II) ION, Ribosomal large subunit pseudouridine synthase B | Authors: | Czudnochowski, N, Finer-Moore, J.S, Stroud, R.M. | Deposit date: | 2013-06-19 | Release date: | 2013-11-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5043 Å) | Cite: | The mechanism of pseudouridine synthases from a covalent complex with RNA, and alternate specificity for U2605 versus U2604 between close homologs. Nucleic Acids Res., 42, 2014
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4AW1
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![BU of 4aw1 by Molmil](/molmil-images/mine/4aw1) | Human PDK1 Kinase Domain in Complex with Allosteric Compound PS210 Bound to the PIF-Pocket | Descriptor: | 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | Authors: | Schulze, J.O, Busschots, K, Lopez-Garcia, L.A, Lammi, C, Stroba, A, Zeuzem, S, Piiper, A, Alzari, P.M, Neimanis, S, Arencibia, J.M, Engel, M, Biondi, R.M. | Deposit date: | 2012-05-30 | Release date: | 2012-10-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Substrate-Selective Inhibition of Protein Kinase Pdk1 by Small Compounds that Bind to the Pif-Pocket Allosteric Docking Site. Chem.Biol., 19, 2012
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4AYI
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![BU of 4ayi by Molmil](/molmil-images/mine/4ayi) | Structure of a complex between CCPs 6 and 7 of Human Complement Factor H and Neisseria meningitidis FHbp Variant 3 Wild type | Descriptor: | 1,2-ETHANEDIOL, COMPLEMENT FACTOR H, LIPOPROTEIN GNA1870 CCOMPND 7 | Authors: | Johnson, S, Tan, L, van der Veen, S, Caesar, J, Goicoechea De Jorge, E, Everett, R.J, Bai, X, Exley, R.M, Ward, P.N, Ruivo, N, Trivedi, K, Cumber, E, Jones, R, Newham, L, Staunton, D, Borrow, R, Pickering, M, Lea, S.M, Tang, C.M. | Deposit date: | 2012-06-21 | Release date: | 2012-11-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Design and Evaluation of Meningococcal Vaccines Through Structure-Based Modification of Host and Pathogen Molecules. Plos Pathog., 8, 2012
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4M8T
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1PEF
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![BU of 1pef by Molmil](/molmil-images/mine/1pef) | |
4CY4
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![BU of 4cy4 by Molmil](/molmil-images/mine/4cy4) | The Cryo-Electron Microscopy Structure of the CorA channel from Methanocaldococcus jannaschii at 21.6 Angstrom in low magnesium. | Descriptor: | MAGNESIUM TRANSPORT PROTEIN CORA | Authors: | Cleverley, R.M, Kean, J, Shintre, C.A, Baldock, C, Derrick, J.P, Ford, R.C, Prince, S.M. | Deposit date: | 2014-04-10 | Release date: | 2015-04-22 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (21.6 Å) | Cite: | The Cryo-EM structure of the CorA channel from Methanocaldococcus jannaschii in low magnesium conditions. Biochim. Biophys. Acta, 1848, 2015
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1X7S
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![BU of 1x7s by Molmil](/molmil-images/mine/1x7s) | The X-ray crystallographic structure of the amyloidogenic variant TTR Tyr78Phe | Descriptor: | Transthyretin | Authors: | Neto-Silva, R.M, Macedo-Ribeiro, S, Pereira, P.J.B, Saraiva, M.J, Damas, A.M. | Deposit date: | 2004-08-16 | Release date: | 2005-03-22 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | X-ray crystallographic studies of two transthyretin variants: further insights into amyloidogenesis. Acta Crystallogr.,Sect.D, 61, 2005
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1XA9
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![BU of 1xa9 by Molmil](/molmil-images/mine/1xa9) | Crystal structure of yellow fluorescent protein zFP538 K66M green mutant | Descriptor: | BETA-MERCAPTOETHANOL, fluorescent protein FP538 | Authors: | Remington, S.J, Wachter, R.M, Yarbrough, D.K, Branchaud, B, Anderson, D.C, Kallio, K, Lukyanov, K.A. | Deposit date: | 2004-08-25 | Release date: | 2005-02-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | zFP538, a yellow-fluorescent protein from Zoanthus, contains a novel three-ring chromophore. Biochemistry, 44, 2005
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4LWS
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![BU of 4lws by Molmil](/molmil-images/mine/4lws) | EsxA : EsxB (SeMet) hetero-dimer from Thermomonospora curvata | Descriptor: | ACETATE ION, GLYCEROL, Uncharacterized protein | Authors: | Dovala, D.L, Cox, J.S, Stroud, R.M, Rosenberg, O.S. | Deposit date: | 2013-07-28 | Release date: | 2015-02-04 | Last modified: | 2016-09-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion. Cell(Cambridge,Mass.), 161, 2015
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4D9T
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![BU of 4d9t by Molmil](/molmil-images/mine/4d9t) | Rsk2 C-terminal Kinase Domain with inhibitor (E)-methyl 3-(4-amino-7-(3-hydroxypropyl)-5-p-tolyl-7H-pyrrolo[2,3-d]pyrimidin-6-yl)-2-cyanoacrylate | Descriptor: | Ribosomal protein S6 kinase alpha-3, SODIUM ION, methyl (2S)-3-{4-amino-7-[(1E)-3-hydroxyprop-1-en-1-yl]-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl}-2-cyanopropanoate | Authors: | Serafimova, I.M, Pufall, M.A, Krishnan, S, Duda, K, Cohen, M.S, Maglathlin, R.L, McFarland, J.M, Miller, R.M, Frodin, M, Taunton, J. | Deposit date: | 2012-01-12 | Release date: | 2012-04-25 | Last modified: | 2012-05-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles. Nat.Chem.Biol., 8, 2012
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1X7T
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![BU of 1x7t by Molmil](/molmil-images/mine/1x7t) | Structure of TTR R104H: a non-amyloidogenic variant with protective clinical effects | Descriptor: | Transthyretin | Authors: | Neto-Silva, R.M, Macedo-Ribeiro, S, Pereira, P.J.B, Coll, M, Saraiva, M.J, Damas, A.M. | Deposit date: | 2004-08-16 | Release date: | 2005-03-22 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | X-ray crystallographic studies of two transthyretin variants: further insights into amyloidogenesis. Acta Crystallogr.,Sect.D, 61, 2005
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1X93
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![BU of 1x93 by Molmil](/molmil-images/mine/1x93) | NMR Structure of Helicobacter pylori HP0222 | Descriptor: | hypothetical protein HP0222 | Authors: | Popescu, A, Karpay, A, Israel, D, Peek Jr, R.M, Krezel, A.M. | Deposit date: | 2004-08-19 | Release date: | 2005-03-22 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Helicobacter pylori protein HP0222 belongs to Arc/MetJ family of transcriptional regulators. Proteins, 59, 2005
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4LGT
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4DE8
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![BU of 4de8 by Molmil](/molmil-images/mine/4de8) | LytR-Cps2a-Psr family protein with bound octaprenyl monophosphate lipid | Descriptor: | (2Z,6Z,10Z,14Z,18Z,22Z,26Z)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-yl dihydrogen phosphate, Cps2A, DI(HYDROXYETHYL)ETHER | Authors: | Eberhardt, A, Hoyland, C.N, Vollmer, D.V, Bisle, S, Cleverley, R.M, Johnsborg, O, Havarstein, L.S, Lewis, R.J, Vollmer, W. | Deposit date: | 2012-01-20 | Release date: | 2012-04-04 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Attachment of Capsular Polysaccharide to the Cell Wall in Streptococcus pneumoniae. Microb Drug Resist, 18, 2012
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4M65
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![BU of 4m65 by Molmil](/molmil-images/mine/4m65) | In situ thermolysin crystallized on a MiTeGen micromesh with asparagine ligand | Descriptor: | 1,2-ETHANEDIOL, ASPARAGINE, CALCIUM ION, ... | Authors: | Yin, X, Scalia, A, Leroy, L, Cuttitta, C.M, Polizzo, G.M, Ericson, D.L, Roessler, C.G, Campos, O, Agarwal, R, Allaire, M, Orville, A.M, Jackimowicz, R, Ma, M.Y, Sweet, R.M, Soares, A.S. | Deposit date: | 2013-08-08 | Release date: | 2013-10-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Hitting the target: fragment screening with acoustic in situ
co-crystallization of proteins plus fragment libraries on
pin-mounted data-collection micromeshes Acta Crystallogr.,Sect.D, D70
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2MWK
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![BU of 2mwk by Molmil](/molmil-images/mine/2mwk) | Family 1 Carbohydrate-Binding Module from Trichoderma reesei Cel7A with O-mannose residues at Thr1, Ser3, and Ser14 | Descriptor: | Exoglucanase 1, alpha-D-mannopyranose | Authors: | Happs, R.M, Chen, L, Resch, M.G, Davis, M.F, Beckham, G.T, Tan, Z, Crowley, M.F. | Deposit date: | 2014-11-12 | Release date: | 2015-09-02 | Last modified: | 2020-07-29 | Method: | SOLUTION NMR | Cite: | O-glycosylation effects on family 1 carbohydrate-binding module solution structures. Febs J., 282, 2015
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1NM2
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![BU of 1nm2 by Molmil](/molmil-images/mine/1nm2) | Malonyl-CoA:ACP Transacylase | Descriptor: | ACETIC ACID, NICKEL (II) ION, malonyl CoA:acyl carrier protein malonyltransferase | Authors: | Keatinge-Clay, A.T, Shelat, A.A, Savage, D.F, Tsai, S, Miercke, L.J.W, O'Connell III, J.D, Khosla, C, Stroud, R.M. | Deposit date: | 2003-01-08 | Release date: | 2003-01-21 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Catalysis, Specificity, and ACP Docking Site of
Streptomyces coelicolor Malonyl-CoA:ACP Transacylase Structure, 11, 2003
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1YYQ
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![BU of 1yyq by Molmil](/molmil-images/mine/1yyq) | Y305F Trichodiene Synthase complexed with pyrophosphate | Descriptor: | MAGNESIUM ION, PYROPHOSPHATE 2-, Trichodiene synthase | Authors: | Vedula, L.S, Rynkiewicz, M.J, Pyun, H.J, Coates, R.M, Cane, D.E, Christianson, D.W. | Deposit date: | 2005-02-25 | Release date: | 2005-03-29 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular Recognition of the Substrate Diphosphate Group Governs Product Diversity in Trichodiene Synthase Mutants. Biochemistry, 44, 2005
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1ZMT
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![BU of 1zmt by Molmil](/molmil-images/mine/1zmt) | Structure of haloalcohol dehalogenase HheC of Agrobacterium radiobacter AD1 in complex with (R)-para-nitro styrene oxide, with a water molecule in the halide-binding site | Descriptor: | (R)-PARA-NITROSTYRENE OXIDE, Haloalcohol dehalogenase HheC | Authors: | de Jong, R.M, Tiesinga, J.J.W, Villa, A, Tang, L, Janssen, D.B, Dijkstra, B.W. | Deposit date: | 2005-05-10 | Release date: | 2005-10-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Basis for the Enantioselectivity of an Epoxide Ring Opening Reaction Catalyzed by Halo Alcohol Dehalogenase HheC. J.Am.Chem.Soc., 127, 2005
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2MWJ
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![BU of 2mwj by Molmil](/molmil-images/mine/2mwj) | Solution structure of Family 1 Carbohydrate-Binding Module from Trichoderma reesei Cel7A with O-mannose residues at Thr1 and Ser3 | Descriptor: | Exoglucanase 1, alpha-D-mannopyranose | Authors: | Happs, R.M, Chen, L, Resch, M.G, Davis, M.F, Beckham, G.T, Tan, Z, Crowley, M.F. | Deposit date: | 2014-11-12 | Release date: | 2015-09-02 | Last modified: | 2020-07-29 | Method: | SOLUTION NMR | Cite: | O-glycosylation effects on family 1 carbohydrate-binding module solution structures. Febs J., 282, 2015
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1YFP
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![BU of 1yfp by Molmil](/molmil-images/mine/1yfp) | STRUCTURE OF YELLOW-EMISSION VARIANT OF GFP | Descriptor: | YELLOW FLUORESCENT PROTEIN | Authors: | Wachter, R.M, Elsliger, M.-A, Kallio, K, Hanson, G.T, Remington, S.J. | Deposit date: | 1998-08-28 | Release date: | 1998-10-28 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis of spectral shifts in the yellow-emission variants of green fluorescent protein. Structure, 6, 1998
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4MPN
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![BU of 4mpn by Molmil](/molmil-images/mine/4mpn) | Crystal structure of pyruvate dehydrogenase kinase isoform 2 in complex with inhibitor PS10 | Descriptor: | 2-[(2,4-dihydroxyphenyl)sulfonyl]-2,3-dihydro-1H-isoindole-4,6-diol, L(+)-TARTARIC ACID, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, ... | Authors: | Gui, W.J, Tso, S.C, Chuang, J.L, Wu, C.Y, Qi, X, Tambar, U.K, Wynn, R.M, Chuang, D.T. | Deposit date: | 2013-09-13 | Release date: | 2014-01-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.752 Å) | Cite: | Structure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors Targeting the ATP-binding Pocket. J.Biol.Chem., 289, 2014
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