1RZ9
 
 | | Crystal Structure of AAV Rep complexed with the Rep-binding sequence | | Descriptor: | 26-MER, Rep protein | | Authors: | Hickman, A.B, Ronning, D.R, Perez, Z.N, Kotin, R.M, Dyda, F. | | Deposit date: | 2003-12-24 | | Release date: | 2004-02-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | The nuclease domain of adeno-associated virus rep coordinates replication initiation using two distinct DNA recognition interfaces.
Mol.Cell, 13, 2004
|
|
2H5F
 | | Denmotoxin: A the three-finger toxin from colubrid snake Boiga dendrophila with bird-specific activity | | Descriptor: | PHOSPHATE ION, POTASSIUM ION, SODIUM ION, ... | | Authors: | Pawlak, J, Kini, R.M, Stura, E.A. | | Deposit date: | 2006-05-26 | | Release date: | 2006-08-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Denmotoxin, a three-finger toxin from the colubrid snake Boiga dendrophila (Mangrove Catsnake) with bird-specific activity.
J.Biol.Chem., 281, 2006
|
|
4K5Y
 | | Crystal structure of human corticotropin-releasing factor receptor 1 (CRF1R) in complex with the antagonist CP-376395 | | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3,6-dimethyl-N-(pentan-3-yl)-2-(2,4,6-trimethylphenoxy)pyridin-4-amine, ... | | Authors: | Hollenstein, K, Kean, J, Bortolato, A, Cheng, R.K.Y, Dore, A.S, Jazayeri, A, Cooke, R.M, Weir, M, Marshall, F.H. | | Deposit date: | 2013-04-15 | | Release date: | 2013-07-17 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.977 Å) | | Cite: | Structure of class B GPCR corticotropin-releasing factor receptor 1.
Nature, 499, 2013
|
|
2F2B
 | | Crystal structure of integral membrane protein Aquaporin AqpM at 1.68A resolution | | Descriptor: | Aquaporin aqpM, GLYCEROL | | Authors: | Lee, J.K, Kozono, D, Remis, J, Kitagawa, Y, Agre, P, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP) | | Deposit date: | 2005-11-15 | | Release date: | 2005-12-06 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Structural basis for conductance by the archaeal aquaporin AqpM at 1.68 A.
Proc.Natl.Acad.Sci.Usa, 102, 2005
|
|
3ZIR
 | | minor-site specific NLS (B141) | | Descriptor: | B141NLS, IMPORTIN SUBUNIT ALPHA-2 | | Authors: | Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B. | | Deposit date: | 2013-01-10 | | Release date: | 2013-08-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha
Traffic, 14, 2013
|
|
2FLZ
 | |
2H8M
 | | N-Domain Of Grp94 In Complex With the 2-Iodo-NECA | | Descriptor: | (2S,3S,4R,5R)-5-(6-AMINO-2-IODO-9H-PURIN-9-YL)-N-ETHYL-3,4-DIHYDROXYTETRAHYDROFURAN-2-CARBOXAMIDE, Endoplasmin, PENTAETHYLENE GLYCOL, ... | | Authors: | Immormino, R.M, Gewirth, D.T. | | Deposit date: | 2006-06-07 | | Release date: | 2007-04-24 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | N-Domain Of Grp94 In Complex With the 2-Iodo-NECA
To be Published
|
|
5G47
 | | Structure of Gc glycoprotein from severe fever with thrombocytopenia syndrome virus in the trimeric postfusion conformation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, SFTSV GC | | Authors: | Halldorsson, S, Behrens, A.J, Harlos, K, Huiskonen, J.T, Elliott, R.M, Crispin, M, Brennan, B, Bowden, T.A. | | Deposit date: | 2016-05-05 | | Release date: | 2016-07-06 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structure of a Phleboviral Envelope Glycoprotein Reveals a Consolidated Model of Membrane Fusion.
Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
5GWB
 | |
2H55
 | |
4LYA
 | | EssC (ATPases 2 and 3) from Geobacillus thermodenitrificans (SeMet) | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Uncharacterized protein | | Authors: | Dovala, D.L, Bendebury, A, Cox, J.S, Stroud, R.M, Rosenberg, O.S. | | Deposit date: | 2013-07-30 | | Release date: | 2015-02-04 | | Last modified: | 2016-09-21 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion.
Cell(Cambridge,Mass.), 161, 2015
|
|
2HCH
 | |
7E9F
 | | Cryo-EM structure of the 2:1 Orc1 BAH domain in complex with nucleosome | | Descriptor: | DNA (147-mer), Histone H2A.2, Histone H2B.2, ... | | Authors: | Jiang, H, Yu, C, Liu, C.P, Han, X, Yu, Z, Xu, R.M. | | Deposit date: | 2021-03-04 | | Release date: | 2022-09-07 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Nucleosome binding relinquishes the association of the BAH domain of Orc1 with Sir1
To Be Published
|
|
7E9C
 | | Cryo-EM structure of the 1:1 Orc1 BAH domain in complex with nucleosome | | Descriptor: | DNA (147-mer), Histone H2A.2, Histone H2B.2, ... | | Authors: | Jiang, H, Yu, C, Liu, C.P, Han, X, Yu, Z, Xu, R.M. | | Deposit date: | 2021-03-04 | | Release date: | 2022-09-07 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Nucleosome binding relinquishes the association of the BAH domain of Orc1 with Sir1
To Be Published
|
|
3DM9
 | | Structures and Conformations in Solution of the Signal Recognition Particle Receptor from the archaeon Pyrococcus furiosus | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, PHOSPHATE ION, Signal recognition particle receptor | | Authors: | Egea, P.F, Tsuruta, H, Napetschnig, J, Walter, P, Stroud, R.M. | | Deposit date: | 2008-06-30 | | Release date: | 2008-11-11 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structures of the Signal Recognition Particle Receptor from the Archaeon Pyrococcus furiosus: Implications for the Targeting Step at the Membrane.
Plos One, 3, 2008
|
|
2EVU
 | | Crystal structure of aquaporin AqpM at 2.3A resolution | | Descriptor: | Aquaporin aqpM, GLYCEROL, octyl beta-D-glucopyranoside | | Authors: | Lee, J.K, Kozono, D, Remis, J, Kitagawa, Y, Agre, P, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP) | | Deposit date: | 2005-10-31 | | Release date: | 2005-12-06 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis for conductance by the archaeal aquaporin AqpM at 1.68 A.
Proc.Natl.Acad.Sci.Usa, 102, 2005
|
|
3DL0
 | | Crystal structure of adenylate kinase variant AKlse3 | | Descriptor: | Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Bannen, R.M, Bianchetti, C.M, Bingman, C.A, McCoy, J.G. | | Deposit date: | 2008-06-26 | | Release date: | 2009-06-09 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Effectiveness and limitations of local structural entropy optimization in the thermal stabilization of mesophilic and thermophilic adenylate kinases.
Proteins, 82, 2014
|
|
4CT1
 | | Human PDK1-PKCzeta Kinase Chimera in Complex with Allosteric Compound PS315 Bound to the PIF-Pocket | | Descriptor: | (2Z)-3-(biphenyl-4-yl)-5-(4-chlorophenyl)pent-2-enoic acid, 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Schulze, J.O, Zhang, H, Lopez-Garcia, L.A, Biondi, R.M. | | Deposit date: | 2014-03-11 | | Release date: | 2014-05-28 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Molecular Mechanism of Regulation of the Atypical Protein Kinase C by N-Terminal Domains and an Allosteric Small Compound.
Chem.Biol., 21, 2014
|
|
1RML
 | | NMR STUDY OF ACID FIBROBLAST GROWTH FACTOR BOUND TO 1,3,6-NAPHTHALENE TRISULPHONATE, 26 STRUCTURES | | Descriptor: | ACIDIC FIBROBLAST GROWTH FACTOR, NAPHTHALENE TRISULFONATE | | Authors: | Lozano, R.M, Jimenez, M.A, Santoro, J, Rico, M, Gimenez-Gallego, G. | | Deposit date: | 1998-05-21 | | Release date: | 1998-11-11 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of acidic fibroblast growth factor bound to 1,3, 6-naphthalenetrisulfonate: a minimal model for the anti-tumoral action of suramins and suradistas.
J.Mol.Biol., 281, 1998
|
|
4LXJ
 | | Saccharomyces cerevisiae lanosterol 14-alpha demethylase with lanosterol bound | | Descriptor: | LANOSTEROL, Lanosterol 14-alpha demethylase, OXYGEN MOLECULE, ... | | Authors: | Monk, B.C, Tomasiak, T.M, Keniya, M.V, Huschmann, F.U, Tyndall, J.D.A, O'Connell III, J.D, Cannon, R.D, McDonald, J, Rodriguez, A, Finer-Moore, J, Stroud, R.M. | | Deposit date: | 2013-07-29 | | Release date: | 2014-01-29 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer.
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4MAO
 | | RSK2 T493M C-Terminal Kinase Domain in Complex with RMM58 | | Descriptor: | (2Z)-2-(1H-1,2,4-triazol-1-yl)-3-[3-(3,4,5-trimethoxyphenyl)-1H-indazol-5-yl]prop-2-enenitrile, Ribosomal protein S6 kinase alpha-3, SODIUM ION | | Authors: | Miller, R.M, Taunton, J. | | Deposit date: | 2013-08-16 | | Release date: | 2014-10-22 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Design of reversible, cysteine-targeted Michael acceptors guided by kinetic and computational analysis.
J.Am.Chem.Soc., 136, 2014
|
|
4CT2
 | | Human PDK1-PKCzeta Kinase Chimera | | Descriptor: | 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1, ADENOSINE-5'-TRIPHOSPHATE, DITHIANE DIOL, ... | | Authors: | Schulze, J.O, Zhang, H, Lopez-Garcia, L.A, Biondi, R.M. | | Deposit date: | 2014-03-11 | | Release date: | 2014-05-28 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | Molecular Mechanism of Regulation of the Atypical Protein Kinase C by N-Terminal Domains and an Allosteric Small Compound.
Chem.Biol., 21, 2014
|
|
4M55
 | | Crystal structure of Human UDP-xylose synthase R236H substitution | | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYROPHOSPHATE 2-, SULFATE ION, ... | | Authors: | Walsh Jr, R.M, Polizzi, S.J, Wood, Z.A. | | Deposit date: | 2013-08-08 | | Release date: | 2013-08-28 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.86 Å) | | Cite: | Man o' war mutation in UDP-alpha-D-xylose synthase favors the abortive catalytic cycle and uncovers a latent potential for hexamer formation.
Biochemistry, 54, 2015
|
|
4JG6
 | | RSK2 CTD bound to 2-cyano-3-(1H-indazol-5-yl)acrylamide | | Descriptor: | (2S)-2-cyano-3-(1H-indazol-5-yl)propanamide, Ribosomal protein S6 kinase alpha-3, SODIUM ION | | Authors: | Miller, R.M, Paavilainen, V.O, Krishnan, S, Serafimova, I.M, Taunton, J. | | Deposit date: | 2013-02-28 | | Release date: | 2013-04-10 | | Last modified: | 2013-04-24 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Electrophilic fragment-based design of reversible covalent kinase inhibitors.
J.Am.Chem.Soc., 135, 2013
|
|
3DZE
 | | Crystal structure of bovine coupling Factor B bound with cadmium | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ATP synthase subunit s, mitochondrial, ... | | Authors: | Lee, J.K, Stroud, R.M, Belogrudov, G.I. | | Deposit date: | 2008-07-29 | | Release date: | 2008-08-19 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | Crystal structure of bovine mitochondrial factor B at 0.96-A resolution.
Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|
